Guía ESC 2015 sobre el tratamiento de la endocarditis infecciosa

[No abstract available

Introducing a novel nanocomposite consisting of nitrogen-doped carbon nano-onions and gold nanoparticles for the electrochemical sensor to measure acetaminophen

In the present study, gold nanoparticles and nitrogen-doped carbon nano-onions (AuNP/NCNO) in a nanocomposite-based sensor were reported for the electrochemical detection of acetaminophen (APAP). The NCNOs from the fullerene family were prepared using a simple and cost-effective method using aminated nanodiamonds (AM-ND) as a substrate. Nitrogen atoms were introduced into CNO cages during the preparation of these nanostructures by annealing AM-NDs under an inert helium atmosphere and reduced pressure. AuNPs were synthesized using a straightforward method. The nanocomposite profoundly enhanced the active surface area of the glassy carbon electrode and amplified the electron transfer rate. Accordingly, electrocatalysis of the APAP was achieved at the modified electrode surface at 0.38 V vs. Ag/AgCl. Under the optimal conditions, the sensor displayed a linear response for APAP detection ranging from 25 nM to 35 mu M with a limit of detection (LOD) of 9 nM. Potentially interfering drugs, such as ascorbic acid and dopamine, with 5-fold higher concentrations did not interfere with APAP detection. The feasibility of the sensor for APAP detection in tablet and serum samples was successfully evaluated. The qualities of this sensor, including its rapid-response, sensitivity and ease of use, maybe beneficial for potential applications in detecting other drugs

Introducing a novel nanocomposite consisting of nitrogen-doped carbon nano-onions and gold nanoparticles for the electrochemical sensor to measure acetaminophen

In the present study, gold nanoparticles and nitrogen-doped carbon nano-onions (AuNP/NCNO) in a nanocomposite-based sensor were reported for the electrochemical detection of acetaminophen (APAP). The NCNOs from the fullerene family were prepared using a simple and cost-effective method using aminated nanodiamonds (AM-ND) as a substrate. Nitrogen atoms were introduced into CNO cages during the preparation of these nanostructures by annealing AM-NDs under an inert helium atmosphere and reduced pressure. AuNPs were synthesized using a straightforward method. The nanocomposite profoundly enhanced the active surface area of the glassy carbon electrode and amplified the electron transfer rate. Accordingly, electrocatalysis of the APAP was achieved at the modified electrode surface at 0.38 V vs. Ag/AgCl. Under the optimal conditions, the sensor displayed a linear response for APAP detection ranging from 25 nM to 35 μM with a limit of detection (LOD) of 9 nM. Potentially interfering drugs, such as ascorbic acid and dopamine, with 5-fold higher concentrations did not interfere with APAP detection. The feasibility of the sensor for APAP detection in tablet and serum samples was successfully evaluated. The qualities of this sensor, including its rapid-response, sensitivity and ease of use, maybe beneficial for potential applications in detecting other drugs. © 202

A glassy carbon electrode modified with carbon nanoonions for electrochemical determination of fentanyl

Fentanyl is a pain reliever stronger and deadlier than heroin. This lethal drug has killed many people in different countries recently. Due to the importance of the diagnosis of this drug, a fentanyl electrochemical sensor is developed based on a glassy carbon electrode (GCE) modified with the carbon nanoonions (CNOs) in this study. Accordingly, the electrochemical studies indicated the sensor is capable of the voltammetric determination of traces of fentanyl at a working potential of 0.85 (vs. Ag/AgCl). To obtain the great efficiency of the sensor some experimental factors such as time, the potential of accumulation and pH value of the electrolyte were optimized. The results illustrated a reduction and two oxidation peaks for fentanyl in phosphate buffer (PB) with pH = 7.0 under a probable mechanism of electrochemical-chemical-electrochemical (ECE). The differential pulse voltammetry (DPV) currents related to the fentanyl detection were linear with an increase of fentanyl concentrations in a linear range between 1 mu M to 60 mu M with a detection limit (LOD) of 300 nM. Furthermore, the values of the diffusion coefficient (D), transfer coefficient (alpha) and catalytic constant rate (k(cat)) were calculated to be 2.76 x 10(-6) cm(2) s(-1), 0.54 and 1.76 x 10(4) M-1 s(-1), respectively. These satisfactory results may be attributed to utilizing the CNOs in the electrode modification process due to some of its admirable characterizations of this nanostructure including high surface area, excellent electrical conductivity and good electrocatalytic activity. Consequently, these finding points the achieving a simple sensing system to measure of the fentanyl as an important drug from the judicial perspective might be a dream coming true soon

A phenol-formaldehyde polymeric network to generate organic aerogels: Synthesis, physicochemical characteristics and potential applications

In this study, phenol-formaldehyde (PhF) resins, bisphenol A diglycidyl ether and 4-vinylpyridine were used for the preparation of two organic aerogels (AGs). The data showed that the organic AGs exhibited porous and functionalized structures resulting in efficient Cu(ii) and Mn(ii) ion removal from water sources. The AGs showed also fairly good sorption properties towards organic solvents and dyes. Combined complex permittivity and ac electrical conductivity measurements sense structural changes, indicating that AGs can also be promising sensors for the interaction of fluids interpenetrating their porous system. © 2018 The Royal Society of Chemistry

Metal Nitride Cluster Fullerene M 3 N@C 80 (M = Y, Sc) Based Dyads: Synthesis, and Electrochemical, Theoretical and Photophysical Studies

Abstract: The first pyrrolidine and cyclopropane derivatives of the trimetallic nitride templated (TNT) endohedral metallofullerenes I h -Sc 3 N@C 80 and I h -Y 3 N@C 80 connected to an electrondonor unit (i.e., tetrathiafulvalene, phthalocyanine or ferrocene) were successfully prepared by 1,3-dipolar cycloaddition reactions of azomethine ylides and Bingel-Hirsch-type reactions. Electrochemical studies confirmed the formation of th