20 research outputs found
Intermediary inflammatory reaction after micropulse cyclophotocoagulation diode therapy: a case report.
No full textOf the many types of laser cyclophotocoagulation procedures, micropulse cyclophotocoagulation diode is praised as a noninvasive, safe, and effective procedure with few complications. In this case report, we describe a rare complication that, to the best of our knowledge, has not been previously reported. We report on the case of a 66-year-old African man with a history of end-stage primary open-angle glaucoma. One week after undergoing micropulse cyclophotocoagulation diode therapy in both eyes, he developed severe intermediary inflammation in one eye, associated with decreased visual acuity. The intraocular pressure had significantly decreased after the procedure and was well controlled with intraocular-pressure-lowering medications. Slit lamp examination revealed a moderate anterior chamber inflammation, anterior vitritis, and a large inflammatory membrane attached to the posterior surface of the intraocular implant. A vitrectomy was finally performed in the left eye because of the persistent intermediary inflammation despite the use of high doses of topical and subconjunctival corticosteroids. Intermediary uveitis is a rare complication after micropulse cyclophotocoagulation diode therapy. To the best of our knowledge, there have been no reports of vitritis after a noncomplicated micropulse cyclophotocoagulation diode in primary open-angle glaucoma
Effect of topical corneal anaesthesia on ocular response analyzer parameters: pilot study.
No full textThe effect of topical corneal anaesthesia on corneal hysteresis (CH), corneal resistance factor (CRF), Goldmann-correlated intraocular pressure (IOPg), and corneal compensated IOP (IOPcc) was measured by ocular response analyzer (ORA).Journal ArticleSCOPUS: ar.jinfo:eu-repo/semantics/publishe
Evaluation of corneal biomechanical properties with the Reichert Ocular Response Analyzer.
No full textPurpose. To compare corneal hysteresis (CH) and corneal resistance factor (CRF) measured with the Ocular Response Analyzer (ORA) in patients with primary open-angle glaucoma (POAG), patients with ocular hypertension (OHT), and normal subjects (NL); and to assess correlations of CH and CRF with corneal-compensated intraocular pressure (IOPcc), Goldmann applanation tonometry (GAT), glaucoma type, central corneal thickness (CCT), previous filtering procedure, and antiglaucoma medications. Methods. A total of 108 POAG, 22 OHT, and 24 NL were enrolled in this observational study. Goldmann applanation tonometry and ORA were performed in a randomized sequence followed by pachymetry. One eye per subject was selected at random for analysis. Chi-square, Wilcoxon, and Kruskal-Wallis tests were used for comparison and Spearman coefficient for assessing correlations. Results. Mean CH and CRF were significantly lower in POAG than in OHT and NL. Ocular Response Analyzer IOPcc overestimated IOP compared to GAT only in POAG. This difference increased with higher GAT. Goldmann applanation tonometry and IOPcc were correlated. Corneal hysteresis was negatively correlated with age in POAG. Corneal resistance factor and CH were positively correlated with CCT in POAG and OHT. Unlike CRF, CH was not correlated with GAT in POAG and OHT. Corneal-compensated intraocular pressure was not correlated with CCT. Difference between GAT and IOPcc was not CCT dependent. Corneal hysteresis and CRF were comparable in POAG and NTG, unchanged after filtering procedure. Corneal hysteresis was not altered by topical medications. Corneal resistance factor was significantly lower in treated eyes and those receiving prostaglandin analogues with no correlation with the treatment duration. Conclusions. Patients with glaucoma seem to have distinctive corneal biomechanical properties compared to OHT and NL. They may be influenced by many other unknown subparameters
Influence of corneal hysteresis on glaucomatous visual field damage.
