MICROWAVE ASSISTED GREEN SYNTHESIS OF PHARMACEUTICALLY IMPORTANT DIHYDROPYRIMIDINONES IN FRUIT JUICE MEDIUM

Objective: The objective of this research project was to perform the green synthesis of a series of Dihydropyrimidinone (DHPM) derivatives which are having immense importance in biological and pharmaceutical science, via microwave assisted Biginelli reaction in fruit juice medium.Methods: Urea and ethyl acetoacetate were made to react with different electron rich as well as electron deficient aromatic aldehydes in various fruit juice medium under microwave irradiation. After successful completion of the reaction the crude product was precipitated out of the reaction medium and after re-crystallization of the crude product the pure desired DHPMs were obtained with quite good percentage of yield.Results: It was observed that our green Biginelli reaction was completed successfully within few minutes duration and the microwave assisted Biginelli reaction in fruit juice medium was much faster, greener and cleaner compared to that of room temperature Biginelli reaction in the same fruit juice medium. The acidity of the fruit juices and the electronic effect of the aromatic aldehydes have shown significant influence on the rate of reaction.Conclusion: Thus an efficient, green, cost-effective and eco-friendly method has been developed and reported for the very first time for microwave assisted synthesis of dihydropyrimidinone using some common fruit juices as reaction medium. The fruit juices have served as the solvent cum catalyst in these Biginelli reactions. Our current approach of synthesizing DHPM via microwave assisted Biginelli reaction in fruit juice medium has given a new direction in the field of green chemistry.Â

VISIBLE WATERMARKING WITHIN THE REGION OF NON-INTEREST OF MEDICAL IMAGES BASED ON FUZZY C-MEANS AND HARRIS CORNER DETECTION

Transfer of medical information amongst various hospitals and diagnostic centers for mutual availability of diagnostic and therapeutic case studies is a very common process. Watermarking is adding “ownership ” information in multimedia contents to verify signal integrity, prove authenticity and achieve control over the copy process. Distortion in Region of Interest (ROI) of a bio-medical image caused by watermarking may lead to wrong diagnosis and treatment. Therefore, proper selection of Region of Non-Interest (RONI) in a medical image is very crucial for adding watermark. First part of the present work proposes proper selection of Region of Non-Interest based on Fuzzy C-Means segmentation and Harris corner detection, to improve retention of diagnostic value lost in embedding ownership information. The second part of the work presents watermark embedding in the selected area of RONI based on alpha blending technique. In this approach, the generated watermarked image having an acceptable level of imperceptibility and distortion is compared to the original image. The Peak Signal to Noise Ratio (PSNR) of the original image vs. watermarked image is calculated to prove the efficacy of the proposed method

Abstracts of National Conference on Research and Developments in Material Processing, Modelling and Characterization 2020

This book presents the abstracts of the papers presented to the Online National Conference on Research and Developments in Material Processing, Modelling and Characterization 2020 (RDMPMC-2020) held on 26th and 27th August 2020 organized by the Department of Metallurgical and Materials Science in Association with the Department of Production and Industrial Engineering, National Institute of Technology Jamshedpur, Jharkhand, India. Conference Title: National Conference on Research and Developments in Material Processing, Modelling and Characterization 2020Conference Acronym: RDMPMC-2020Conference Date: 26–27 August 2020Conference Location: Online (Virtual Mode)Conference Organizer: Department of Metallurgical and Materials Engineering, National Institute of Technology JamshedpurCo-organizer: Department of Production and Industrial Engineering, National Institute of Technology Jamshedpur, Jharkhand, IndiaConference Sponsor: TEQIP-