Investigating the training and development of O24U NZ Ltd to improve employees’ performance

The topic of this research is to investigate the training and development of O24U to improve employees’ performance. This research aims to: firstly, investigate the process of O24U NZ Ltd using training and development; secondly, to research the relationship between the training and development and employees’ performance; and finally, to identify several recommendations on training and development to improve employees’ performance. O24U NZ Ltd was founded in 2015. and is located at Hamilton CBD. It mainly provides healthcare products made in New Zealand and Australia. There are four people currently working for the store, and there are about 20 competitors of O24U, such as Green, Sunshine and DeKang, in Hamilton. Literature for the review was chosen through the scope (training and development, healthcare product industry in New Zealand and China, strategic human resource management (SHRM) and benchmarking). The researcher conducted four interviews to gather the necessary data for this study (3 employees of O24U and one staff member from one of the competitors). The data were analysed through inductive thematic analysis. Six themes were analysed: the purpose, type and issues of training and development, on-boarding, SHRM and the benefits of Oceanian healthcare products. The researcher found that training and development are vital for any organisation, on-the-job training has become the most popular approach to operating training and development programmes, and the main function of SHRM is to manage employees’ values creation capacities. Several recommendations are made which include five aspects (situation of the store, using systems, stocktaking, packaging and cleaning)

Rinse-resistant superhydrophobic block copolymer fabrics by electrospinning, electrospraying and thermally-induced self-assembly

An inherent problem that restricts the practical application of superhydrophobic materials is that the superhydrophobic property is not sustainable; it can be diminished, or even lost, when the surface is physically damaged. In this work, we present an efficient approach for the fabrication of superhydrophobic fibrous fabrics with great rinse-resistance where a block copolymer has been electrospun into a nanofibrous mesh while micro-sized beads have been subsequently electrosprayed to give a morphologically composite material. The intricate nano- and microstructure of the composite was then fixed by thermally annealing the block copolymer to induce self-assembly and interdigitation of the microphase separated domains. To demonstrate this approach, a polystyrene-b-poly(ethylene-co-butylene)-b-polystyrene (SEBS) nanofibrous scaffold was produced by electrospinning before SEBS beads were electrosprayed into this mesh to form a hierarchical micro/nanostructure of beads and fibers. The effects of type and density of SEBS beads on the surface morphology and wetting properties of composite membranes were studied extensively. Compared with a neat SEBS fibrous mesh, the composite membrane had enhanced hydrophobic properties. The static water contact angle increased from 139° (±3°) to 156° (±1°), while the sliding angle decreased to 8° (±1°) from nearly 90°. In order to increase the rinse-resistance of the composite membrane, a thermal annealing step was applied to physically bind the fibers and beads. Importantly, after 200 hours of water flushing, the hierarchical surface structure and superhydrophobicity of the composite membrane were well retained. This work provides a new route for the creation of superhydrophobic fabrics with potential in self-cleaning applications

Depletion of B-cells with rituximab improves endothelial function and reduces inflammation among individuals with rheumatoid arthritis.

BackgroundIndividuals with rheumatoid arthritis (RA) are at increased risk for cardiovascular disease, partly due to systemic inflammation and endothelial dysfunction. B-cells play an important pathogenic role in the inflammatory process that drives RA disease activity. Rituximab, a chimeric murine/human monoclonal antibody that depletes B-cells, is an effective therapy for RA. The purpose of this study was to determine whether B-cell depletion with rituximab reduces systemic inflammation and improves macrovascular (brachial artery flow-mediated dilation, FMD) and microvascular (reactive hyperemia) endothelial function in RA patients.Methods and resultsRA patients received a single course of rituximab (1000 mg IV infusion at baseline and on day 15). FMD, reactive hyperemia, inflammatory markers, and clinical assessments were performed at baseline, week 12, and week 24. Twenty patients (95% female, median age 54 years) completed the study. Following treatment, FMD improved from a baseline of 4.5±0.4% to 6.4±0.6% at 12 weeks (mean±SE; P<0.0001), followed by a decline at week 24; a similar pattern was observed for hyperemic velocity. Significant decreases in RA disease scores, high-sensitivity C-reactive protein, erythrocyte sedimentation rate, and circulating CD19+ B-cells were sustained through week 24. Cholesterol and triglycerides became significantly although modestly elevated during the study.ConclusionsDepletion of B-cells with rituximab improved macrovascular and microvascular endothelial function and reduced systemic inflammation, despite modest elevation in lipids. Given these results, rituximab should be evaluated in the future for its possible role in reducing excess cardiovascular risk in RA.Clinical trial registrationURL http://ClinicalTrials.gov. Unique identifier: NCT00844714

