2,263 research outputs found

    Literacy in Money Management - A Path to Sustainable Growth

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    Understanding the language of money is an integral part of the sustainable development of an economy. The world of financial markets plays a major role for transforming developing economies into global powers. If we look at the future, fancier market models may be developed; those even more accurate than what they are today. However, the incremental value addition in this model creation industry comprises of a hindrance in the form of lack of awareness and education of the Indian masses. Dynamism stimulates a sense of continual excitement and with the global environment becoming more complex; market participants seek a far more sophisticated education imparting mechanism to tackle fi nancial risks and achieve sustainable growth. The Indian financial markets hold immense potential for coming generations. However, we are driven by too much leverage and too little confidence as we lack the power of knowledge. To avoid ending up with an overleveraged economy further leading to credit bubbles and economic imbalances, the need to address knowledge dissemination concerns from a complex global perspective rises further. This research is mainly to set forth the path toward building a robust fi nancial literacy promotion mechanism to build a healthier and confident economy. The study mainly focuses on the initiatives in this area by eminent organizations and their contribution toward encouraging sustainability through literacy of managing money. The study would involve primary and secondary methods of data collection to analyze current trends and recommend improvisations in the same

    Solute Release from Polymer Capsules Loaded With Liposomes

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    Polymer capsules and lipid vesicles (liposomes) are two types of containers that have been extensively studied for their applications in drug delivery. In this thesis, we explore a hybrid of these two structures (i.e. polymer capsules bearing encapsulated liposomes) and study the release of solute from these structures. The capsules are made by contacting the anionic biopolymer alginate with multivalent cations such as calcium (Ca2+) or holmium (Ho3+), which crosslink the alginate chains. Liposomes prepared from conventional phospholipids are loaded with a model solute (an aromatic dye) and then encapsulated in the alginate capsules. We study the effects of different variables on solute release, including the capsule size and architecture, crosslinking ion type and concentration, and crosslinking time. In addition, we compare release from the bare capsules (not containing liposomes) with that from capsules containing liposomes. A key finding is that the latter releases solute over a much longer time compared to the former. Overall, the results from this study will guide the design of new structures for drug delivery applications

    Chediak higashi syndrome: A case report of rare anomaly

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    Chediak Higashi syndrome (CHS) is a rare autosomal recessive immunodeficiency disorder that arises due to the mutation of a trafficking protein which leads to a decrease in phagocytosis. This results in frequent pyogenic infections, albinism, and peripheral neuropathy. Infections in these patients tend to be very serious and life-threatening. CHS is caused by mutations in a gene LYST on chromosome 1. Here, we report the case of CHS in a 4-year-old boy who presented to us with recurrent fever, splenomegaly, and hypopigmentation. This case is being presented due to its rarity and presentation of pancytopenia without hemophagocytosis

    Microvessel rupture induced by high-intensity therapeutic ultrasound—a study of parameter sensitivity in a simple in vivo model

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    Safety analyses of transcranial therapeutic ultrasound procedures require knowledge of the dependence of the rupture probability and rupture time upon sonication parameters. As previous vessel-rupture studies have concentrated on a specific set of exposure conditions, there is a need for more comprehensive parametric studies. Probability of rupture and rupture times were measured by exposing the large blood vessel of a live earthworm to high-intensity focused ultrasound pulse trains of various characteristics. Pressures generated by the ultrasound transducers were estimated through numerical solutions to the KZK (Khokhlov-Zabolotskaya-Kuznetsov) equation. Three ultrasound frequencies (1.1, 2.5, and 3.3 MHz) were considered, as were three pulse repetition frequencies (1, 3, and 10 Hz), and two duty factors (0.0001, 0.001). The pressures produced ranged from 4 to 18 MPa. Exposures of up to 10 min in duration were employed. Trials were repeated an average of 11 times. No trends as a function of pulse repetition rate were identifiable, for either probability of rupture or rupture time. Rupture time was found to be a strong function of duty factor at the lower pressures; at 1.1 MHz the rupture time was an order of magnitude lower for the 0.001 duty factor than the 0.0001. At moderate pressures, the difference between the duty factors was less, and there was essentially no difference between duty factors at the highest pressure. Probability of rupture was not found to be a strong function of duty factor. Rupture thresholds were about 4 MPa for the 1.1 MHz frequency, 7 MPa at 3.3 MHz, and 11 MPa for the 2.5 MHz, though the pressure value at 2.5 MHz frequency will likely be reduced when steep-angle corrections are accounted for in the KZK model used to estimate pressures. Mechanical index provided a better collapse of the data (less separation of the curves pertaining to the different frequencies) than peak negative pressure, for both probability of rupture and rupture time. The results provide a database with which investigations in more complex animal models can be compared, potentially establishing trends by which bioeffects in human vessels can be estimated.https://doi.org/10.1186/s40349-017-0082-

    Constraints on the χ_(c1) versus χ_(c2) polarizations in proton-proton collisions at √s = 8 TeV

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    The polarizations of promptly produced χ_(c1) and χ_(c2) mesons are studied using data collected by the CMS experiment at the LHC, in proton-proton collisions at √s=8  TeV. The χ_c states are reconstructed via their radiative decays χ_c → J/ψγ, with the photons being measured through conversions to e⁺e⁻, which allows the two states to be well resolved. The polarizations are measured in the helicity frame, through the analysis of the χ_(c2) to χ_(c1) yield ratio as a function of the polar or azimuthal angle of the positive muon emitted in the J/ψ → μ⁺μ⁻ decay, in three bins of J/ψ transverse momentum. While no differences are seen between the two states in terms of azimuthal decay angle distributions, they are observed to have significantly different polar anisotropies. The measurement favors a scenario where at least one of the two states is strongly polarized along the helicity quantization axis, in agreement with nonrelativistic quantum chromodynamics predictions. This is the first measurement of significantly polarized quarkonia produced at high transverse momentum
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