39 research outputs found
Nitrogen and phosphorus limitation and the management of small productive lakes
- Publication venue
- 'Informa UK Limited'
- Publication date
- 01/08/2020
- Field of study
Many inland waters are enriched with nutrients, causing deleterious effects to their ecology and the benefits they provide for society, but their effective management first requires identification of the nutrient(s) that limit algal production. Concentrations of nutrients and chlorophyll a (Chl-a) were used to assess nutrient limitation seasonally at 17 meres over 2 time periods: historic (2005–2009; 1995–1998 at one site) and contemporary (2014–2018). Different approaches were used to assess nutrient limitation because they reflect different aspects of nutrient availability and their conversion into biomass. In the historic period, 3 meres were phosphorus (P) limited, 3 nitrogen (N) limited, 5 co-limited; the remaining 6 meres were not nutrient limited. For this period, ecological status assessed using phytoplankton Chl-a was only at good or high ecological status (sensu the Water Framework Directive) at 2 sites. The contemporary period was slightly improved, with 4 sites at good status. At the sites that failed to meet good ecological status, the required reduction in P concentration was least in P-limited sites and, conversely, the reduction in N was least in N-limited sites, suggesting that remediation by nutrient reduction would be most efficient if it was targeted using site-specific information. Even in primarily P-limited sites, once input of P has been reduced, further ecological benefit of reducing N at targeted sites should be explored
Redundancy in the ecological assessment of lakes: Are phytoplankton, macrophytes and phytobenthos all necessary?
- Author
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/10/2016
- Field of study
Although the Water Framework Directive specifies that macrophytes and phytobenthos should be used for the ecological assessment of lakes and rivers, practice varies widely throughout the EU. Most countries have separate methods for macrophytes and phytobenthos in rivers; however, the situation is very different for lakes. Here, 16 countries do not have dedicated phytobenthos methods, some include filamentous algae within macrophyte survey methods whilst others use diatoms as proxies for phytobenthos. The most widely-cited justification for not having a dedicated phytobenthos method is redundancy, i.e. that macrophyte and phytoplankton assessments alone are sufficient to detect nutrient impacts. Evidence from those European Union Member States that have dedicated phytobenthos methods supports this for high level overviews of lake condition and classification; however, there are a number of situations where phytobenthos may contribute valuable information for the management of lakes
Nutrient criteria for surface waters under the European Water Framework Directive: current state-of-the-art, challenges and future outlook
- Author
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2019
- Field of study
The aim of European water policy is to achieve good ecological status in all rivers, lakes, coastal and transitional waters by 2027. Currently, more than half of water bodies are in a degraded condition and nutrient enrichment is one of the main culprits. Therefore, there is a pressing need to establish reliable and comparable nutrient criteria that are consistent with good ecological status.
This paper highlights the wide range of nutrient criteria currently in use by Member States of the European Union to support good ecological status and goes on to suggest that inappropriate criteria may be hindering the achievement of good status. Along with a comprehensive overview of nutrient criteria, we provide a critical analysis of the threshold concentrations and approaches by which these are set. We identify four essential issues: (1) Different nutrients (nitrogen and/or phosphorus) are used for different water categories in different countries. (2) The use of different nutrient fractions (total, dissolved inorganic) and statistical summary metrics (e.g., mean, percentiles, seasonal, annual) currently hampers comparability between countries, particularly for rivers, transitional and coastal waters. (3) Wide ranges in nutrient threshold values within shared water body types, in some cases showing more than a 10-fold difference in concentrations. (4) Different approaches used to set threshold nutrient concentrations to define the boundary between “good” and “moderate” ecological status. Expert judgement-based methods resulted in significantly higher (less stringent) good-moderate threshold values compared with data-driven approaches, highlighting the importance of consistent and rigorous approaches to criteria setting.
We suggest that further development of nutrient criteria should be based on relationships between ecological status and nutrient concentrations, taking into account the need for comparability between different water categories, water body types within these categories, and countries
A meta-analysis of water quality and aquatic macrophyte responses in 18 lakes treated with lanthanum modified bentonite (PHOSLOCK®)
- Author
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2016
- Field of study
