327 research outputs found

    Antidumping

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    We review the growing literature on the effects of antidumping, a trade policy that has emerged as the most serious impediment to international trade. Over the past 25 years countries have increasingly turned to antidumping in order to offer protection to import-competing industries. Antidumping is a trade policy where the institutional process surrounding the investigation and determinations has significant impacts beyond the antidumping duty we observe, and where the filing decision, the legal determination, and the protective impact are all endogenous with firms' decisions in the market, leading to a wealth of potential strategic actions and distorted market outcomes. This theme underlies our discussion as we review the literature in three broad areas connected with different phases of the antidumping trade policy process: 1) pre-investigation, 2) investigation, and 3) post-investigation.

    Ecological comparison of the risks of mother-to-child transmission and clinical manifestations of congenital toxoplasmosis according to prenatal treatment protocol

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    We compared the relative risks of mother-to-child transmission of Toxoplasma gondii and clinical manifestations due to congenital toxoplasmosis associated with intensive prenatal treatment in Lyon and Austria, short term treatment in 51% of Dutch women, and no treatment in Danish women. For each cohort, relative risks were standardized for gestation at seroconversion. In total, 856 mother–child pairs were studied: 549 in Lyon, 133 in Austria, 123 in Denmark and 51 in The Netherlands. The relative risk for mother-to-child transmission compared to Lyon was 1·24 (95% CI: 0·88, 1·59) in Austria; 0·59 (0·41, 0·81) in Denmark; and 0·65 (0·37, 1·01) in The Netherlands. Relative risks for clinical manifestations compared with Lyon (adjusted for follow-up to age 3 years) were: Austria 0·19 (0·04, 0·51); Denmark 0·60 (0·13, 1·08); and The Netherlands 1·46 (0·51, 2·72). There was no clear evidence that the risk of transmission or of clinical manifestations was lowest in centres with the most intensive prenatal treatment

    Economic Analysis of Increased Levels of Intramuscular Fat in Pork: Producer and Industry Opportunities

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    Ultrasound technology is available for accurately measuring intramuscular fat (IMF) in live pigs. This report provides information on the costs for pig producers and processors to implement this technology and what consumers are willing to pay for pork with improved levels of intramuscular fat. About half the participants in the willingness to pay study preferred the high IMF chop. They paid a premium of 25 percent over the low IMF chop.ultrasound technology, measure intramuscular fat live pigs, pig producer cost, pig processor costs, consumer willingness to pay, Agribusiness, Agricultural and Food Policy, Consumer/Household Economics, Demand and Price Analysis, Farm Management, Food Consumption/Nutrition/Food Safety, Livestock Production/Industries, Marketing,

    Conceptual and Scaling Evaluation of Vehicle Traffic Thermal Effects on Snow/Ice-Covered Roads*

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    The potential thermal effects of traffic on road surface thermal energy balance under frost/snow cover conditions have been largely ignored in meteorological evaluations of road ice deposit conditions. Preliminary exploration of these effects, particularly for heavy traffic scenarios with calm wind conditions and an ambient temperature of 0°C, is provided in this study using a conceptual model. Observational data were used to constrain the model, and parameterizations were employed to estimate the various heat transfer processes involved. The results indicate that, for heavy traffic situations, as well as for stopped traffic at intersections, the traffic thermal flux contribution at the surface is noticeable in a wide range of possible frost/snow-covered road conditions. The sensitivity to variation in traffic density, speed, and the emissivity of vehicle radiative surfaces, among others, is evaluated. Simple quantification of these traffic thermal effects, which might be considered in operational meteorological model forecasting of icy road conditions, is offered

    Multi-scale waves in sound-proof global simulations with EULAG

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    EULAG is a computational model for simulating flows across a wide range of scales and physical scenarios. A standard option employs an anelastic approximation to capture nonhydrostatic effects and simultaneously filter sound waves from the solution. In this study, we examine a localized gravity wave packet generated by instabilities in Held-Suarez climates. Although still simplified versus the Earth’s atmosphere, a rich set of planetary wave instabilities and ensuing radiated gravity waves can arise. Wave packets are observed that have lifetimes ≤ 2 days, are negligibly impacted by Coriolis force, and do not show the rotational effects of differential jet advection typical of inertia-gravity waves. Linear modal analysis shows that wavelength, period, and phase speed fit the dispersion equation to within a mean difference of ∼ 4%, suggesting an excellent fit. However, the group velocities match poorly even though a propagation of uncertainty analysis indicates that they should be predicted as well as the phase velocities. Theoretical arguments suggest the discrepancy is due to nonlinearity — a strong southerly flow leads to a critical surface forming to the southwest of the wave packet that prevents the expected propagation

    Tubulin response to intense nanosecond-scale electric field in molecular dynamics simulation

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    Intense pulsed electric fields are known to act at the cell membrane level and are already being exploited in biomedical and biotechnological applications. However, it is not clear if electric pulses within biomedically-attainable parameters could directly influence intra-cellular components such as cytoskeletal proteins. If so, a molecular mechanism of action could be uncovered for therapeutic applications of such electric fields. To help clarify this question, we first identified that a tubulin heterodimer is a natural biological target for intense electric fields due to its exceptional electric properties and crucial roles played in cell division. Using molecular dynamics simulations, we then demonstrated that an intense - yet experimentally attainable - electric field of nanosecond duration can affect the bβ-tubulin’s C-terminus conformations and also influence local electrostatic properties at the GTPase as well as the binding sites of major tubulin drugs site. Our results suggest that intense nanosecond electric pulses could be used for physical modulation of microtubule dynamics. Since a nanosecond pulsed electric field can penetrate the tissues and cellular membranes due to its broadband spectrum, our results are also potentially significant for the development of new therapeutic protocols

    Degradation of Filamin in Aged Pork Loins Classified by High and Low Star Probe Values

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    Filamin is necessary to maintain the integrity of muscle structure. Postmortem degradation of filamin results in loss of organizational structure at the Z-disk and improves meat tenderness. Intact and degraded filamin was successfully identified in aged pork loin. The removal of amino acids to form this degradation product is likely the first cleavage of intact filamin observed in postmortem muscle. A significant decrease in abundance of intact filamin in low star probe (SP) value samples demonstrates that degradation of filamin varies when aging period and pH are similar. Filamin degradation was significantly different in SP groups, suggesting that filamin proteolysis and formation of degradation products may have an impact on the SP values of aged pork loin
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