Aktivitas Formulasi Sediaan Gel Ekstrak Etanol Daun Salam (Syzgium polyanthum) Terhadap Bakteri Propionibacterium acne dan Staphylococcus aureus Tahun 2021

Daun salam (syzgium polyanthum) mengandung flavonoid, saponin dan tanin yang berperan sebagai senyawa antibakteri. Tujuan dari penelitian ini adalah untuk mengetahui aktivitas estrak daun salam terhadap bakteri penyebab jerawat. Metode penelitian yang dilakukan meliputi, penapisan fitokimia, pembuatan estrak daun salam, formulasi sediaan gel, evaluasi sediaan gel, dan pengujian aktivitas bakteri sediaan gel dengan metode cakram difusi. Bakteri yang digunakan adalah propionibacterium acne dan staphylococcus aureus. Sediaan sediaan gel estrak etanol daun salam terdiri dari 0,5%, 1%, dan 1,55. Evaluasi sediaan gel dengan konsentrasi 0,5%, 1%,, 1,5% stabil secara fisik pada uji organoleptik, uji homogenitas, uji ph, uji daya sebar, uji adhesi, dan uji iritan. Berdasarkan hasil pengujian sediaan gel estrak daun salam yang efektif menghambat pertumbuhan bakteri dengan zona hambar menunjukkan bahwa sediaan gel estrak daun salam pada bakteri propionibacterium acne dengan konsentrasi 0,5% memiliki diameter rata-rata hambar. zona 8,22 mm, pada konsentrasi 1% memiliki zona ikatan 13,36 mm, pada konsentrasi 1,5% memiliki zona hambar 16,32 mm, perbandingan aknol 22,23. Dan pada bakteri staphylococcus aureus dengan konsentrasi 0,5% memiliki diameter rata-rata zona hambar 11,30 mm. Pada konsentrasi 1% memiliki zona hambar 13,27 mm, pada konsentrasi 1,5% memiliki zona hambar 15,27 mm, dan sebagai perbandingan aknol memiliki diameter rata-rata zona hambat sebesar 21,27 mm luas zona hambat untuk bakteri staphylococcus aureu

PENETAPAN KADAR STEROID PADA EKSTRAK DAUN TITANUS (Leea aequata L.) SECARA SPEKTROFOTOMETRI UV-VIS

The titanus plant (Leea aequata L.) is a plant that used as traditional medicine. The stems and roots are used as astringent, anthelmintic, indigestion, jaundice, chronic fever and malaria. The leaves and twigs are used as an antiseptic and to treat wounds. Steroids are secondary metabolites that have a compound structure that quite diverse. Steroids have a pharmacological effect on lowering cholesterol and anticarcinogenic. The objective of the research to determine the steroid levels in titanus leaf extract (Leea aequata L.). The analytical method used is qualitative with reagents Lieberman-Bouchard and quantitative uv-vis spectrophotometry with wavelength of 423 nm. The results of the qualitative analysis of the positive samples contained steroid compounds. The Results quantitative content of ethanol extract of titanus leaf 30.8889 mg/g, and quantitative results ethyl acetate extract content of titanus leaves 72.2649 mg/g. Validity test results obtained linearity test r=0.9994, RSD of ethanol extract 0,2852% and ethyl acetate extract 8,1120%, recovery of 101% ethanol extract and 103.667% ethyl acetate extract, LOD 2.2078 and LOQ 7,3593. SPSS analysis results p=0.000 (p<0.05). Based on the results of the research that has been done, it can be concluded that uv-vis spectrophotometry can be used to determine total steroid content of titanus leaf extract (Leea aequata L.)

ANALISIS TINGKAT KEPUASAN PASIEN ANALISIS TINGKAT KEPUASAN PASIEN RAWAT JALAN PESERTA BPJS KESEHATAN TERHADAP PELAYANAN FARMASI DI INSTALASI RSU SEMBIRING

Quality health services are health services that can satisfy every user of health services in accordance with the level of satisfaction. Satisfaction will occur if the expectations of the patient can be met by the services provided by the hospital so that it needs to be considered continuously the satisfaction and expectations of the patient. The purpose of this study was to determine the level of satisfaction of outpatients of BPJS Kesehatan participants with pharmaceutical services at the outpatient Pharmacy Installation at RSU Sembiring. The design of this study used descriptive survey research. The population in this study was 1400 patients, and the sample was 93 patients using the Slovin formula. Data collected through primary and secondary data and using univariant and bivariant analysis with the help of the SPSS computer program. The results of the chi square test obtained variables related to the satisfaction of outpatients at the general hospital, namely: Physical evidence (p value = 0.002), Reliability (p value = 0.000, Responsiveness (p value = 0.002), Guarantee (p value = 0.004), and Empathy (p value = 0.000). It is recommended to the Outpatient Pharmacy of Sembiring General Hospital to maintain a good quality of service and continue to improve the quality of service to patients