BATCH REVERSE OSMOSIS: EXPERIMENTAL RESULTS, MODEL VALIDATION, AND DESIGN IMPLICATIONS

In theory, batch reverse osmosis (RO) systems can achieve the lowest practical energy consumption by varying feed pressure over time. However, few batch RO syste ms have been built and operated. We have tested a bench-scale prototype of a true batch RO system using a bladder and a 2.5” (6.35 cm) spiral wound membrane element. Some practical issues in implementing batch RO include system start-up time, system depressurization, osmotic backwash during the reset phases, and lower permeate quality. This study is the first to validate batch models by measuring the hydraulic work of both the high pressure pump and the circulation pump. The experimental measurements agree well with the model (error ≤ 3 %) after accounting for concentration polarization. We used the validated model to calculate the energy savings of true batch systems at higher salinities and recovery ratios. We find that the energy savings achievable by true batch systems are less than previously thought, but still significant at relatively high recoveries. At 50% recovery of seawater feed, a batch RO plant could save 15% of the energy consumed by a continuous RO plant while still maintaining the same effective flux. Further studies should identify the additional costs associated with batch RO in order to identify the operating conditions where batch RO will be an economically favorable option compared to conventional continuous RO

Moderate-vigorous physical activity and health-related quality of life among Hispanic/Latino adults in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).

BackgroundPhysical activity is a modifiable healthy behavior that has been shown to positively influence health-related quality of life. However, research examining the link between physical activity and health-related quality of life among Hispanic/Latino adults is limited and inconsistent. The purpose of this study is to assess whether accelerometer-measured moderate-vigorous physical activity (MVPA) is associated with self-reported (a) mental health-related quality of life, and (b) physical health-related quality of life among diverse Hispanic/Latino adults in the US.MethodsCross-sectional data from 12,379 adults ages 18-74 years in 2008-2011, who participated in HCHS/SOL and had complete data were analyzed using complex survey design methods. Accelerometer data were categorized into no MVPA, low, moderate, and high MVPA. Health-related quality of life was assessed with the Short-Form 12 and we used the mental and physical component subscales where higher scores indicate better health-related quality of life. Multivariate linear regression models were used to derive adjusted means with 95% confidence intervals and linear trends.ResultsWe observed no significant linear trend between accelerometer-measured MVPA and mental health-related quality of life (ptrend = 0.73). There was a significant positive association between MVPA and physical health-related quality of life (ptrend < 0.001) where higher MVPA corresponded with higher scores in physical health-related quality of life. The adjusted means were 46.67 (44.85-48.48) for no MVPA, 49.33 (49.03-49.63) for low MVPA, 50.61 (50.09-51.13) for moderate MVPA, and 51.36 (50.86-51.86) for high MVPA.ConclusionsAmong diverse Hispanic/Latino adults in the US, accelerometer-measured MVPA was associated with physical health-related quality of life, but not mental health-related quality of life. Future interventions should evaluate if increases in MVPA lead to improvements in health-related quality of life

The impact of histopathology and NAB2-STAT6 fusion subtype in classification and grading of meningeal solitary fibrous tumor/hemangiopericytoma.

Meningeal solitary fibrous tumor (SFT)/hemangiopericytoma (HPC) is a rare tumor with propensity for recurrence and metastasis. Although multiple classification schemes have been proposed, optimal risk stratification remains unclear, and the prognostic impact of fusion status is uncertain. We compared the 2016 WHO CNS tumor grading scheme (CNS-G), a three-tier system based on histopathologic phenotype and mitotic count, to the 2013 WHO soft-tissue counterpart (ST-G), a two-tier system based on mitotic count alone, in a cohort of 133 patients [59 female, 74 male; mean age 54 years (range 20-87)] with meningeal SFT/HPC. Tumors were pathologically confirmed through review of the first tumor resection (n = 97), local recurrence (n = 35), or distant metastasis (n = 1). A STAT6 immunostain showed nuclear expression in 132 cases. NAB2-STAT6 fusion was detected in 99 of 111 successfully tested tumors (89%) including the single STAT6 immunonegative tumor. Tumors were classified by CNS-G as grade 1 (n = 43), 2 (n = 41), or 3 (n = 49), and by ST-G as SFT (n = 84) or malignant SFT (n = 49). Necrosis was present in 16 cases (12%). On follow-up, 42 patients had at least one subsequent recurrence or metastasis (7 metastasis only, 33 recurrence only, 2 patients had both). Twenty-nine patients died. On univariate analysis, necrosis (p = 0.002), CNS-G (p = 0.01), and ST-G (p = 0.004) were associated with recurrence-free (RFS) but not overall survival (OS). NAB2-STAT6 fusion type was not significantly associated with RFS or OS, but was associated with phenotype. A modified ST-G incorporating necrosis showed higher correlation with RFS (p = 0.0006) and remained significant (p = 0.02) when considering only the primary tumors. From our data, mitotic rate and necrosis appear to stratify this family of tumors most accurately and could be incorporated in a future grading scheme