Lanthanum (La) modified bentonite is being increasingly used as a geo-engineering tool for the control of phosphorus (P) release from lake bed sediments to overlying waters. However, little is known about its effectiveness in controlling P across a wide range of lake conditions or of its potential to promote rapid ecological recovery. We combined data from 18 treated lakes to examine the lake population responses in the 24 months following La-bentonite application (range of La-bentonite loads: 1.4 to 6.7 tonnes ha-1) in concentrations of surface water total phosphorus (TP; data available from 15 lakes), soluble reactive phosphorus (SRP; 14 lakes), and chlorophyll a (15 lakes), and in Secchi disk depths (15 lakes), aquatic macrophyte species numbers (6 lakes) and aquatic macrophyte maximum colonisation depths (4 lakes) across the treated lakes. Data availability varied across the lakes and variables, and in general monitoring was more frequent closer to the application dates. Median annual TP concentrations decreased significantly across the lakes, following the La-bentonite applications (from 0.08 mg L-1 in the 24 months pre-application to 0.03 mg L-1 in the 24 months post-application), particularly in autumn (0.08 mg L-1 to 0.03 mg L-1) and winter (0.08 mg L-1 to 0.02 mg L-1). Significant decreases in SRP concentrations over annual (0.019 mg L-1 to 0.005 mg L-1), summer (0.018 mg L-1 to 0.004 mg L-1), autumn (0.019 mg L-1 to 0.005 mg L-1) and winter (0.033 mg L-1 to 0.005 mg L-1) periods were also reported. P concentrations following La-bentonite application varied across the lakes and were correlated positively with dissolved organic carbon concentrations. Relatively weak, but significant responses were reported for summer chlorophyll a concentrations and Secchi disk depths following La-bentonite applications, the 75th percentile values decreasing from 119 μg L-1 to 74 μg L-1 and increasing from 398 cm to 506 cm, respectively. Aquatic macrophyte species numbers and maximum colonisation depths increased following La-bentonite application from a median of 5.5 species to 7.0 species and a median of 1.8 m to 2.5 m, respectively. The aquatic macrophyte responses varied significantly between lakes. La-bentonite application resulted in a general improvement in water quality leading to an improvement in the aquatic macrophyte community within 24 months. However, because, the responses were highly site-specific, we stress the need for comprehensive pre- and post-application assessments of processes driving ecological structure and function in candidate lakes to inform future use of this and similar products
Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial
- Author
- Abano Nenette
- Abbdul-saheb Mudhar
- Adedoyin Temi
- Adell Victoria
- Adesina Tolu
- Adie Katja
- Adil-Smith Jennifer
- Ahmad Nasar
- Ahmed Ashraf
- Ahmed Iman
- Al-Mayhani Talal
- Al-Shahi Salman Rustam
- Al-Shahi Salman Rustam
- Alam Mohammad Irfan
- Albazzaz Mo
- Ali Ali
- Alipio Francis
- Allen Christopher
- Allison Joanna
- Amey Isobel
- Amis Elaine
- Amlani Sageet
- Amoils Shannon
- Amor Kelly
- Anderson Rosemary
- Andole Sreeman
- Anjum Talat
- Ankolekar Sandeep
- Annamalai Arunkumar
- Anthony Alpha
- Anversha Ajmal
- Anwar Ijaz
- Anwar Sajjad
- Appleton Jason
- Argandona Lucia
- Armitage Jane
- Ashton Amy
- Atkinson Natalie
- Auld Grace
- Avis Joanne
- Aweid Basaam
- Ayres Georgina
- Azhar Khalid
- Bagnall Caroline
- Baig Farrukh
- Baigent Colin
- Bailey Duncan
- Baird Yolanda
- Bakawala Rehana
- Baker John
- Baker Pauline
- Balazikova Olga
- Balian Linda
- Baliga Vidya
- Balitska Olesia
- Ball Julie
- Ball Margaret
- Ballantine Robert
- Bamford John
- Banaras Azra
- Barber Mark
- Barbon Emma
- Barker James
- Barr Charlotte
- Barrie Elizabeth
- Barron Luke
- Barry Adrian
- Bateman Gavin
- Bates Michelle
- Bathula Rajaram
- Battersby-Wood Emma
- Bayliss Pauline
- Beadle Hannah
- Bearne Helen
- Beaty Teresa
- Beaves Emily
- Bell Angela
- Bell Jo
- Bell Murdina
- Bellfield Ruth
- Beranova Eva
- Bergin Adrian
- Bhakri Harbens
- Bhalla Ajay
- Bharaj Kiranjit
- Bhargava Maneesh
- Bhaskaran Biju
- Bhatnagar Priya
- Bhatnagar Priya
- Birchall Kathryn
- Birns Jonathan
- Black Toby
- Blades Alex
- Blair Caroline
- Blair Caroline
- Blair Gordon
- Blane Sujata
- Blank Catrin
- Blight Adrian
- Board Joanne
- Board Sarah
- Bokhari Maria
- Bond Kirsty
- Bowring Angela
- Boxall Cherish
- Breeds Joanna
- Brew Helen
- Brezitski Maria
- Bridger Hayley
- Brodie Fiona
- Brotherton Lucy
- Broughton David
- Brown Claire
- Brown Ellen
- Brown Pauline
- Brown Sarah
- Bruce David
- Buchanan David
- Buck Amanda
- Buckle Steve
- Buckle Steve
- Buckley Clare
- Bunea George
- Burger Ilse
- Burgess Laura
- Burgess Seona
- Burssens Evelyne
- Butler Adrian
- Butler Donna
- Butler Rebecca
- Butterworth-Cowin Nicola
- Button Denise
- Buxton Jean
- Byrne Anthony
- Cageao Julie
- Caine Sarah
- Campbell Robert
- Carpenter Michael
- Carpio Racquel
- Carrie Johanna
- Cassidy Tim
- Causley Chelsea
- Chadbourn Indra
- Chadha Dinesh
- Chamberlain Angela
- Chan kelly
- Chandrakumar Aberami
- Chapman Kath
- Chapman Nicola
- Charles Bethan
- Chatterjee Kausic
- Chaudhry Afnan
- Chauhan Meena
- Chenna Srikanth
- Cherian Suja
- Cheripelli Bharath Kumar
- Chopra Neha
- Choulerton James
- Choy Lillian
- Clarke Brian
- Clarke Caroline
- Clarke Judith
- Clarke Natasha
- Clarke Rebecca
- Clarke Samantha
- Clarkson Emma
- Clay Caroline
- Clayton Susan
- Clayton-Evans Lisa
- Cluckie Gillian
- Cochrane Helen
- Codd Laura
- Cohen David
- Collins Kayleigh
- Connor Lynda
- Constantin Carmen
- Cook Angela
- Cooper Martin
- Copeland Claire
- Cosier Tracey
- Courtauld Gillian
- Couser Mandy
- Coward Lucy
- Cowie Linda
- Cox Chantel
- Cox Chloe
- Cox Penelope
- Crabtree Karen
- Crawford Pam
- Crawford Susan
- Creeden Robyn
- Crisp Sarah
- Cronin Julie
- Crook Luci
- Crosbie Caroline
- Crouch Nichola
- Crown Rachel
- Crowther Hannah
- Cuddy Sarah
- Cuenoud Larissa
- Cullen Claire
- Culmsee Charlotte
- Cunningham James
- Cunningham Mishell
- Cvoro Vera
- Dacey Lynne
- Dakin Katy
- Dallol Bander
- Dangri Puneet
- Datta Prabal
- Davey Richard
- David Anette
- David Owen
- Davies Caroline
- Davies Ruth
- Davies Silvie
- Davis Fiona
- Davis Michelle
- Day Nicola
- Dayal Nilofer
- De Berker Henry
- Deary Ann
- Denic Hayley
- Dennis Martin
- Dennis Martin S
- Denniss Carol
- Devine Joseph
- Devitt Nicola
- Dewar Richard
- Dhakal Mahesh
- Dhar Saikat
- Dickinson Christina
- Dickson Christine
- Dima Sofia
- Dinsmore Lynn
- Dixon Lynn
- Dobson Tracey
- Dodd Angela
- Dodd Emily
- Doherty Mandy
