15 research outputs found

    Seasonal variability in public searches of keratosis pilaris: How the internet can illuminate a pattern in public interest.

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    In this study, we examine keratosis pilaris search patterns using Google Trends to determine any seasonality. Monthly searches were collected from January 2004 to January 2020 using keratosis pilaris as the search term in the Google Trends database. The US search data were compared to monthly temperatures and tested for correlation. Worldwide search interest was also acquired and, along with the US data, a two-model analysis was performed to determine any seasonal patterns. Peaks in search interest closely overlapped with higher temperatures in the United States and showed correlation (.44; P \u3c .0001). The US and worldwide search interest also exhibited seasonality, which was confirmed with a sinusoidal regression being the best-fit model (

    Herpes simplex laryngitis presenting as airway obstruction in a stroke patient

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    We present the second confirmed report of HSV laryngitis in an adult stroke patient, resulting in complicated airway management issues. This rare presentation of laryngeal HSV in a stroke patient can interfere with speech, language, and swallowing functions and confounds the etiology of these issues, which can impact subsequent management. Keywords: Herpes simplex virus, Laryngitis, Airway obstruction, Cerebrovascular accident, Voice/dysphoni

    Eye injuries in the National Hockey League from 2010 to 2018: an analysis of injury rates, mechanisms, and the National Hockey League visor policy.

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    OBJECTIVE: We aim to assess the efficacy of widespread visor adoption by assessing eye injury rates during the 2010-2018 seasons. We also compare injury rates, missed games, and financial losses to previously reported data in order to track progress over time. Lastly, we characterize the mechanism and type of eye injuries sustained by National Hockey League (NHL) players to examine risk areas within NHL games. DESIGN: We performed a retrospective review of NHL player injuries using official NHL team reports, ProSportsTransactions, and TSN Sports. PARTICIPANTS: All NHL players who suffered an eye injury from 2010 to 2018 were included; 31 injuries matched this criterion. METHODS: Trends in injuries, missed games, and financial losses over time were analyzed using Pearson\u27s correlation coefficients. Wilcoxon-Mann-Whitney tests were performed to compare our data with eye injury data. Fisher\u27s exact test was performed to assess significance between mechanism and type of eye injury and outcome. RESULTS: There were 31 total eye injuries causing 233 missed games and a total of US8951000infinanciallossesacrossthe20102018seasons.Therewasastrongdecreaseinthenumberofeyeinjuries(r=0.83,p=0.01)andamoderatedecreaseinnumberofmissedgames(r=0.62,p=0.09).InjuriesduetodirectpuckstrikescontributedtooverUS8 951 000 in financial losses across the 2010-2018 seasons. There was a strong decrease in the number of eye injuries (r = -0.83, p = 0.01) and a moderate decrease in number of missed games (r = -0.62, p = 0.09). Injuries due to direct puck strikes contributed to over US6.5 million in financial losses and led to significantly more missed games compared with stick injuries (14.6 vs 4.3). CONCLUSION: We tangibly demonstrate the financial and physical effects of recent safety interventions and indicate areas for improved safety in the NHL

    Ocular adnexal metastases from renal cell carcinoma: An update and comprehensive literature review

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    PURPOSE: The purpose of this study was to review the clinical presentation, systemic work-up, and outcomes of all previously reported ocular adnexal (OA) metastases from renal cell carcinoma (RCC). METHODS: This was a literature review. PubMed and Google Scholar databases were searched for all well-documented cases of OA metastases from RCC. RESULTS: Final analysis identified 44 patients with either biopsy-confirmed (41/44, 93%) or treatment response-documented (3/44, 6%) OA metastases from RCC. Thirty-four (77%) patients were male. The median age was 60 years (mean: 60, range: 22-87 years). The most common presenting signs were proptosis (19/44, 43%) and OA mass (14/44, 32%). Metastases most frequently involved the orbital bones (10/44, 23%) and adjacent extraconal fat, extending from the sinonasal tract in 7/10 (70%) of these cases. OA metastases were initial manifestation of RCC in 18/44 (41%) patients. At the time of primary tumor diagnosis, 22 of 30 (73%) patients had American Joint Committee on Cancer Stage IV disease with metastases to 2 or more sites in 13 (57%) patients. Seventeen of 42 (40%) patients underwent local therapy only, which most commonly included excision/exenteration with margin control (10/17, 59%). Twenty-five of 42 (60%) patients had systemic therapy, which included biologic agents and chemotherapy. The absolute 5-year survival rate was 66% with significantly improved survival in patients reported after 2006 (92% vs. 42%, P = 0.04) and in those with isolated OA metastases (100% vs. 27%, P = 0.02) at 30 months. CONCLUSION: Although RCC metastases to OA occur in a setting of advanced disease, the recent advances in diagnostic modalities and targeted therapies resulted in improved survival
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