19 research outputs found
Outpatient technologies in policlinic department of regional oncology center
ΠΠΏ experience of our day hospital at the polyclinic GBUZ CHOKOD that allows to solve the problem to improve the organization of specialized medical care, an increase in work intensity outpatient care clinic, increasing the availability and quality of specialized medical care.ΠΡΠΈΠ²Π΅Π΄Π΅Π½ Π½Π°Ρ ΠΎΠΏΡΡ ΠΎΡΠ³Π°Π½ΠΈΠ·Π°ΡΠΈΠΈ Π΄Π½Π΅Π²Π½ΠΎΠ³ΠΎ ΡΡΠ°ΡΠΈΠΎΠ½Π°ΡΠ° ΠΏΡΠΈ ΠΏΠΎΠ»ΠΈΠΊΠ»ΠΈΠ½ΠΈΠΊΠ΅ ΠΠΠ£Π Π§ΠΠΠΠ, ΠΏΠΎΠ·Π²ΠΎΠ»ΡΡΡΠΈΠΉ ΡΠ΅ΡΠΈΡΡ Π·Π°Π΄Π°ΡΡ ΠΏΠΎ ΡΠΎΠ²Π΅ΡΡΠ΅Π½ΡΡΠ²ΠΎΠ²Π°Π½ΠΈΡ ΠΎΡΠ³Π°Π½ΠΈΠ·Π°ΡΠΈΠΈ ΡΠΏΠ΅ΡΠΈΠ°Π»ΠΈΠ·ΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠΉ ΠΌΠ΅Π΄ΠΈΡΠΈΠ½ΡΠΊΠΎΠΉ ΠΏΠΎΠΌΠΎΡΠΈ, ΡΠ²Π΅Π»ΠΈΡΠ΅Π½ΠΈΡ ΠΈΠ½ΡΠ΅Π½ΡΠΈΠ²Π½ΠΎΡΡΠΈ ΡΠ°Π±ΠΎΡΡ Π°ΠΌΠ±ΡΠ»Π°ΡΠΎΡΠ½ΠΎ-ΠΏΠΎΠ»ΠΈΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΈΡ
Π·Π²Π΅Π½Π° Π΄ΠΈΡΠΏΠ°Π½ΡΠ΅ΡΠ°, ΠΏΠΎΠ²ΡΡΠ΅Π½ΠΈΡ Π΄ΠΎΡΡΡΠΏΠ½ΠΎΡΡΠΈ ΠΈ ΠΊΠ°ΡΠ΅ΡΡΠ²Π° ΡΠΏΠ΅ΡΠΈΠ°Π»ΠΈΠ·ΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠΉ ΠΌΠ΅Π΄ΠΈΡΠΈΠ½ΡΠΊΠΎΠΉ ΠΏΠΎΠΌΠΎΡΠΈ
Functional activity of blood eosinophils in patients with <i>Opisthorchis felineus</i> invasion
Aim. To study the functional activity of blood eosinophils in patients with Opisthorchis felineus (O. felineus) invasion.Material and methods. A total of 328 patients with O. felineus invasion (120 men and 208 women, mean age 40.3 years) and 34 practically healthy patients (14 men and 20 women, mean age 41.1 years) aged 18 to 70 years were examined. The main method for diagnosing opisthorchiasis was the determination of eggs or bodies of adult parasites in the duodenal contents and/or feces, which was used in all 328 patients with opisthorchiasis. All patients underwent a complete blood count and biochemical blood test, esophagogastroduodenoscopy and ultrasound examination of the abdominal organs. The study of the functional activity of blood eosinophils was carried out in 42 patients with opisthorchiasis and 34 healthy individuals from the control group by chemiluminescent analysis with the measurement of the intensity of production of reactive oxygen species in spontaneous and zymosan-induced reactions in lucigenin- and luminol-dependent processes.Results. The frequency of eosinophils in the complete blood count above 5% in the examined patients with opisthorchiasis was 19.5%. An increase in the content of eosinophils in the blood in patients with opisthorchiasis was associated with an increase in the frequency of complaints of pain in the right hypochondrium, pruritus, skin rashes, an increase in the proportion of leukopenia and neutropenia, an increase in the level of gamma-glutamyl transpeptidase in the blood, and an increase in the frequency of ultrasound signs of cholecystitis. At the same time, a pronounced increase in the functional activity of blood eosinophils, determined by the chemiluminescent method, was observed in patients with O. felineus invasion.Conclusions. Patients with O. felineus invasion with an increase in the content of eosinophils in the blood due to the likelihood of an aggressive course of the pathology deserve the close attention of practitioners with the need for a thorough comprehensive examination of patients, including immunological methods