Modeling transient aspects of coherence-driven electron transport

Non-equilibrium Green's function formalism (NEGF) by employing time-dependent (TD) perturbation theory is used to solve the electronic equations of motion of model systems under potential biasing conditions. The time propagation is performed in the full frequency domain of the two time variables representation. We analyze transient aspects of the resulting conductance under effects of applied direct-current and alternating current potentials. The coherence induced response dependence on different aspects of the applied perturbation is resolved in time and analyzed using calculated TD distributions of the current operator.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/85419/1/jpconf10_220_012008.pd

Academic Performance and Behavioral Patterns

Identifying the factors that influence academic performance is an essential part of educational research. Previous studies have documented the importance of personality traits, class attendance, and social network structure. Because most of these analyses were based on a single behavioral aspect and/or small sample sizes, there is currently no quantification of the interplay of these factors. Here, we study the academic performance among a cohort of 538 undergraduate students forming a single, densely connected social network. Our work is based on data collected using smartphones, which the students used as their primary phones for two years. The availability of multi-channel data from a single population allows us to directly compare the explanatory power of individual and social characteristics. We find that the most informative indicators of performance are based on social ties and that network indicators result in better model performance than individual characteristics (including both personality and class attendance). We confirm earlier findings that class attendance is the most important predictor among individual characteristics. Finally, our results suggest the presence of strong homophily and/or peer effects among university students

Bone Marrow Transplantation for Feline Mucopolysaccharidosis I

Severe mucopolysaccharidosis type I (MPS I) is a fatal neuropathic lysosomal storage disorder with significant skeletal involvement. Treatment involves bone marrow transplantation (BMT), and although effective, is suboptimal, due to treatment sequelae and residual disease. Improved approaches will need to be tested in animal models and compared to BMT. Herein we report on bone marrow transplantation to treat feline mucopolysaccharidosis I (MPS I). Five MPS I stably engrafted kittens, transplanted with unfractionated bone marrow (6.3 × 107–1.1 × 109 nucleated bone marrow cells per kilogram) were monitored for 13–37 months post-engraftment. The tissue total glycosaminoglycan (GAG) content was reduced to normal levels in liver, spleen, kidney, heart muscle, lung, and thyroid. Aorta GAG content was between normal and affected levels. Treated cats had a significant decrease in the brain GAG levels relative to untreated MPS I cats and a paradoxical decrease relative to normal cats. The α-l-iduronidase (IDUA) activity in the livers and spleens of transplanted MPS I cats approached heterozygote levels. In kidney cortex, aorta, heart muscle, and cerebrum, there were decreases in GAG without significant increases in detectable IDUA activity. Treated animals had improved mobility and decreased radiographic signs of disease. However, significant pathology remained, especially in the cervical spine. Corneal clouding appeared improved in some animals. Immunohistochemical and biochemical analysis documented decreased central nervous system ganglioside storage. This large animal MPS I study will serve as a benchmark of future therapies designed to improve on BMT

The Benefits of Believing in Chance or Fate: External Locus of Control as a Protective Factor for Coping with the Death of a Spouse

The death of a spouse is an extremely stressful life event that consequently causes a large drop in life satisfaction. Reactivity to the loss, however, varies markedly, a phenomenon that is currently not well understood. Because lack of controllability essentially contributes to the stressful nature of this incident, we analyzed whether individual differences in the belief in external control influence the coping process. To examine this issue, widowed individuals (N = 414) from a large-scaled panel study were followed for the 4 years before and after the loss by using a latent growth model. Results showed that belief in external control led to a considerably smaller decline in life satisfaction and higher scores in the year of the loss. Thus, although usually regarded as a risk factor, belief in external control acts as a protective factor for coping with the death of a spouse

The influence of exploration mode, orientation, and configuration on the haptic Mu« ller-Lyer illusion

We studied the impact of manner of exploration, orientation, spatial position, and configuration on the haptic Mu« ller-Lyer illusion. Blindfolded sighted subjects felt raised-line Mu« ller-Lyer and control stimuli. The stimuli were felt by tracing with the index finger, free exploration, grasping with the index finger and thumb, or by measuring with the use of any two or more fingers. For haptic judgments of extent a sliding tangible ruler was used. The illusion was present in all exploration conditions, with overestimation of the wings-out compared to wings-in stimuli. Tracing with the index finger reduced the magnitude of the illusion. However, tracing and grasping induced an overall underestimation of size. The illusion was greatly attenuated when stimuli were felt with the index fingers of both hands. Illusory misperception was not altered by the position in space of the Mu« ller-Lyer stimuli. No effects of changes in the thickness of the line shaft were found, but there were effects of the length of the wing endings for the smaller, 5.1 cm stimuli. The theoretical and practical implications of the results are discussed

The influence of exploration mode, orientation, and configuration on the haptic Mu« ller-Lyer illusion

We studied the impact of manner of exploration, orientation, spatial position, and configuration on the haptic Mu« ller-Lyer illusion. Blindfolded sighted subjects felt raised-line Mu« ller-Lyer and control stimuli. The stimuli were felt by tracing with the index finger, free exploration, grasping with the index finger and thumb, or by measuring with the use of any two or more fingers. For haptic judgments of extent a sliding tangible ruler was used. The illusion was present in all exploration conditions, with overestimation of the wings-out compared to wings-in stimuli. Tracing with the index finger reduced the magnitude of the illusion. However, tracing and grasping induced an overall underestimation of size. The illusion was greatly attenuated when stimuli were felt with the index fingers of both hands. Illusory misperception was not altered by the position in space of the Mu« ller-Lyer stimuli. No effects of changes in the thickness of the line shaft were found, but there were effects of the length of the wing endings for the smaller, 5.1 cm stimuli. The theoretical and practical implications of the results are discussed