2,205 research outputs found

    Ebola virus disease (EVD) outbreak re-emergence regulation in East Africa: preparedness and vaccination perspective

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    Sudan ebolavirus (SUDV), Bundibugyo ebolavirus, Taï Forest ebolavirus, and Zaire ebolavirus (EBOV) are the most potentially life-threatening and grievous species reported among the Ebolavirus genus. Previously, the most common cases pointed to EBOV as the primary causative agent of Ebolavirus epidemics and fatalities. From 2013 to 2016, a devastating EBOV outbreak in West Africa resulted in 29,000 illness cases, prompting WHO global member countries to prioritise vaccine candidates in the early stages of development. The impending spread of EBOV in Guinea, Uganda, and the Democratic Republic of the Congo highlighted the ongoing need for secure and effective vaccine programmes against emerging infections using the most secure deployment precautions and methodologies. The West Africa outbreak and all current outbreaks in other countries have been prevented through the effective immunisation of healthy individuals through vaccination and their interactions with identified patients, medical practitioners, and frontline emergency professionals. Despite the fact that EBOV outbreaks previously only infected a small percentage of the global population, they have occasionally caused widespread suffering and huge economic costs in endemic countries. Reported transmission of such viruses beyond nonendemic zones in conjunction with the bioweapon potentiality of ebolaviruses necessitates the discovery and production of EBOV vaccines globally.O

    Constraints on the χ_(c1) versus χ_(c2) polarizations in proton-proton collisions at √s = 8 TeV

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    The polarizations of promptly produced χ_(c1) and χ_(c2) mesons are studied using data collected by the CMS experiment at the LHC, in proton-proton collisions at √s=8  TeV. The χ_c states are reconstructed via their radiative decays χ_c → J/ψγ, with the photons being measured through conversions to e⁺e⁻, which allows the two states to be well resolved. The polarizations are measured in the helicity frame, through the analysis of the χ_(c2) to χ_(c1) yield ratio as a function of the polar or azimuthal angle of the positive muon emitted in the J/ψ → μ⁺μ⁻ decay, in three bins of J/ψ transverse momentum. While no differences are seen between the two states in terms of azimuthal decay angle distributions, they are observed to have significantly different polar anisotropies. The measurement favors a scenario where at least one of the two states is strongly polarized along the helicity quantization axis, in agreement with nonrelativistic quantum chromodynamics predictions. This is the first measurement of significantly polarized quarkonia produced at high transverse momentum
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