Exposición al SARS-CoV-2 y la percepción del riesgo de los trabajadores en entornos no sanitarios de Hong Kong, Nanjing y Wuhan: Un estudio cualitativo multisitio

Introducción: Understanding risk perception that hinges on health-protective behaviors is central to strategies for prevention. Aim: To classify the pattern of potential risk of worker exposure to SARS-CoV-2, and to assess association with risk perception among non-healthcare workers Methods: In a multi-site, qualitative study, we conducted individual in-depth interviews and mini focus group discussions with employees, managerial staff and self-employees from Hong Kong (n=87), Nanjing (n=60), and Wuhan (n=60) between June 2020 and March 2021. Audios were transcribed and categorized by themes following Grounded Theory approach. Results: We identified seven major types of potential risk exposure pattern by category of parameters. The risk perceptions decreased among Type A workers, working at fixed location in office, and no/little contacts with clients/customers, and increased among workers having the concern of asymptomatic characteristics of SAR-CoV-2, daily contact with large size of the unfamiliar crowds, unhygienic behaviors of clients/customers, and use of public transportation to commute to work. The notion that the sense of safety deriving from the implementation and adherence with safety measures despite stringency, and trust with the government was most frequently reported in Nanjing and Wuhan. Conclusion: Study examines COVID-19 risks and risk perceptions among non-healthcare workers in three cities. Variations in risk perceptions were found, influenced by factors such as work patterns and safety measures. Trust in government and concerns about international contacts were common themes. The findings emphasize the need for targeted interventions, mental health support, and inclusive policies to address occupational health disparities and promote workplace safety.Introducción: Comprender la percepción del riesgo que condiciona conductas de protección de la salud es fundamental para la prevención. Objetivo: Clasificar el patrón del riesgo de exposición de los trabajadores al SRAS-CoV-2 y su asociación con la percepción del riesgo entre los trabajadores no sanitarios. Métodos: Estudio cualitativo multisitio. Realizamos entrevistas en profundidad y minigrupos de discusión con empleados, personal directivo y autoempleados de Hong Kong (n=87), Nanjing (n=60) y Wuhan (n=60) -junio 2020-marzo 2021-. Los audios se transcribieron y clasificaron por temas con enfoque de la teoría fundamentada. Resultados: Se identificaron siete tipos de patrón de exposición (Tipo A-G) al riesgo potencial. Las percepciones de riesgo disminuyeron entre trabajadores de tipo A que trabajaban en oficina y sin contacto con clientes y aumentaron entre trabajadores preocupados por características asintomáticas del SAR-CoV-2, contacto diario con multitudes, comportamientos antihigiénicos de clientes y uso de transporte público para ir al trabajo. La sensación de seguridad por aplicación y cumplimiento de medidas de seguridad y la confianza en el gobierno fue más frecuente en Nanjing y Wuhan. Conclusiones: Se hallaron variaciones en las percepciones del riesgo, influidas por factores como pautas de trabajo y medidas de seguridad. Fueron comunes la confianza en el gobierno y la preocupación por los contactos internacionales. Se requieren intervenciones específicas, apoyo a la salud mental y políticas integradoras para abordar las disparidades en salud laboral y promover la seguridad en el lugar de trabajo

Influence of the peritoneal lavage with bupivacaine on the survival and resistance of colonic anastomoses performed under fecal peritonitis in rats

PURPOSE: To evaluate the effects of peritoneal lavage with bupivacaine on survival and initial resistance of anastomosis on distal colon, performed under peritonitis or not. METHODS: Forty rats, weighing from 300 to 350g (321.29±11.31g), were randomly divided in four groups and underwent laparotomy and anastomosis on the distal colon six hours after induction of peritonitis by intraperitoneal injection of autologous fecal material or not. Group 1: No peritonitis and lavage with 3ml NS; Group 2: No peritonitis and lavage with 8 mg.kg-1 (± 0.5 mL) of 0.5% bupivacaine added to 2.5 mL of NS; Group 3: Peritonitis and lavage with 3ml NS; Group 4: Peritonitis and lavage with 8 mg.kg-1 (± 0.5 mL) of 0.5% bupivacaine added to 2.5 mL of NS. Necropsies were performed on the animals that died and the time of death was recorded. Surviving animals were submitted to euthanasia on the fifth post-operative day and Total Energy of Rupture biomechanical test (TER) was applied. RESULTS: Group 4 showed survival increase compared to Group 3, without statistical significance. Group 3 presented the smallest average TER, with statistical significance. CONCLUSION: Peritonitis increased mortality and influenced negatively the resistance of colic anastomosis in rats. Peritoneal lavage with bupivacaine increased anastomotic resistance.78378