- Doherty Mandy
- Donaldson Denise
- Donnelly Richard
- Doubal Fergus
- Dow Lindsey
- Downham Susan
- Doyle Clare
- Doyle Donna
- Drever Jonathan
- du Plessis Johann C
- du Plessis Johannes
- Dube Judith
- Duberley Stephen
- Dunn Linda
- Dunne Karen
- Durairaj Ramesh
- Durman Helen
- Dutta Dipankar
- Dynan Kevin
- Edwards Mandy
- Egerton Shuna
- Eglinton Charlotte
- Eglinton Charlotte
- El Tawil Salwa
- Elfandi Khaled
- Elliot Jennifer
- Elliott Emma
- Ellis Sam
- Emberson Jonathan
- Emsley Hedley
- England Timothy
- Epstein Daniel
- Erande Renuka
- Erumere Esther
- Esisi Bernard
- Esisi Bernard
- Esson Derek
- Esson Derek
- Evans Rachel
- Evans Sue
- Eveson David
- Ewing Jordan
- Fathima Razik
- Fawcett Michelle
- Feerick Shez
- Fennelly Ruth
- Ferdinand Phillip
- Findlay Paul
- Finlay Sarah
- Finney Kay
- Fitzell Pauline
- Fitzsimmons Paul
- Fletcher Glyn
- Fletcher Jo
- Fong Rosanna
- Foot Jayne
- Foote Leanne
- Ford Gary
- Foster Eliza
- Fotherby Ken
- Fox Charlotte
- Francia Nina
- Francis Jobbin
- Fraser Ruth
- Fraser Ruth
- Fuller Tracy
- Fulton Ailsa
- Furnace Jacqueline
- Gadapa Naveen
- Gainard Glyn
- Gainsborough Nicola
- Gallagher Jill
- Gallagher Louise
- Gallifent Rachel
- Gamble Ed
- Garcia Tatiana
- Gardener Léjeune
- Garfield-Smith Joanne
- Garside Mark
- Gartrell Imogen
- Gascoyne Rachel
- Gattringer Thomas
- Gautam Nikki
- Gaylard Jane
- Gbadamoshi Lukuman
- Geraghty Olivia
- Ghaly George
- Ghatala Rita
- Ghosh Sandip
- Giallombardo Elio
- Gilham Ellie
- Gilmour Danielle
- Gilzeane Nicola
- Glass Jon
- Gleave Laura
- Glover Rachel
- Godfrey Margi
- Goff Anita
- Goorah Neetish
- Gott Valerie
- Gow Heather
- Graham Carol
- Graham Ruth
- Gray Jane
- Green Carole
- Greenwood Richard
- Gregory Bindu
- Greig Jill
- Grimwood Gemma
- Grocott Jeanette
- Grue Rebecca
- Gulliver Diane
- Guo Fenglin
- Gupwell Karin
- Guthrie Lucy Belle
- Guy Helen
- Guyler Paul
- Hague Adam
- Haider Syed
- Hairsine Brigid
- Hakim Eluzai
- Hall Andrea
- Halse Omid
- Handley Dominic
- Hann Gail
- Hannon Niamh
- Hansen Christian
- Haque Mohammad
- Hardwick Anne
- Harkness Kirsty
- Harrington Frances
- Harrington-Davies Yasmin
- Harrison Louise
- Harrison Melanie
- Harrison Thomas
- Harston George
- Harvey Kirsten
- Harvey Miriam
- Hassan Ahamad
- Hassan Hardi
- Havard Diane
- Hayes Anne
- Hayhoe Helen
- Hayman Rachel
- Hays Carole
- Hazel Beth
- Hedstrom Amanda
- Hedstrom Amanda
- Hemsley Anthony
- Henry Margo
- Herman Jane
- Hervey Simon
- Hewitt Jonathan
- Hiden Joanne
- Hogan Caroline
- Hogg Valerie
- Holden Melinda
- Holmes Clare
- Homan Jane
- Hooley Michaela
- Horan Kathleen
- Horton Sarah
- Hostettler Isabel
- Hove Dionne
- Howaniec Laura
- Howard Gabriella
- Howard Joanne
- Howard Peter
- Howcroft Deborah
- Howe Jo
- Huang Xuya
- Huggett Isabel
- Hughes Chloe
- Hughes Claire
- Hughes Tom
- Humphreys Louise
- Humphries Fiona
- Hunt Benjamin
- Hunt Nicholas
- Hunter Annemarie
- Hunter Neil
- Hurford Frances
- Hurley Jennifer
- Hussain Malik
- Hutchison Aidan
- Hyams Benjamin
- Hyatt Lisa
- Imam Javed
- Ingham Andrea
- Ingram Tanya
- Innes Karen
- Iqbal Arshi
- Iqbal Mohammad Shazad
- Irvine Janice
- Ispoglou Sissy
- Ivatts Simone
- Jackson Benjamin
- Jackson Linda
- Jagger Jenny
- Jagpal Baljit
- James Ali
- James Claire
- James Martin
- Jarapa Rowilson
- Jarrett David
- Jeffs Carol
- Jelley Benjamin
- Jenkins Colin
- Jennings-Preece Karla
- Jeyaraj Naomi
- Jha Ratneshwari
- Jinks Emma
- Johnes Mary
- Johnson Sharon
- Jones Ifan
- Jones Ifan
- Jones Kirsty
- Jones Rachael
- Jones Stephanie
- Jones Terry
- Jones Val
- Jordan Carla
- Jose Deepa
- Jose Josin
- Joshi Yogish
- Joshi Yogish
- Joyson Anu
- Jupp Becky
- Justin Frances
- Kakar Puneet
- Kalathil Latheef
- Kalladka Dheeraj
- Kamara Christine
- Kambafwile Mary
- Kane Ingrid
- Kar Arindam
- Keegan Breffni
- Keeling Elizabeth
- Keenan Samantha
- Kelavkar Shyam
- Kelly Christine
- Kelly Debs
- Kelly Jim
- Kelly Siobhan
- Keltos Marketa
- Kennedy James
- Kennedy Kate
- Kenton Antony
- Kerin Lourda
- Kerr Enda
- Kerr Gillian
- Keshvara Rekha
- Khan Mohammad
- Khan Shagufta
- Khan Usman
- Khan Uzma
- Kibutu Faith
- King Sam
- Kingwell Hayley
- Kini Manohar
- Klaasen Katrina
- Knops Kerstin
- Krishnamoorthy Shrivakumar
- Krishnamurthy Ramesh
- Krishnamurthy Vinodh
- Krishnan Kailash
- Krishnan Manju
- Krommyda Magdalini
- Kullane Sagal
- Kumar Balakrishna
- Kumar Pradeep
- Kunhunny Swapna
- Lam Man Yee
- Lambert Caroline
- Landers Geraldine
- Langhorne Peter
- Lasserson Daniel
- Latter Laura
- Law Zhe
- Lawrence Tara
- Lawson Heidi
- Leason Sandra
- Lee Stephanie
- Leggett Jacqui
- Lenti Giulia
- Lerpiniere Christine
- Lerpiniere Christine
- Licenik Radim
- Lindert Ralf
- Little Victoria
- Littleton Edward
- Ljubez Anja
- Loganathan Thayalini
- Longland Barbara
- Lopez Paula
- Lovelock Caroline
- Lowe Gordon
- Lucas Linda
- Lucas Suzanne
- Luder Robert
- Lyjko Sue
- Maanoosi Mehran
- Maatouk Ahmad
- Macaden Ashish
- MacInnes Brian
- MacLennan Beverly
- Macleod Malcolm
- MacLeod Mary
- MacLiver Linda
- MacRaild Allan
- Maddula Mohana
- Madigan Barbara
- Maguire Holly
- Maguire Stuart
- Maiden Susan
- Majis Arshad
- Majmudar Nikhil
- Makawa Linetty
- Mangion David
- Manning Lisa
- Manoj Aravind
- Mardania Rina
- Marigold James Richard
- Markova Skarlet
- Marks Katherine
- Marsden Tracy
- Marshall Sally
- Martin Irene
- Mashate Sheila
- Mason Cathy
- Mate Abhijit
- Mathieson Philip
- Matias Oliver
- Matthews Christopher
- Maund Bev
- McAlpine Christine
- McArdle Damian
- Mcauley Sean
- McCann Stephanie
- McCarron Mark
- McClelland Beverley
- McCormick Katrina
- McCormick Katrina
- McDonald Shanni
- McDonald Susan
- Mcgee Joanne
- McGhee Caroline
- McGill Connor
- McGrath Aileen
- McIlmoyle James
- McKee Jacqueline
- McLoughlin Alison
- McVerry Ferghal
- Mead Denise
- Mead Gillian
- Meir Julie
- Menon Nisha
- Mercer Lily
- Metcalf Kneale
- Miller Keniesha
- Miller Richard
- Milligan Josette
- Minks David
- Minks David P.