No full textinfo:eu-repo/semantics/nonPublishe
Analyse de la papille glaucomateuse :avec ou sans champ visuel
No full textinfo:eu-repo/semantics/nonPublishe
Corrélation entre hystérèse cornéenne, facteur de résistance cornéen et amplitude de pulsation oculaire chez les sujets sains
No full textPurpose: The Ocular Response Analyzer (ORA®) measures corneal biomechanical properties: corneal hysteresis (CH) and the corneal resistance factor (CRF). The Pascal Dynamic Contour Tonometer (PDCT) measures the ocular pulse amplitude (OPA), which represents the systolic-diastolic variation in intraocular pressure (IOP). Both ORA® and OPA values are lower in glaucoma patients than in normal patients. Our purpose was to assess whether there is a correlation between CH, CRF, and OPA values in healthy subjects. Design and participants: Prospective observational study including 81 eyes of 41 healthy adult volunteers. Patients with ocular eye disease, previous refractive or intraocular surgery, contact lenses, or topical or general medications were excluded. Methods: Patients underwent four ORA, three OPA, and two Goldmann Applanation Tonometry (GAT) measurements. For each device, the mean of all measurements were considered for this study. The statistical analysis by Spearman rank correlations was performed for right (RE), left (LE), and both eyes. The correlation between the two eyes of each subject was taken into account and canonical correlations were calculated using the SAS statistical software to improve the power of the analysis. Results: The mean age was 43.6 ± 14.6 years. The mean central corneal thickness was 545 ± 32 μm for RE, 553 ± 34 μm for LE, and 550 ± 32 μm for both eyes. The mean IOP(GAT) values for RE, LE, and both eyes were, respectively 14.3 ± 2.9 mmHg, 14.0 ± 2.9 mmHg, and 14.2 ± 2.9 mmHg. Spearman correlations were not statistically significant for separated RE and LE analysis. For both eyes, these correlations were r(S) = 0.210, p = 0.193 for OPA/CH and r(S) = 0.388, p = 0.013 for OPA/CRF. The Spearman correlation was statistically significant for OPA/CRF. This result was confirmed by canonical correlations (p = 0.002) and in addition, CH was statistically correlated to OPA in the latter analysis (p = 0.010). Conclusion: A statistically significant correlation was found between corneal biomechanical property values as measured by ORA® and ocular pulse amplitude values as measured by PDCT in healthy subjects. © 2008. Elsevier Masson SAS.SCOPUS: ar.jinfo:eu-repo/semantics/publishe
Comparison of the corneal biomechanical properties with the Ocular Response Analyzer® (ORA) in African and Caucasian normal subjects and patients with glaucoma
No full textPURPOSE: To compare corneal hysteresis (CH) and corneal resistance factor (CRF) measured with the Ocular Response Analyzer(®) tonometer (ORA) between (i) African normals and treated primary open-angle glaucoma (POAG) patients and (ii) between normals and treated POAG Caucasians. To analyse the correlation of CH and CRF with visual field (VF) defects in the two groups.
METHODS: This comparative study included 59 African (29 (POAG), 30 normals) and 55 Caucasians (30 POAG and 25 normals) subjects. Goldmann applanation tonometry (GAT) and ORA measurements were performed in a randomized sequence. Visual field was tested with the Swedish interactive threshold algorithms standard strategy of the Humphrey perimeter. Hoddap classification was used to estimate the severity of VF defects.
RESULTS: Primary open-angle glaucoma Africans were younger than POAG Caucasians (p < 0.001). Goldmann applanation tonometry and central corneal thickness (CCT) did not differ significantly between the four subgroups. African normals had lower CH than Caucasian controls (p < 0.001). CH was 9.2 ± 1.1 and 8.3 ± 1.7 mmHg respectively in POAG Caucasians and Africans (p < 0.001). African controls had higher ORA corneal-compensated intraocular pressure (IOPcc) than Caucasian controls (p < 0.001). Primary open-angle glaucoma Africans had higher IOPcc values than Caucasian POAGs (p < 0.001). CH and IOPcc were associated with race (p < 0.001) but not with CCT. Based on mean deviation values (MD), POAG Africans had more severe VF defects. CH was correlated with MD (r = 0.442; p = 0.031) and severity of VF defects only in POAG Africans (r = -0.464; p = 0.013).
CONCLUSIONS: African normal subjects and POAG patients had an altered CH, which is associated with a significant underestimation of GAT IOP. This may potentially contribute to the earlier development and greater severity of glaucoma damage in Africans compared with Caucasians at diagnosis
