Comparison of analyses of the QTLMAS XIV common dataset. II: QTL analysis

Background - A quantitative and a binary trait for the 14th QTLMAS 2010 workshop were simulated under a model which combined additive inheritance, epistasis and imprinting. This paper aimed to compare results submitted by the participants of the workshop.Methods - The results were compared according to three criteria: the success rate (ratio of mapped QTL to the total number of simulated QTL), and the error rate (ratio of false positives to the number of reported positions), and mean distance between a true mapped QTL and the nearest submitted position. Results - Seven groups submitted results for the quantitative trait and five for the binary trait. Among the 37 simulated QTL 17 remained undetected. Success rate ranged from 0.05 to 0.43, error rate was between 0.00 and 0.92, and the mean distance ranged from 0.26 to 0.77 Mb. Conclusions - Our comparison shows that differences among methods used by the participants increases with the complexity of genetic architecture. It was particularly visible for the quantitative trait which was determined partly by non-additive QTL. Furthermore, an imprinted QTL with a large effect may remain undetected if the applied model tests only for Mendelian genes

The impact of burnout on job satisfaction the case study of the police

W pracy omówiono zagadnienia dotyczące wypalenia zawodowego oraz satysfakcji z pracy. Jej celem było zbadanie wpływu wypalenia zawodowego na satysfakcję z pracy oraz wskazanie czynników, które zwiększą satysfakcję a zmniejszą wypalenie zawodowe. Badanie zostało przeprowadzone w postaci kwestionariusza ankiety. Wyniki badań dostarczyły informacji na temat tego, że policjanci zauważają związek między satysfakcją z pracy a wypaleniem zawodowym. Podali oni szereg usprawnień jakie można wprowadzić, żeby zwiększyć pierwszy ze wspomnianych czynników zmniejszając przy tym drugi. Zaliczyli do nich: dodatkowe nagrody za sumienne wykonywanie obowiązków, możliwość podnoszenia kwalifikacji zawodowych, częstszą możliwość odpoczynku, opiekę psychologiczną, działania edukacyjne, doinwestowanie w sprzęt techniczny, lepszy odbiór społeczny zawodu policjanta. Na podstawie badań można wnioskować, że system zarządzania jednostką powinien ulec zmianie by pracownicy czuli większą satysfakcję z pracy.This paper discusses burnout and job satisfaction. Its purpose was to investigate the impact of professional burnout on job satisfaction and to point out the factors that will increase satisfaction and reduce burnout. The research was conducted as a survey. The results of the questionnaire provided information on how police officers notice the link between job satisfaction and burnout. They provided a number of improvements that can be made to increase the first factor while reducing the second. They included: additional awards for conscientious fulfilling the duties, possibility to improve professional skills, frequent resting opportunities, psychological care, educational activities, investment in technical equipment and better social acceptance of the police profession. Based on the research, we come to the conclusion that the unit management system should be changed so that employees feel more satisfied with their work

Tax havens in the context of optimizing the tax burden of the company X

W niniejszej pracy dokonano analizy literatury z zakresu podatków oraz rajów podatkowych. W pierwszej kolejności skupiono się na zagadnieniu podatków, ich genezie oraz funkcjach. Następnie przedstawiono ich podział oraz dokonano opisu najważniejszych danin z punktu widzenia dalszej symulacji. W kolejnej części omówiono funkcjonowanie rajów podatkowych z uwzględnieniem ich genezy, klasyfikacji, przyczyn oraz metod jakimi można się posłużyć wykorzystując tego typu miejsca. Następnie dokonano analizy trzech wybranych oaz podatkowych pod kontem tego jaki system fiskalny oraz warunki rejestracji są najlepsze dla przedsiębiorstwa chcącego skorzystać z usług takich obszarów. Skupiono się przede wszystkim na wysokości obciążenia podatkowego jakie musiałaby ponieść dana firma oraz na tym jaki ma to wpływ na jej wynik finansowy. Na samym końcu wyciągnięto stosowne wnioski płynące z analizy oraz podsumowano całą pracę.This work analyzes literature in the field of taxation and tax havens. In the first part, the focus was on the issue of taxes, their genesis and functions. Then, their division was presented and a description of the most important tributes from the point of view of further simulation was made. The next part discusses the functioning of tax havens, taking into account their genesis, classification, causes and methods that can be used in this type of places. Then, an analysis was made of three selected tax havens, under which the fiscal system and registration conditions are best for an enterprise wishing to use the services of such areas. The main focus was on the level of tax burden that a given company would have to incur and on how it affects its financial result. At the end, the appropriate conclusions from the analysis were done and all was summarized