- Miriam Skelton
- Mistri Amit
- Mitchell Jennifer
- Mitra Dipayan
- Mitra Dipayan
- Mohammed Niaz
- Mohd Nor Azlisham
- Mokoena Betty
- Moores Andrew
- Moqsith Mohammed
- Morell Jordi
- Moreton Fiona
- Morgan Debbie
- Moroney Helen
- Morse Bethan
- Moseley Sally
- Motherwell Nichola
- Moynihan Barry
- Mpelembue Mushiya
- Mudd Paul
- Muddegowda Girish
- Muir Keith
- Mukherjee Indranil
- Murali Elodie
- Murphy Peter
- Murray Gordon D
- Musarrat Kashif
- Myint Min
- Naeem Muhammad
- Naing Zin
- Nair Anand
- Nallasivan Arumugam
- Nasar Mohammad
- Nasim Ashraf
- Naylor Charde
- Needle Ann
- Nelson Sandra
- Newby David E
- Newton Sophie
- Ng Kheng Xiong
- Ngo David
- Nguyen Vinh
- Ngwako Mmua
- Ni Hlaing
- Nicholas Paul
- Nicolson Anne
- Niranchanan Rangah
- Nisar Nabeela
- Njoku Kelechi
- Nott Claire
- Nott Claire
- Nozedar Tarn
- Nyabadza Sheila
- O'Brien Eoin
- O'Brien Richard
- O'Brien Richard
- O'Connell Susan
- O'Loughlin Victoria
- O'Reilly Joanna
- O'Toole Sarah
- OConnell Janice
- Oji Nnebuife
- Orath Prabakaran Rajalakshmi
- Orefo Chukwuka
- Orugun Enoch
- Osborn Mairead
- Osborne Emily
- Oshodi Anne
- Osman Ahmed
- Ovington Catherine
- Owings Paula
- Owoyele Emmanuelle
- Owusu-Agyei Peter
- Pai Yogish
- Palmer Jeb
- Papavasileiou Vasileios
- Parakramawansha Ruwan
- Parker Richard
- Parry Anthea
- Parry-Jones Adrian
- Pasco Kath
- Patel Bhavini
- Patel Champa
- Patel Farzana
- Patel Krishna
- Patterson Chris
- Paulton Ruth
- Pawley Corinne
- Peixoto Cassilda
- Penge Justin
- Perez Jane
- Perfitt Rebekah
- Perkins Charlotte
- Perry David
- Perry Jack
- Persad Nicola
- Peters Jenny
- Pettitt Kerry
- Phiri Duke
- Pitt-Ford Alexandra
- Pitt-Kerby Tressy
- Plewa Catherine
- Poku Philip
- Ponnambath Suheil
- Poultney Una
- Pound Susan
- Power Michael
- Pressly Vanessa
- Price Fiona
- Proeschel Harald
- Punekar Shuja
- Punter Martin
- Pusalkar Aparna
- Putterill Janet
- Quinn Leanne
- Quinn Outi
- Qureshi Sammie
- Ragab Suzanne
- Raghunathan Senthil
- Rahman Bithi
- Rai Baljinder
- Raj Sonia
- Rajapakse Anoja
- Rajkumar Chakravarthi
- Ramachandran Sankaranarayana
- Ramadan Hawraman
- Ramshaw Alex
- Rana Pratap
- Randall Marc
- Rashed Khalid
- Rashmi Sindhu
- Ravenhill Garth
- Rayessa Rayessa
- Reckless Ian
- Reddan Julie
- Reddan Julie
- Redgrave Jessica
- Redjep Ozlem
- Remegoso Alda
- Richard Bella
- Richards Emma
- Rinkel Gabriel
- Roberts Josh
- Robinson Matthew
- Robinson Naomi
- Rodgers Alicia
- Rodrigues Mark A
- Rodriguez Aryelly
- Roffe Christine
- Roffe Jack
- Roganova Tatjana
- Rogers Emily
- Rogers Gill
- Rojas Javier
- Ross Sarah
- Roughan Caroline
- Rudd Tony
- Rudenko Hannah
- Saada Janak
- Saastamoinen Kari
- Sajid Mahmud
- Sakka Eleni
- Salehin Maqsud
- Salek-Haddadi Afraim
- Salih Isam
- Sally Moore
- Sandercock Peter A G
- Sangombe Mirriam
- Sangster Graeme
- Sanyal Ranjan
- Sarah Procter
- Sarah Procter
- Sattar Naweed
- Sattar Saira
- Saulat Afaq
- Saulat Afaq
- Schofield Christine
- Schulz Ursula
- Schumacher Natasha
- Schwarz Stefan
- Seagrave Samantha
- Sekaran Lakshmanan
- Sesay Juliana
- Sethuraman Sakthivel
- Shackcloth Daniela
- Shah Alex
- Shah Sweni
- Shahmehri Shahrzad
- Sharma Nikhil
- Sharpe Simon
- Shaw Kelly Marie
- Shaw Louise
- Sheikh Saima
- Shekhar Raj
- Shelton Faye
- Shinh Naval
- Shread Ian
- Shukla Avani
- Siddegowda Prasad
- Siddiq Muhammad
- Siddiqui Amber
- Siddiqui Anwer
- Sigsworth Andrew
- Simon Rohan
- Sims Don
- Singh Arun
- Sinha Devesh
- Skinner Helen
- Slade Peter
- Smart Amanda
- Smith Andrew
- Smith Fiona
- Smith Gemma Marie
- Smith Simon
- Smith Wilma
- Smyth Nigel
- Spencer Jayne
- Sprigg Nikola
- Sprigg Nikola
- Srinivasan Meena
- Stafford Samantha
- Stafford Samantha
- Stanners Andrew
- Steele Amy
- Stephen Jacqueline
- Stephens Claire
- Stevens Angela
- Stevens Stephanie
- Stevenson Sarah
- Stewart Kelvin
- Stocks Kathy
- Stone Andrew
- Storton Sharon
- Strain David
- Subramonian Santhosh
- Sudlow Cathie
- Sudlow Cathie L M
- Sukdeo Varthi
- Sullivan Frank
- Sultan Sulaiman
- Suttling Anne
- Sutton Claire
- Sutton Patrick
- Sutton Victoria
- Sword Jane
- Sykes Lucy
- Symonds Stuart
- Szabo Susan
- Tallantyre Emma
- Tanate Alfonso
- Tandy Jane
- Tate Margaret
- Tauro Suzanne
- Tayler Michelle
- Taylor Pat
- Taylor Vicky
- Teal Rachel
- Temple Natalie
- Thant Hlaing
- Thavanesan Kamy
- Thomas Isobel
- Thomas Kelly
- Thomas Philip
- Thomas Sarah
- Thompson Philip
- Thompson Susan
- Thompson Teresa
- Thompson-Jones Helen
- Thomson Audrey
- Thornthwaite Sarah
