Tailored point-of-care biosensors for liquid biopsy in the field of oncology

In the field of cancer detection, technologies to analyze tumors using biomarkers circulating in fluids such as blood have developed rapidly based on liquid biopsy. A proactive approach to early cancer detection can lead to more effective treatments with minimal side effects and better long-term patient survival. However, early detection of cancer is hindered by the existing limitations of conventional cancer diagnostic methods. To enable early diagnosis and regular monitoring and improve automation, the development of integrated point-of-care (POC) and biosensors is needed. This is expected to fundamentally change the diagnosis, management, and monitoring of response to treatment of cancer. POC-based techniques will provide a way to avoid complications that occur after invasive tissue biopsy, such as bleeding, infection, and pain. The aim of this study is to provide a comprehensive view of biosensors and their clinical relevance in oncology for the detection of biomarkers with liquid biopsies of proteins, miRNA, ctDNA, exosomes, and cancer cells. The preceding discussion also illustrates the changing landscape of liquid biopsy-based cancer diagnosis through nanomaterials, machine learning, artificial intelligence, wearable devices, and sensors, many of which apply POC design principles. With the advent of sensitive, selective, and timely detection of cancer, we see the field of POC technology for cancer detection and treatment undergoing a positive paradigm shift in the foreseeable future

Unusual Metastases to Diaphragm and Spleen from Adenocarcinoma of Lung Detected by 18F-FDG PET/CT Imaging: A Case Report

Globally, carcinoma of lung is the predominant cause of cancer deathamong both men and women. While hematogenous spread from primarylung cancer to multiple other organs is frequently reported, metastases ofmalignant tumors to diaphragm and spleen are rare. Nowadays, Positronemission tomography (PET) with 18 F- fluorodeoxyglucose (FDG) hasemerged in such a way that it has become an effective imaging technology for the evaluation of different carcinomas, particularly for cancerstaging and follow up after therapy. PET scan is able to provide metabolicinformation. In this case, we present an attractive unified PET/CT scanimage in a patient with lung carcinoma having unusual diaphragm andsplenic metastases. So, PET/CT imaging could strongly identified rareand unusual metastatic sites of cancer and added more appropriate stagingin patient with carcinoma of lung

Abstracts of 1st International Conference on Machine Intelligence and System Sciences

This book contains the abstracts of the papers presented at the International Conference on Machine Intelligence and System Sciences (MISS-2021) Organized by the Techno College of Engineering, Agartala, Tripura, India & Tongmyong University, Busan, South Korea, held on 1–2 November 2021. This conference was intended to enable researchers to build connections between different digital technologies based on Machine Intelligence, Image Processing, and the Internet of Things (IoT). Conference Title: 1st International Conference on Machine Intelligence and System SciencesConference Acronym: MISS-2021Conference Date: 1–2 November 2021Conference Location: Techno College of Engineering Agartala, Tripura(w), IndiaConference Organizer: Techno College of Engineering, Agartala, Tripura, India & Tongmyong University, Busan, South Korea