71 research outputs found

    Biogenetically-Inspired Total Synthesis of Epidithiodiketopiperazines and Related Alkaloids

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    Natural products chemistry has historically been the prime arena for the discovery of new chemical transformations and the fountain of insights into key biological processes. It remains a fervent incubator of progress in the fields of chemistry and biology and an exchange mediating the flow of ideas between these allied fields of science. It is with this ethos that our group has taken an interest in and pursued the synthesis of a complex family of natural products termed the dimeric epipolythiodiketopiperazine (ETP) alkaloids. We present here an Account of the highly complex target molecules to which we pegged our ambitions, our systematic and relentless efforts toward those goals, the chemistry we developed in their pursuit, and the insight we have gained for their translational potential as potent anticancer molecules.National Institute of General Medical Sciences (U.S.) (Grant GM089732)Amgen Inc

    Bestimmung der elektrischen Leitfaehigkeit eines Argon-Hochdruckplasmas aus Messungen am Kaskadenboden

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    79 refs.SIGLECopy held by FIZ Karlsruhe; available from UB/TIB Hannover / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekDEGerman

    Polymer optical fibers for short-shorter and shortest data links

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    Polymer Optical fibers combine the advantages of an optical communication medium with the availability of low cost components and extremely easy installation. After the introduction of POF in car networks the use in building networks will be the next big market. Interdevice data links and sensor networks are additional potential fields of application. Improved active components and the use of efficient coding schemes will open new possibilities for optical data communication in a distance range between centimeters and several 100 meters

    Fluoreszenzeigenschaften optischer Fasern Abschlussbericht

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    SIGLEAvailable from TIB Hannover: F00B1265 / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekBundesministerium fuer Bildung, Wissenschaft, Forschung und Technologie, Bonn (Germany)DEGerman

    Lichtleitfasern

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    Copy held by FIZ Karlsruhe; available from UB/TIB Hannover / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEDEGerman

    Low cost fiberoptic gyroscope

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    SIGLECopy held by FIZ Karlsruhe; available from UB/TIB Hannover / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekDEGerman

    Buchbesprechungen

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