- Thorpe Kevin
- Tilley Victoria
- Tiwari Divya
- Tomlin Dawn
- Tomlinson Benjamin
- Treadwell Shelley
- Tribbeck Michele
- Trippier Sarah
- Triscott Claire
- Triscott Claire
- Tryambake Dinesh
- Tucker Laura
- Tucker Susan
- Turfrey Jennifer
- Tysoe Sharon
- Ullah Khalil
- Valentine Stacey
- van Someren Chloe
- Varquez Resti
- Vasileiadis Evangelos
- Vassallo Joseph
- Venter Marius
- Veraque Emelda
- Verrion Anna
- Vettimootal Johnson Venetia
- Vickers Carinna
- Walford Jamie
- Walker Allan
- Walker Marion
- Walker Pauli
- Walker Susannah
- Wallace Aine
- Wallace Rebecca
- Wallace Rebecca
- Walstow Deborah
- Walter Deborah
- Walters Ashleigh
- Wani Mushtaq
- Ward Deborah
- Wardlaw Joanna M
- Watchurst Caroline
- Waterfield Kelly
- Waterfield Kelly
- Watson Fran
- Waugh Dean
- Webb Tom
- Webber Adam
- Webster Timothy
- Weinling Marie
- Weir Nic
- Weir Pauline
- Welch Angela
- Werring David
- Werring David J
- Whitcher Alison
- White James
- White Julie
- White Philip M
- White Susan
- Whiteley William
- Whiteley William N
- Whiteman Jessica
- Whiteman Jessica
- Whiting Robert
- Whittamore Katherine
- Wiggam Ivan
- Wilding Peter
- Wilkes Gwendoline
- Wilkinson Mark
- Willberry Angela
- Williams Carol
- Williams Rebecca
- Williams-Yesson Barbara
- Willmot Mark
- Wilson David
- Wilson Duncan
- Wilson Jenny
- Wilson Lisa
- Wilson Sarah
- Wiltshire Alison
- Wood Diane
- Wood Edith
- Wood Lisa
- Woodward Stephen
- Wright Fiona
- Wroath Belinda
- Wynter Inez
- Yadava Rajendra
- Yip Brigitte
- Young Andrew
- Zachariah George
- Zahoor Tajammal
- Zoe Mellor
- Publication venue
- 'Elsevier BV'
- Publication date
- 22/05/2019
- Field of study
Background
Findings from the RESTART trial suggest that starting antiplatelet therapy might reduce the risk of recurrent symptomatic intracerebral haemorrhage compared with avoiding antiplatelet therapy. Brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases (such as cerebral microbleeds) are associated with greater risks of recurrent intracerebral haemorrhage. We did subgroup analyses of the RESTART trial to explore whether these brain imaging features modify the effects of antiplatelet therapy
Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial
- Author
- Abano Nenette
- Abbdul-saheb Mudhar
- Adedoyin Temi
- Adell Victoria
- Adesina Tolu
- Adie Katja
- Adil-Smith Jennifer
- Ahmad Nasar
- Ahmed Ashraf
- Ahmed Iman
- Al-Mayhani Talal
- Al-Shahi Salman Rustam
- Alam Mohammad Irfan
- Albazzaz Mo
- Ali Ali
- Alipio Francis
- Allen Christopher
- Allison Joanna
- Amey Isobel
- Amis Elaine
- Amlani Sageet
- Amoils Shannon
- Amor Kelly
- Anderson Rosemary
- Andole Sreeman
- Anjum Talat
- Ankolekar Sandeep
- Annamalai Arunkumar
- Anthony Alpha
- Anversha Ajmal
- Anwar Ijaz
- Anwar Sajjad
- Appleton Jason
- Argandona Lucia
- Armitage Jane
- Ashton Amy
- Atkinson Natalie
- Auld Grace
- Avis Joanne
- Aweid Basaam
- Ayres Georgina
- Azhar Khalid
- Bagnall Caroline
- Baig Farrukh
- Baigent Colin
- Bailey Duncan
- Baird Yolanda
- Bakawala Rehana
- Baker John
- Baker Pauline
- Balazikova Olga
- Balian Linda
- Baliga Vidya
- Balitska Olesia
- Ball Julie
- Ball Margaret
- Ballantine Robert
- Bamford John
- Banaras Azra
- Barber Mark
- Barbon Emma
- Barker James
- Barr Charlotte
- Barrie Elizabeth
- Barron Luke
- Barry Adrian
- Bateman Gavin
- Bates Michelle
- Bathula Rajaram
- Battersby-Wood Emma
- Bayliss Pauline
- Beadle Hannah
- Bearne Helen
- Beaty Teresa
- Beaves Emily
- Bell Angela
- Bell Jo
- Bell Murdina
- Bellfield Ruth
- Beranova Eva
- Bergin Adrian
- Bhakri Harbens
- Bhalla Ajay
- Bharaj Kiranjit
- Bhargava Maneesh
- Bhaskaran Biju
- Bhatnagar Priya
- Birchall Kathryn
- Birns Jonathan
- Black Toby
- Blades Alex
- Blair Caroline
- Blair Caroline
- Blair Gordon
- Blane Sujata
- Blank Catrin
- Blight Adrian
- Board Joanne
- Board Sarah
- Bokhari Maria
- Bond Kirsty
- Bowring Angela
- Boxall Cherish
- Breeds Joanna
- Brew Helen
- Brezitski Maria
- Bridger Hayley
- Brodie Fiona
- Brotherton Lucy
- Broughton David
- Brown Claire
- Brown Ellen
- Brown Pauline
- Brown Sarah
- Bruce David
- Buchanan David
- Buck Amanda
- Buckle Steve
- Buckle Steve
- Buckley Clare
- Bunea George
- Burger Ilse
- Burgess Laura
- Burgess Seona
- Burssens Evelyne
- Butler Adrian
- Butler Donna
- Butler Rebecca
- Butterworth-Cowin Nicola
- Button Denise
- Buxton Jean
- Byrne Anthony
- Cageao Julie
- Caine Sarah
- Campbell Robert
- Carpenter Michael
- Carpio Racquel
- Carrie Johanna
- Cassidy Tim
