Variation on a Traditional Theme: The Question of Racial and Ethnic Diversity in MLA

Following the findings from the MLA Survey of Personnel Characteristics, 2009 that pointed to discrepancies between the racial and ethnic diversity of MLA members and the general population, an analysis of the diversity of MLA’s patron base and an assessment of other organizations\u27 efforts at diversity are analyzed. Recommendations for efforts by MLA to address these discrepancies as well as justification for making such efforts follow

Survey of Music-Library Personnel Characteristics, 2009

Results from the 2009 Music Library Association (MLA) Survey of Personnel Characteristics are presented and analyzed. Areas covered include education and training, status and salaries, professional activities, and demographics of MLA members. In each area, comparisons are made to results from the study of the same name conducted in 1997

Moving From Talk to Action: What Does Successful Institutional Change Related to Equity, Diversity and Inclusion (EDI) Look Like?

Slides of a talk: Puente, M.A., Deards, K.D. (2019). Moving From Talk to Action: What Does Successful Institutional Change Related to Equity, Diversity, and Inclusion (EDI) Look Like? IDEAL’19: Advancing Inclusion, Diversity, Equity, and Accessibility in Libraries & Archives. Includes: Where is the Change? Strategies & Tools ARL’s Future Plans Resources Action & Assessmen

Theme and Variation: The Survey of MLA Personnel Characteristics

Presentation at annual national meeting of the Music Library Association, San Diego, CA, March 201

An adaptive 5G multiservice and multitenant radio access network architecture

This article provides an overview on objectives and first results of the Horizon 2020 project 5G NOvel Radio Multiservice adaptive network Architecture (5GNORMA). With 5G NORMA, leading players in the mobile ecosystem aim to underpin Europe's leadership position in 5G. The key objective of 5G NORMA is to develop a conceptually novel, adaptive and future-proof 5G mobile network architecture. This architecture will allow for adapting the network to a wide range of service specific requirements, resulting in novel service-aware and context-aware end-to-end function chaining. The technical approach is based on an innovative concept of adaptive (de)composition and allocation of mobile network functions based on end-user requirements and infrastructure capabilities. At the same time, cost savings and faster time to market are to be expected by joint deployment of logically separated multiservice and multitenant networks on common hardware and other physical resources making use of traffic multiplexing gains. In this context architectural enablers such as network function virtualization and software-defined mobile networking will play a key role for introducing the needed flexible resource assignment to logical networks and specific virtual network functions.This work has been performed in the framework of the H2020-ICT-2014-2 project 5G NORMA

Mobile network architecture evolution toward 5G

As a chain is as strong as its weakest element, so are the efficiency, flexibility, and robustness of a mobile network, which relies on a range of different functional elements and mechanisms. Indeed, the mobile network architecture needs particular attention when discussing the evolution of 3GPP EPS because it is the architecture that integrates the many different future technologies into one mobile network. This article discusses 3GPP EPS mobile network evolution as a whole, analyzing specific architecture properties that are critical in future 3GPP EPS releases. In particular, this article discusses the evolution toward a "network of functions," network slicing, and software-defined mobile network control, management, and orchestration. Furthermore, the roadmap for the future evolution of 3GPP EPS and its technology components is detailed and relevant standards defining organizations are listed.This work has been performed in the framework of the H2020-ICT-2014-2 project 5G NORMA

A Non-Death Role of the Yeast Metacaspase: Yca1p Alters Cell Cycle Dynamics

Caspase proteases are a conserved protein family predominantly known for engaging and executing apoptotic cell death. Nevertheless, in higher eukaryotes, caspases also influence a variety of cell behaviors including differentiation, proliferation and growth control. S. cerevisiae expresses a primordial caspase, yca1, and exhibits apoptosis-like death under certain stresses; however, the benefit of a dedicated death program to single cell organisms is controversial. In the absence of a clear rationale to justify the evolutionary retention of a death only pathway, we hypothesize that yca1 also influences non-apoptotic events. We report that genetic ablation and/or catalytic inactivation of Yca1p leads to a longer G1/S transition accompanied by slower growth in fermentation conditions. Downregulation of Yca1p proteolytic activity also results in failure to arrest during nocodazole treatment, indicating that Yca1p participates in the G2/M mitotic checkpoint. 20s proteasome activity and ROS staining of the Δyca1 strain is indistinguishable from its isogenic control suggesting that putative regulation of the oxidative stress response by Yca1p does not instigate the cell cycle phenotype. Our results demonstrate multiple non-death roles for yca1 in the cell cycle

The ELBA Force Field for Coarse-Grain Modeling of Lipid Membranes

A new coarse-grain model for molecular dynamics simulation of lipid membranes is presented. Following a simple and conventional approach, lipid molecules are modeled by spherical sites, each representing a group of several atoms. In contrast to common coarse-grain methods, two original (interdependent) features are here adopted. First, the main electrostatics are modeled explicitly by charges and dipoles, which interact realistically through a relative dielectric constant of unity (). Second, water molecules are represented individually through a new parametrization of the simple Stockmayer potential for polar fluids; each water molecule is therefore described by a single spherical site embedded with a point dipole. The force field is shown to accurately reproduce the main physical properties of single-species phospholipid bilayers comprising dioleoylphosphatidylcholine (DOPC) and dioleoylphosphatidylethanolamine (DOPE) in the liquid crystal phase, as well as distearoylphosphatidylcholine (DSPC) in the liquid crystal and gel phases. Insights are presented into fundamental properties and phenomena that can be difficult or impossible to study with alternative computational or experimental methods. For example, we investigate the internal pressure distribution, dipole potential, lipid diffusion, and spontaneous self-assembly. Simulations lasting up to 1.5 microseconds were conducted for systems of different sizes (128, 512 and 1058 lipids); this also allowed us to identify size-dependent artifacts that are expected to affect membrane simulations in general. Future extensions and applications are discussed, particularly in relation to the methodology's inherent multiscale capabilities