13 research outputs found

    New precision measurement of the J/ψJ/\psi- and ψ\psi' -meson masses

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    A new high precision measurement of the J/ψJ/\psi- and ψ\psi'-meson masses has been performed at the VEPP-4M collider using the KEDR detector. The resonant depolarization method has been employed for the absolute calibration of the beam energy. The following mass values have been obtained: MJ/ψ=3096.917±0.010±0.007M_{J/\psi} = 3096.917 \pm 0.010 \pm 0.007 MeV, Mψ=3686.111±0.025±0.009M_{\psi'} = 3686.111 \pm 0.025 \pm 0.009 MeV. The relative measurement accuracy has reached 4.1064. 10^{-6} for J/ψJ/\psi and 7.1067. 10^{-6} for ψ\psi', approximately 3 times better than in the previous precise experiments.Comment: 12 pages, 4 tables, 10 figure

    The technique and the algorithm of the determination of the main design parameters of the low mass centrifugal pump

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    Abstract: The technique and the algorithm of determination of the main design parameters of the low mass flow rate centrifugal pump with semi-open impellers were presented in this paper. The leakage of the working fluid in the axial clearance of the pump and the hydraulic losses at the inlet to the impeller were taken into account in the above-mentioned method. The proposed method can be used for the design of the low mass centrifugal pumps.Note: Research direction:Theoretical and applied problems of mechanic

    The dynamics of the rotor of the low mass centrifugal pumps with the hydrostatic bearings and the driven by the DC motors

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    Abstract: The mathematical model of the rotor dynamics of the low mass centrifugal pump with the hydrostatic bearings when starting it up were presented in this paper. The time-dependent of the angular velocity of the rotor and the height of his ascent were determined as a result of the mathematical simulation. The proposed mathematical model can be used in the design of the low mass centrifugal pumps with the hydrostatic bearings used in various industries.Note: Research direction:Mathematical modelling in actual problems of science and technic

    NotI linking/jumping clones of human chromosome 3: mapping of the TFRC, RAB7 and HAUSP genes to regions rearranged in leukemia and deleted in solid tumors

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    AbstractBy applying the `recognition mask' strategy to 300 mammalian sequences containing NotI sites we demonstrated that 5′ ends of genes are highly enriched in NotI sites. A NotI linking clone NL2-252 (D3S1678) containing transferrin receptor (TFRC) gene was used as an initial point for chromosomal jumping. One of the jumping clones, J21-045 traverses 210 kbp and links NL2-252 to NL26 (D3S1632), a NotI linking clone containing highly polymorphic sequences. The TFRC gene was mapped to 3q29, close to the telomeric marker D3S2344, by linkage analysis, a panel of hybrid cell lines, GeneBridge 4 panel and FISH. Clone NLM-007 (D3S4302) was found to contain ras-homologous gene RAB7. By FISH and a panel of hybrid cell lines this gene was mapped to 3q21. This region is of particular interest due to frequent rearrangements in different types of leukemia. Clone L2-081 (D3S4283) containing new member of ubiquitin-specific proteases (HAUSP gene) was localized in 3p21 inspiring further investigation of involvement of this gene in development of lung and renal carcinomas

    Analysis of NotI linking clones isolated from human chromosome 3 specific libraries

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    We have partially sequenced more than 1000 NotI linking clones isolated from human chromosome 3-specific libraries. Of these clones, 152 were unique chromosome 3-specific clones. The clones were precisely mapped using a combination of fluorescence in situ hybridization (FISH) and hybridization to somatic cell or radiation hybrids. Two- and three-color FISH was used to order the clones that mapped to the same chromosomal region, and in some cases, chromosome jumping was used to resolve ambiguous mapping. When this NotI restriction map was compared with the yeast artificial chromosome (YAC) based chromosome 3 map, significant differences in several chromosome 3 regions were observed. A search of the EMBL nucleotide database with these sequences revealed homologies (90–100%) to more than 100 different genes or expressed sequence tags (ESTs). Many of these homologies were used to map new genes to chromosome 3. These results suggest that sequencing NotI linking clones, and sequencing CpG islands in general, may complement the EST project and aid in the discovery of all human genes by sequencing random cDNAs. This method may also yield information that cannot be obtained by the EST project alone; namely, the identification of the 5′ ends of genes, including potential promoter/enhancer regions and other regulatory sequence
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