- Causley Chelsea
- Chadbourn Indra
- Chadha Dinesh
- Chamberlain Angela
- Chan Kelly
- Chandrakumar Aberami
- Chapman Kath
- Chapman Nicola
- Charles Bethan
- Chatterjee Kausic
- Chaudhry Afnan
- Chauhan Meena
- Chenna Srikanth
- Cherian Suja
- Cheripelli Bharath Kumar
- Chopra Neha
- Choulerton James
- Choy Lillian
- Clarke Brian
- Clarke Caroline
- Clarke Judith
- Clarke Natasha
- Clarke Rebecca
- Clarke Samantha
- Clarkson Emma
- Clay Caroline
- Clayton Susan
- Clayton-Evans Lisa
- Cluckie Gillian
- Cochrane Helen
- Codd Laura
- Cohen David
- Collins Kayleigh
- Connor Lynda
- Constantin Carmen
- Cook Angela
- Cooper Martin
- Copeland Claire
- Cosier Tracey
- Courtauld Gillian
- Couser Mandy
- Coward Lucy
- Cowie Linda
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- Cox Chloe
- Cox Penelope
- Crabtree Karen
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- Crawford Susan
- Creeden Robyn
- Crisp Sarah
- Cronin Julie
- Crook Luci
- Crosbie Caroline
- Crouch Nichola
- Crown Rachel
- Crowther Hannah
- Cuddy Sarah
- Cuenoud Larissa
- Cullen Claire
- Culmsee Charlotte
- Cunningham James
- Cunningham Mishell
- Cvoro Vera
- Dacey Lynne
- Dakin Katy
- Dallol Bander
- Dangri Puneet
- Datta Prabal
- Davey Richard
- David Anette
- David Owen
- Davies Caroline
- Davies Ruth
- Davies Silvie
- Davis Fiona
- Davis Michelle
- Day Nicola
- Dayal Nilofer
- De Berker Henry
- Deary Ann
- Denic Hayley
- Dennis MS
- Denniss Carol
- Devine Joseph
- Devitt Nicola
- Dewar Richard
- Dhakal Mahesh
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- Doherty Mandy
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- Doyle Donna
- Drever Jonathan
- du Plessis Johannes
- Dube Judith
- Duberley Stephen
- Dunn Linda
- Dunne Karen
- Durairaj Ramesh
- Durman Helen
- Dutta Dipankar
- Dynan Kevin
- Edwards Mandy
- Egerton Shuna
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- Eglinton Charlotte
- El Tawil Salwa
- Elfandi Khaled
- Elliot Jennifer
- Elliott Emma
- Ellis Sam
- Emberson Jonathan
- Emsley Hedley
- England Timothy
- Epstein Daniel
- Erande Renuka
- Erumere Esther
- Esisi Bernard
- Esisi Bernard
- Esson Derek
- Esson Derek
- Evans Rachel
- Evans Sue
- Eveson David
- Ewing Jordan
- Fathima Razik
- Fawcett Michelle
- Feerick Shez
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- Finlay Sarah
- Finney Kay
- Fitzell Pauline
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- Garside Mark
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- Haque Mohammad
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- Harkness Kirsty
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- Huang Xuya
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- Imam Javed
- Ingham Andrea
- Ingram Tanya
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- Iqbal Mohammad Shahzad
- Irvine Janice
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- Ivatts Simone
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- Jackson Linda
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- Jagpal Baljit
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- Jarrett David
- Jeffs Carol
- Jelley Benjamin
- Jenkins Colin
- Jennings-Preece Karla
- Jeyaraj Naomi
- Jha Ratneshwari
- Jinks Emma
- Johnes Mary
- Johnson Sharon
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- Jose Josin
- Joshi Yogish
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- Kalathil Latheef
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- Kamara Christine
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- Kar Arindam
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- Kingwell Hayley
- Kini Manohar
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- Knops Kerstin
- Krishnamoorthy Shrivakumar
- Krishnamurthy Ramesh
- Krishnamurthy Vinodh
- Krishnan Kailash
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- Kullane Sagal
- Kumar Balakrishna
- Kumar Pradeep
- Kunhunny Swapna
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- Lambert Caroline
- Landers Geraldine
- Langhorne Peter
- Lasserson Daniel
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- Leason Sandra
- Lee Stephanie
- Leggett Jacqui
- Lenti Giulia
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- Lindert Ralf
- Little Victoria
- Littleton Edward
- Ljubez Anja
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- Longland Barbara
- Lopez Paula
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- Lowe Gordon
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- Lucas Suzanne
