26 research outputs found

    Preroughening, Diffusion, and Growth of An FCC(111) Surface

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    Preroughening of close-packed fcc(111) surfaces, found in rare gas solids, is an interesting, but poorly characterized phase transition. We introduce a restricted solid-on-solid model, named FCSOS, which describes it. Using mostly Monte Carlo, we study both statics, including critical behavior and scattering properties, and dynamics, including surface diffusion and growth. In antiphase scattering, it is shown that preroughening will generally show up at most as a dip. Surface growth is predicted to be continuous at preroughening, where surface self-diffusion should also drop. The physical mechanism leading to preroughening on rare gas surfaces is analysed, and identified in the step-step elastic repulsion.Comment: Revtex + uuencoded figures, to appear in Physical Review Letter

    Aging in multiple sclerosis: from childhood to old age, etiopathogenesis, and unmet needs: a narrative review

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    Multiple sclerosis (MS) primarily affects adult females. However, in the last decades, rising incidence and prevalence have been observed for demographic extremes, such as pediatric-onset MS (POMS; occurring before 18 years of age) and late-onset MS (corresponding to an onset above 50 years). These categories show peculiar clinical-pathogenetic characteristics, aging processes and disease courses, therapeutic options, and unmet needs. Nonetheless, several open questions are still pending. POMS patients display an important contribution of multiple genetic and environmental factors such as EBV, while in LOMS, hormonal changes and pollution may represent disease triggers. In both categories, immunosenescence emerges as a pathogenic driver of the disease, particularly for LOMS. In both populations, patient and caregiver engagement are essential from the diagnosis communication to early treatment of disease-modifying therapy (DMTs), which in the elderly population appears more complex and less proven in terms of efficacy and safety. Digital technologies (e.g., exergames and e-training) have recently emerged with promising results, particularly in treating and following motor and cognitive deficits. However, this offer seems more feasible for POMS, being LOMS less familiar with digital technology. In this narrative review, we discuss how the aging process influences the pathogenesis, disease course, and therapeutic options of both POMS and LOMS. Finally, we evaluate the impact of new digital communication tools, which greatly interest the current and future management of POMS and LOMS patients

    Disordered Flat Phase and Phase Diagram for Restricted Solid on Solid Models of Fcc(110) Surfaces

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    We discuss the results of a study of restricted solid-on-solid models for fcc (110) surfaces. These models are simple modifications of the exactly solvable BCSOS model, and are able to describe a (2Ă—1)(2\times 1) missing-row reconstructed surface as well as an unreconstructed surface. They are studied in two different ways. The first is by mapping the problem onto a quantum spin-1/2 one-dimensional hamiltonian of the Heisenberg type, with competing SizSjzS^z_iS^z_j couplings. The second is by standard Monte Carlo simulations. We find phase diagrams with the following features, which we believe to be quite generic: (i) two flat, ordered phases (unreconstructed and missing-row reconstructed); a rough, disordered phase; an intermediate disordered flat (DF) phase, characterized by monoatomic steps, whose physics is shown to be akin to that of a dimer spin state. (ii) a transition line from the (2Ă—1)(2\times 1) reconstructed phase to the DF phase showing exponents which appear to be close, within our numerical accuracy, to the 2D-Ising universality class. (iii) a critical (preroughening) line with variable exponents, separating the unreconstructed phase from the DF phase. Possible signatures and order parameters of the DF phase are investigated.Comment: Revtex (22 pages) + 15 figures (uuencoded file

    Aging in multiple sclerosis: from childhood to old age, etiopathogenesis, and unmet needs: a narrative review

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    Multiple sclerosis (MS) primarily affects adult females. However, in the last decades, rising incidence and prevalence have been observed for demographic extremes, such as pediatric-onset MS (POMS; occurring before 18 years of age) and late-onset MS (corresponding to an onset above 50 years). These categories show peculiar clinical-pathogenetic characteristics, aging processes and disease courses, therapeutic options, and unmet needs. Nonetheless, several open questions are still pending. POMS patients display an important contribution of multiple genetic and environmental factors such as EBV, while in LOMS, hormonal changes and pollution may represent disease triggers. In both categories, immunosenescence emerges as a pathogenic driver of the disease, particularly for LOMS. In both populations, patient and caregiver engagement are essential from the diagnosis communication to early treatment of disease-modifying therapy (DMTs), which in the elderly population appears more complex and less proven in terms of efficacy and safety. Digital technologies (e.g., exergames and e-training) have recently emerged with promising results, particularly in treating and following motor and cognitive deficits. However, this offer seems more feasible for POMS, being LOMS less familiar with digital technology. In this narrative review, we discuss how the aging process influences the pathogenesis, disease course, and therapeutic options of both POMS and LOMS. Finally, we evaluate the impact of new digital communication tools, which greatly interest the current and future management of POMS and LOMS patients

    Una vocazione alla libertĂ  (comunista)

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    1. Ho letto qualche libro, non conosco tutti gli interventi “tendenziosi” e non posso attribuire a tutti o ad alcuni un unico disegno politico-culturale e un’unica finalità. Posso sospettare, in alcuni, il malcelato tentativo di “attualizzare” Gramsci come post-comunista e (neo)liberale.   2. Francesca Chiarotto (2011 e in vari interventi successivi) ha ricostruito con attenzione le varie e, in molti casi, arbitrarie opinioni sui rapporti tra i due compagni e amici. Il contrasto Gramsci-Togli..

    Réflexions sur l'ontologie de Lukács

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    Prestipino Giuseppe. Réflexions sur l'ontologie de Lukács. In: L'Homme et la société, N. 79-82, 1986. Lukács-Bloch : raison et utopie. pp. 127-137

    À propos du Manifeste de 1848

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    Self-Assembled Structures of Colloidal Dimers and Disks on a Spherical Surface

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    We study self-assembly on a spherical surface of a model for a binary mixture of amphiphilic dimers in the presence of guest particles via Monte Carlo (MC) computer simulation. All particles had a hard core, but one monomer of the dimer also interacted with the guest particle by means of a short-range attractive potential. We observed the formation of aggregates of various shapes as a function of the composition of the mixture and of the size of guest particles. Our MC simulations are a further step towards a microscopic understanding of experiments on colloidal aggregation over curved surfaces, such as oil droplets

    Analysis of citrus peels-based polygeneration plant for hydrogen, heat, power and DME production: energy and exergy analysis

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    The energy sustainability of producing biofuel from wet bioresidues needs proper energy integration to ensure sustainable exploitation. This study analyses the potentials of combined hydrogen, heat, power, and LOHC (Liquid Organic Hydrogen Carrier) production from the residues of citrus juice production, at a factory scale. In this work, the main constituents of LOHC are DME (Dimethyl ether) and methanol. The proposed system is based on air-steam gasification and direct CO2-to-DME process, integrated with hydrogen purification and a CHP unit. The DME reactor is operated at 30 bar in the temperature range 493-533 K. A thermodynamic model, which is validated experimentally, simulates the proposed polygeneration system. In addition to the potential amount of biofuel, hydrogen production, and net power production, the energy and exergy efficiencies are analyzed. Despite the variation of LOHC yield with the temperature, the results show that the whole system’s energy efficiency is not affected, while the small difference among the exergy efficiencies is negligible
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