Basic aspects of the pharmacodynamics of tolperisone, a widely applicable centrally acting muscle relaxant

Tolperisone (2-methyl-1-(4-methylphenyl)-3-piperidin-1-ylpropan-1-one hydro-chloride) was introduced in the clinical practice more than forty years ago and is still evaluated as a widely applicable compound in pathologically elevated skeletal muscle tone (spasticity) and related pains of different origin. In the present review, basic pharmacodynamic effects measured on whole animals, analyses of its actions on cell and tissue preparations and molecular mechanism of action on sodium and calcium channels are summarized as recently significantly new data were reported

STUDIES FOOD AND FEEDING HABITS, FOOD PREFERENCE AND FEEDING MECHANISM IN THE MILLIPEDE JONESPELTIS SPLEDIDUS VERHOEFF IN CAPTIVITY

The adults of J. splentidus Verhoeff when offered leaf litter in different stages of decay, accepted only the litter in its advanced stage of decay. They showed preference to a few species of litter from the ten different species of plants offered, specifically the litters of Artocarpus, Terminalia and Macaranga. The litter of plants tested include Anacardium and Eucalyptus which contains well known secondary plant substances. When sugar and poly phenol content of fresh litter was estimated, it was found that the preferred litter was having comparatively a very low polyphe­nol content and high percentage of sugar. The morphology of mouth parts and the feeding mechanism of the animal were also noted

Two new Records of Soil Collembola from South India

Volume: 70Start Page: 572End Page: 57