- Luder Robert
- Lyjko Sue
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- MacLennan Beverly
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- Macleod MR
- MacLiver Linda
- MacRaild Allan
- Maddula Mohana
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- Majmudar Nikhil
- Makawa Linetty
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- Tiwari Divya
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- Tomlinson Benjamin
- Treadwell Shelley
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- Trippier Sarah
- Triscott Claire
- Triscott Claire
- Tryambake Dinesh
- Tucker Laura
- Tucker Susan
- Turfrey Jennifer
- Tysoe Sharon
- Ullah Khalil
- Valentine Stacey
- van Someren Chloe
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- Vasileiadis Evangelos
- Vassallo Joseph
- Venter Marius
- Veraque Emelda
- Verrion Anna
- Vettimootal Johnson Venetia
- Vickers Carinna
- Walford Jamie
- Walker Allan
- Walker Marion
- Walker Pauli
- Walker Susannah
- Wallace Aine
- Wallace Rebecca
- Wallace Rebecca
- Walstow Deborah
- Walter Deborah
- Walters Ashleigh
- Wani Mushtaq
- Ward Deborah
- Wardlaw JM
- Watchurst Caroline
- Waterfield Kelly
- Waterfield Kelly
- Watson Fran
- Waugh Dean
- Webb Tom
- Webber Adam
- Webster Timothy
- Weinling Marie
- Weir Nic
- Weir Pauline
- Welch Angela
- Werring DJ
- Whitcher Alison
- White James
- White Julie
- White PM
- White Susan
- Whiteley WN
- Whiteman Jessica
- Whiteman Jessica
- Whiting Robert
- Whittamore Katherine
- Wiggam Ivan
- Wilding Peter
- Wilkes Gwendoline
- Wilkinson Mark
- Willberry Angela
- Williams Carol
- Williams Rebecca
- Williams-Yesson Barbara
- Willmot Mark
- Wilson David
- Wilson Duncan
- Wilson Jenny
- Wilson Lisa
- Wilson Sarah
- Wiltshire Alison
- Wood Diane
- Wood Edith
- Wood Lisa
- Woodward Stephen
- Wright Fiona
- Wroath Belinda
- Wynter Inez
- Yadava Rajendra
- Yip Brigitte
- Young Andrew
- Zachariah George
- Zahoor Tajammal
- Zoe Mellor
- Publication venue
- 'Elsevier BV'
- Publication date
- 29/06/2019
- Field of study
Background:
Antiplatelet therapy reduces the risk of major vascular events for people with occlusive vascular disease, although it might increase the risk of intracranial haemorrhage. Patients surviving the commonest subtype of intracranial haemorrhage, intracerebral haemorrhage, are at risk of both haemorrhagic and occlusive vascular events, but whether antiplatelet therapy can be used safely is unclear. We aimed to estimate the relative and absolute effects of antiplatelet therapy on recurrent intracerebral haemorrhage and whether this risk might exceed any reduction of occlusive vascular events.
Methods:
The REstart or STop Antithrombotics Randomised Trial (RESTART) was a prospective, randomised, open-label, blinded endpoint, parallel-group trial at 122 hospitals in the UK. We recruited adults (≥18 years) who were taking antithrombotic (antiplatelet or anticoagulant) therapy for the prevention of occlusive vascular disease when they developed intracerebral haemorrhage, discontinued antithrombotic therapy, and survived for 24 h. Computerised randomisation incorporating minimisation allocated participants (1:1) to start or avoid antiplatelet therapy. We followed participants for the primary outcome (recurrent symptomatic intracerebral haemorrhage) for up to 5 years. We analysed data from all randomised participants using Cox proportional hazards regression, adjusted for minimisation covariates. This trial is registered with ISRCTN (number ISRCTN71907627).
Findings:
Between May 22, 2013, and May 31, 2018, 537 participants were recruited a median of 76 days (IQR 29–146) after intracerebral haemorrhage onset: 268 were assigned to start and 269 (one withdrew) to avoid antiplatelet therapy. Participants were followed for a median of 2·0 years (IQR [1·0– 3·0]; completeness 99·3%). 12 (4%) of 268 participants allocated to antiplatelet therapy had recurrence of intracerebral haemorrhage compared with 23 (9%) of 268 participants allocated to avoid antiplatelet therapy (adjusted hazard ratio 0·51 [95% CI 0·25–1·03]; p=0·060). 18 (7%) participants allocated to antiplatelet therapy experienced major haemorrhagic events compared with 25 (9%) participants allocated to avoid antiplatelet therapy (0·71 [0·39–1·30]; p=0·27), and 39 [15%] participants allocated to antiplatelet therapy had major occlusive vascular events compared with 38 [14%] allocated to avoid antiplatelet therapy (1·02 [0·65–1·60]; p=0·92).
