Novel phantom for evaluation of optical computer tomography scanners used for evaluation of radiotherapy gel dosimeters

There is a need for stable gel materials for phantoms used to validate optical CT scanners for the evaluation of radiotherapy gel dosimeters. Phantoms have previously been proposed based on addition of food coloring dyes to gelatine to simulate polymer gels. However, because optical extinction in these dyes operates via light absorption, they would be more suitable for simulating radiation sensitive radiochromic dosimetry gels in which the exposed region of the gel becomes more optically absorbing. To correctly simulate polymer type gels which operate via light scattering, it would be more realistic to add light scattering centers such as colloidal suspensions (sols) to the gels used in such phantoms. In this paper we present some of the results of the evaluation of a Vista optical CT scanner (Modus Medical Devices Inc.) using novel gel phantoms in which radiation exposed polymer gels are simulated by the addition of largely colorless sols of varying turbidity.3 page(s

Initial investigation of a novel light-scattering gel phantom for evaluation of optical CT scanners for radiotherapy gel dosimetry

There is a need for stable gel materials for phantoms used to validate optical computerized tomography (CT) scanners used in conjunction with radiation-induced polymerizing gel dosimeters. Phantoms based on addition of light-absorbing dyes to gelatine to simulate gel dosimeters have been employed. However, to more accurately simulate polymerizing gels one requires phantoms that employ light-scattering colloidal suspensions added to the gel. In this paper, we present the initial results of using an optical CT scanner to evaluate a novel phantom in which radiation-exposed polymer gels are simulated by the addition of colloidal suspensions of varying turbidity. The phantom may be useful as a calibration transfer standard for polymer gel dosimeters. The tests reveal some phenomena peculiar to light-scattering gels that need to be taken into account when calibrating polymer gel dosimeters.11 page(s

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

non present