Bosonic topological insulator intermediate state in the superconductor-insulator transition

A low-temperature intervening metallic regime arising in the two-dimensional superconductor-insulator transition challenges our understanding of electronic fluids. Here we develop a gauge theory revealing that this emergent anomalous metal is a bosonic topological insulator where bulk transport is suppressed by mutual statistics interactions between out-of-condensate Cooper pairs and vortices and the longitudinal conductivity is mediated by symmetry-protected gapless edge modes. We explore the magnetic-field-driven superconductor-insulator transition in a niobium titanium nitride device and find marked signatures of a bosonic topological insulator behavior of the intervening regime with the saturating resistance. The observed superconductor-anomalous metal and insulator-anomalous metal dual phase transitions exhibit quantum Berezinskii-Kosterlitz-Thouless criticality in accord with the gauge theory

A Systematic Review and Meta-Analysis to Inform Cancer Screening Guidelines in Idiopathic Inflammatory Myopathies

OBJECTIVES: To identify clinical factors associated with cancer risk in the idiopathic inflammatory myopathies (IIMs) and to systematically review the existing evidence related to cancer screening. METHODS: A systematic literature search was carried out on Medline, Embase and Scopus. Cancer risk within the IIM population (i.e. not compared to the general population) was expressed as risk ratios (RR) for binary variables and weighted mean differences (WMD) for continuous variables. Evidence relating to cancer screening practices in the IIMs were synthesised via narrative review. RESULTS: Sixty nine studies were included in the meta-analysis. Dermatomyositis subtype (RR 2.21), older age (WMD 11.19), male gender (RR 1.53), dysphagia (RR 2.09), cutaneous ulceration (RR 2.73), and anti-transcriptional intermediary factor-1 gamma positivity (RR 4.66) were identified as being associated with significantly increased risk of cancer. Polymyositis (RR 0.49) and clinically amyopathic dermatomyositis (RR 0.44) subtypes, Raynaud's phenomenon (RR 0.61), interstitial lung disease (RR 0.49), very high serum creatine kinase (WMD -1189.96) or lactate dehydrogenase (WMD -336.52) levels, and anti-Jo1 (RR 0.45) or anti-EJ (RR 0.17) positivity were identified as being associated with significantly reduced risk of cancer. Nine studies relating to IIM-specific cancer screening were included. Computed tomography (CT) scanning of the thorax, abdomen and pelvis appeared to be effective in identifying underlying asymptomatic cancers. DISCUSSION: Cancer risk factors should be evaluated in patients with IIM for risk stratification. Screening evidence is limited but CT scanning could be useful. Prospective studies and consensus guidelines are needed to establish cancer screening strategies in IIM patients

Superconducting phase transitions in ultrathin TiN films

Building on the complete account of quantum contributions to conductivity, we demonstrate that the resistance of thin superconducting films exhibits a non-monotonic temperature behaviour due to the competition between weak localization, electron-electron interaction, and superconducting fluctuations. We show that superconducting fluctuations give rise to an appreciable decrease in the resistance even at temperatures well exceeding the superconducting transition temperature, Tc, with this decrease being dominated by the Maki-Thompson process. The transition to a global phase-coherent superconducting state occurs via the Berezinskii-Kosterlitz-Thouless (BKT) transition, which we observe both by power-law behaviour in current-voltage characteristics and by flux flow transport in the magnetic field. The ratio TBKT/Tc follows the universal relation

Direct probe of the interior of an electric pion in a Cooper pair superinsulator

The nature of hadrons is one of the most fundamental mysteries of physics. It is generally agreed that they are made of "colored" quarks, which move nearly free at short scales but are confined inside hadrons by strong interactions at large distances. Because of confinement, quarks are never directly observable and, experimentally, their properties can be tested only indirectly, via high energy collisions. Here we show that superinsulating films realize a complete, one-color model system of hadron physics with Cooper pairs playing the role of quarks. We report measurements on highly controlled NbTiN films that provide a window into the interior of "Cooper pair mesons" and present the first direct evidence of asymptotic freedom, `t Hooft's dual superconductivity confinement mechanism, and magnetic monopoles

Superconducting phase transitions in ultrathin TiN films

We investigate transition to the superconducting state in the ultrathin titanium nitride films on approach to superconductor-insulator transition. Building on the complete account of quantum contributions to conductivity, we demonstrate that the resistance of thin superconducting films exhibits a non-monotonic temperature behaviour due to the competition between weak localization, electron-electron interaction, and superconducting fluctuations. We show that superconducting fluctuations give rise to an appreciable decrease in the resistance even at temperatures well exceeding the superconducting transition temperature, T_c, with this decrease being dominated by the Maki-Thompson process.The transition to a global phase-coherent superconducting state occurs via the Berezinskii-Kosterlitz-Thouless (BKT) transition, which we observe both by power-law behaviour in current-voltage characteristics and by flux flow transport in the magnetic field. The ratio T_{BKT}/T_c follows the universal Beasley-Mooij-Orlando relation. Our results call for revisiting the past data on superconducting transition in thin disordered films.Comment: 6 pages, 4 figure