Salivary Anionic Changes after Radiotherapy for Nasopharyngeal Carcinoma: A 1-Year Prospective Study

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Novel geometric coordination registration in cone-beam computed tomogram

Paper ID: AIPR-140701-9The use of cone-beam computed tomography (CBCT) in medical field can help the clinicians to visualize the hard tissues in head and neck region via a cylindrical field of view (FOV). The images are usually presented with reconstructed three-dimensional (3D) imaging and its orthogonal (x-, y-and z-planes) images. Spatial relationship of the structures in these orthogonal views is important for diagnosis of diseases as well as planning for treatment. However, the non-standardized positioning of the object during the CBCT data acquisition often induces errors in measurement since orthogonal images cut at different planes might look similar. In order to solve the problem, this paper proposes an effective mapping from the Cartesian coordinates of a cube physically to its respective coordinates in 3D imaging. Therefore, the object (real physical domain) and the imaging (computerized virtual domain) can be linked up and registered. In this way, the geometric coordination of the object/imaging can be defined and its orthogonal images would be fixed on defined planes. The images can then be measured with vector information and serial imagings can also be directly compared. © 2014 IEEE.published_or_final_versio

Effects of calcium phosphate nanocrystals on osseointegration of titainium implant in irradiated bone

Radiotherapy may compromise the integration of implant and cause implant loss. Implant surface modifications have the possibility of promoting cell attachment, cell growth, and bone formation which ultimately enhance the osseointegration process. The present study aimed to investigate the effects of calcium phosphate nanocrystals on implant osseointegration in irradiated bone. Sixteen rabbits were randomly assigned into control and nano-CaP groups, receiving implants with dual acid-etched surface or dual acid-etched surface discretely deposited of nanoscale calcium-phosphate crystals, respectively. The left leg of all the rabbits received 15 Gy radiation, followed by implants placement one week after. Four animals in each group were sacrificed after 4 and 12 weeks, respectively. Implant stability quotient (ISQ), ratio of bone volume to total volume (BV/TV), bone growth rate, and bone-to-implant contact (BIC) were evaluated. The nano-CaP group showed significantly higher ISQ (week 12, P = 0.031) and bone growth rate (week 6, P = 0.021; week 9, P = 0.001) than that in control group. No significant differences in BV/TV and BIC were found between two groups. Titanium implant surface modified with CaP nanocrystals provides a potential alternative to improve bone healing around implant in irradiated bone.published_or_final_versio

Validation of a novel geometric coordination registration using manual and semi-automatic registration in cone-beam computed tomogram

Session - Image Processing: Machine Vision Applications 9Cartesian coordinates define on a physical cubic corner (CC) with the corner tip as the origin and three corresponding line angles as (x, y, z)-axes. In its image (virtual) domains such as these obtained by cone-beam computed tomography (CBCT) and optical surface scanning, a single coordinate can then be registered based on the CC. The advantage of using a CC in registration is simple and accurate physical coordinate measurement. The accuracy of image-to-physical (IP) and imageto-image (II) transformations, measured by target registration error (TRE), can then be validated by comparing coordinates of target points in the virtual domains to that of the physical control. For the CBCT, the registration may be performed manually using a surgical planning software SimPlant Pro (manual registration (MR)) or semi-automatically using MeshLab and 3D Slicer (semiautomatic registration (SR)) matching the virtual display axes to the corresponding (x-y-z)-axes. This study aims to validate the use of CC as a surgical stereotactic marker by measuring TRE in MR and SR respectively. Mean TRE is 0.56 +/- 0.24 mm for MR and 0.39 +/- 0.21 mm for SR. The SR results in a more accurate registration than the MR and point-based registration with 20 fiducial points. TRE of the MR is less than 1.0 mm and still acceptable clinically.postprin

Oral perception/motor ability in edentulous patients with stroke and Parkinsonism

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Psychosocial and quality of life outcomes of prosthetic auricular rehabilitation with CAD/CAM technology.

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Oral yeast colonization in southern Chinese nasopharyngeal carcinoma survivors

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Oral yeast profile in nasopharyngeal carcinoma patients following adjuvant chemotherapy

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Reduced level of induced endocytosis in Candida albicans sap7 mutants

Poster Session: Scientific Groups - 90. Microbiology/Immunology III: no. 655OBJECTIVE: To investigate the effect of C. albicans SAP7 gene in induced endocytosis in Candida-epithelial cell interactions. METHOD: In this study, C. albicans sap7 mutant strain was constructed in our laboratory by a PCR – based gene disruption method. In the endocytosis assay, the number of C. albicans cells that were cell-associated with and endocytosed by OKF6/TERT2 was determined using differential fluorescence assay with minor modifications. Briefly, conflucent OKF6/TERT2 cells were infected with 1×105 Candida cells for 3 h incubation. After removing nonadherent organisms, the cells were fixed with 3% paraformaldehyde. The adherent but not endocytosed ...postprin

Quality of life following intensity-modulated radiotherapy for nasopharyngeal carcinoma

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