Droplet digital PCR quantification of selected microRNAs in raw mastitic cow’s milk from the west of Poland

MicroRNAs (miRNAs), a class of noncoding small RNAs, have been recognised as potential biomarkers of mammary gland conditions, including bovine mastitis diagnosis. The aim of this study was to quantify selected miRNAs in the milk of mastitic cows

Magnetostrictive Functional Materials of Tb0.27Dy0.73(Fe1-xAlx)2 Series as Prospective Constituents of Magnetoelectric Composites

Structural, magnetic, and magnetostrictive properties of two-sublattice Tb0.27Dy0.73(Fe1-xAlx)2 polycrystalline intermetallic ferrimagnets (x = 0-0.2 and 1.0) were studied using X-ray powder diffraction, magnetometry, and strain gauge magnetostriction measurements. Temperature dependences of magnetization starting from 80 K were presented, and Curie temperatures were estimated. Coercive force, residual, and saturation magnetizations were determined from the magnetic hysteresis loops at room temperature. Longitudinal, transversal, form and volume magnetostrictions were investigated against the x parameter and the intensity of the magnetic field. The piezomagnetic coefficients were determined and the maximum value at the field below 1 kOe, even enhanced than that in Terfenol-D, was observed for the material TTb0.27Dy0.73(Fe0.9Al0.1)2. It means that this compound is promising for use in magnetoelectric composites

Comparison of analyses of the QTLMAS XIV common dataset. II: QTL analysis

Background: A quantitative and a binary trait for the 14th QTLMAS 2010 workshop were simulated under a model which combined additive inheritance, epistasis and imprinting. This paper aimed to compare results submitted by the participants of the workshop. Methods: The results were compared according to three criteria: the success rate (ratio of mapped QTL to the total number of simulated QTL), and the error rate (ratio of false positives to the number of reported positions), and mean distance between a true mapped QTL and the nearest submitted position. Results: Seven groups submitted results for the quantitative trait and five for the binary trait. Among the 37 simulated QTL 17 remained undetected. Success rate ranged from 0.05 to 0.43, error rate was between 0.00 and 0.92, and the mean distance ranged from 0.26 to 0.77 Mb. Conclusions: Our comparison shows that differences among methods used by the participants increases with the complexity of genetic architecture. It was particularly visible for the quantitative trait which was determined partly by non-additive QTL. Furthermore, an imprinted QTL with a large effect may remain undetected if the applied model tests only for Mendelian genes.This proceeding is published as Mucha, S., Pszczoła, M., Strabel, T. et al. Comparison of analyses of the QTLMAS XIV common dataset. II: QTL analysis. BMC Proc 5, S2 (2011). doi: 10.1186/1753-6561-5-S3-S2.</p

Opracowanie nowego „Katalogu typowych konstrukcji nawierzchni podatnych i półsztywnych”

This publication describes research and design works which were conducted at the Gdansk University of Technology for the purpose of development of new catalogue of typical flexible and semi-rigid pavement structures. The studies included: standardization of pavement structures terminology, study of foreign pavement structures catalogues and design methods, analysis of fatigue criteria for design of flexible and semi-rigid pavements, analysis of road traffic, based on weight in motion data, design of subgrade improvement, incorporation of new pavement materials, recycled and anthropogenic materials, determination of mechanistic parameters of materials and design of pavement structures using mechanistic-empirical methods of pavement design.Referat zawiera opis prac badawczych i projektowych przeprowadzonych na Politechnice Gdańskiej w celu opracowania nowego katalogu. Prace te obejmowały normalizację terminologii, studia istniejących katalogów i metod projektowych w innych krajach, analizy kryteriów zmęczeniowych do projektowania konstrukcji nawierzchni, analizy ruchu projektowego na podstawie danych ze stacji ważenia w ruchu, metody wzmacniania podłoża gruntowego, uwzględnienie nowych materiałów, materiałów z&nbsp;recyklingu i antropogenicznych, parametry mechaniczne materiałów oraz projektowanie dolnych i górnych warstw konstrukcji nawierzchni w oparciu o metody mechanistyczno-empiryczne

New polish catalogue of typical flexible and semi-rigid pavements

The paper covers the following topics important for the development of the new Polish Catalogue of typical flexible and semi-rigid pavements: reasons for preparing the new issue of the Catalogue of typical flexible and semi-rigid pavements, items introduced in the new issue, organise the terminology related to pavements, design traffic calculations and new equivalent axle load factors, new materials and technologies included in the Catalogue, classification of subgrades based on the soil material and drainage conditions, designing of lower layers and improved subgrade, designing of the main, upper layers