Interpretation:
These results exclude all but a very modest increase in the risk of recurrent intracerebral haemorrhage with antiplatelet therapy for patients on antithrombotic therapy for the prevention of occlusive vascular disease when they developed intracerebral haemorrhage. The risk of recurrent intracerebral haemorrhage is probably too small to exceed the established benefits of antiplatelet therapy for secondary prevention
Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial
- Author
- Abano Nenette
- Abbdul-saheb Mudhar
- Adedoyin Temi
- Adell Victoria
- Adesina Tolu
- Adie Katja
- Adil-Smith Jennifer
- Ahmad Nasar
- Ahmed Ashraf
- Ahmed Iman
- Al-Mayhani Talal
- Al-Shahi Salman Rustam
- Alam Mohammad Irfan
- Albazzaz Mo
- Ali Ali
- Alipio Francis
- Allen Christopher
- Allison Joanna
- Amey Isobel
- Amis Elaine
- Amlani Sageet
- Amoils Shannon
- Amor Kelly
- Anderson Rosemary
- Andole Sreeman
- Anjum Talat
- Ankolekar Sandeep
- Annamalai Arunkumar
- Anthony Alpha
- Anversha Ajmal
- Anwar Ijaz
- Anwar Sajjad
- Appleton Jason
- Argandona Lucia
- Armitage Jane
- Ashton Amy
- Atkinson Natalie
- Auld Grace
- Avis Joanne
- Aweid Basaam
- Ayres Georgina
- Azhar Khalid
- Bagnall Caroline
- Baig Farrukh
- Baigent Colin
- Bailey Duncan
- Baird Yolanda
- Bakawala Rehana
- Baker John
- Baker Pauline
- Balazikova Olga
- Balian Linda
- Baliga Vidya
- Balitska Olesia
- Ball Julie
- Ball Margaret
- Ballantine Robert
- Bamford John
- Banaras Azra
- Barber Mark
- Barbon Emma
- Barker James
- Barr Charlotte
- Barrie Elizabeth
- Barron Luke
- Barry Adrian
- Bateman Gavin
- Bates Michelle
- Bathula Rajaram
- Battersby-Wood Emma
- Bayliss Pauline
- Beadle Hannah
- Bearne Helen
- Beaty Teresa
- Beaves Emily
- Bell Angela
- Bell Jo
- Bell Murdina
- Bellfield Ruth
- Beranova Eva
- Bergin Adrian
- Bhakri Harbens
- Bhalla Ajay
- Bharaj Kiranjit
- Bhargava Maneesh
- Bhaskaran Biju
- Bhatnagar Priya
- Birchall Kathryn
- Birns Jonathan
- Black Toby
- Blades Alex
- Blair Caroline
- Blair Caroline
- Blair Gordon
- Blane Sujata
- Blank Catrin
- Blight Adrian
- Board Joanne
- Board Sarah
- Bokhari Maria
- Bond Kirsty
- Bowring Angela
- Boxall Cherish
- Breeds Joanna
- Brew Helen
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- Stafford Samantha
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- Walker Marion
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- Walker Susannah
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- Wallace Rebecca
- Wallace Rebecca
- Walstow Deborah
- Walter Deborah
- Walters Ashleigh
- Wani Mushtaq
- Ward Deborah
- Wardlaw JM
- Watchurst Caroline
- Waterfield Kelly
- Waterfield Kelly
- Watson Fran
- Waugh Dean
- Webb Tom
- Webber Adam
- Webster Timothy
- Weinling Marie
- Weir Nic
- Weir Pauline
- Welch Angela
- Werring DJ
- Whitcher Alison
- White James
- White Julie
- White PM
- White Susan
- Whiteley WN
- Whiteman Jessica
- Whiteman Jessica
- Whiting Robert
- Whittamore Katherine
- Wiggam Ivan
- Wilding Peter
- Wilkes Gwendoline
- Wilkinson Mark
- Willberry Angela
- Williams Carol
- Williams Rebecca
- Williams-Yesson Barbara
- Willmot Mark
- Wilson David
- Wilson Duncan
- Wilson Jenny
- Wilson Lisa
- Wilson Sarah
- Wiltshire Alison
- Wood Diane
- Wood Edith
- Wood Lisa
- Woodward Stephen
- Wright Fiona
- Wroath Belinda
- Wynter Inez
- Yadava Rajendra
- Yip Brigitte
- Young Andrew
- Zachariah George
- Zahoor Tajammal
- Zoe Mellor
- Publication venue
- 'Elsevier BV'
- Publication date
- 29/06/2019
- Field of study
Background:
Antiplatelet therapy reduces the risk of major vascular events for people with occlusive vascular disease, although it might increase the risk of intracranial haemorrhage. Patients surviving the commonest subtype of intracranial haemorrhage, intracerebral haemorrhage, are at risk of both haemorrhagic and occlusive vascular events, but whether antiplatelet therapy can be used safely is unclear. We aimed to estimate the relative and absolute effects of antiplatelet therapy on recurrent intracerebral haemorrhage and whether this risk might exceed any reduction of occlusive vascular events.
Methods:
The REstart or STop Antithrombotics Randomised Trial (RESTART) was a prospective, randomised, open-label, blinded endpoint, parallel-group trial at 122 hospitals in the UK. We recruited adults (≥18 years) who were taking antithrombotic (antiplatelet or anticoagulant) therapy for the prevention of occlusive vascular disease when they developed intracerebral haemorrhage, discontinued antithrombotic therapy, and survived for 24 h. Computerised randomisation incorporating minimisation allocated participants (1:1) to start or avoid antiplatelet therapy. We followed participants for the primary outcome (recurrent symptomatic intracerebral haemorrhage) for up to 5 years. We analysed data from all randomised participants using Cox proportional hazards regression, adjusted for minimisation covariates. This trial is registered with ISRCTN (number ISRCTN71907627).
Findings:
Between May 22, 2013, and May 31, 2018, 537 participants were recruited a median of 76 days (IQR 29–146) after intracerebral haemorrhage onset: 268 were assigned to start and 269 (one withdrew) to avoid antiplatelet therapy. Participants were followed for a median of 2·0 years (IQR [1·0– 3·0]; completeness 99·3%). 12 (4%) of 268 participants allocated to antiplatelet therapy had recurrence of intracerebral haemorrhage compared with 23 (9%) of 268 participants allocated to avoid antiplatelet therapy (adjusted hazard ratio 0·51 [95% CI 0·25–1·03]; p=0·060). 18 (7%) participants allocated to antiplatelet therapy experienced major haemorrhagic events compared with 25 (9%) participants allocated to avoid antiplatelet therapy (0·71 [0·39–1·30]; p=0·27), and 39 [15%] participants allocated to antiplatelet therapy had major occlusive vascular events compared with 38 [14%] allocated to avoid antiplatelet therapy (1·02 [0·65–1·60]; p=0·92).
Interpretation:
These results exclude all but a very modest increase in the risk of recurrent intracerebral haemorrhage with antiplatelet therapy for patients on antithrombotic therapy for the prevention of occlusive vascular disease when they developed intracerebral haemorrhage. The risk of recurrent intracerebral haemorrhage is probably too small to exceed the established benefits of antiplatelet therapy for secondary prevention
Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial
- Author
- Aberami Chandrakumar
- Abhijit Mate
- Adam Hague
- Adam Webber
- Adrian Barry
- Adrian Bergin
- Adrian Blight
- Adrian Butler
- Adrian Parry-Jones
- Afaq Saulat
- Afaq Saulat
- Afnan Chaudhry
- Afraim Salek-Haddadi
- Aguilar
- Ahamad Hassan
- Ahmad Maatouk
- Ahmed Osman
- Aidan Hutchison
- Aileen McGrath
- Ailsa Fulton
- Aine Wallace
- Ajay Bhalla
- Ajmal Anversha
- Al-Shahi Salman
- Al-Shahi Salman
- Al-Shahi Salman
- Alda Remegoso
- Alex Blades
- Alex Ramshaw
- Alex Shah
- Alexandra Pitt-Ford
- Alfonso Tanate
- Ali Ali
- Ali James
- Alicia Rodgers
- Alison McLoughlin
- Alison Whitcher
- Alison Wiltshire
- Allan MacRaild
- Allan Walker
- Alpha Anthony
- Amanda Buck
- Amanda Hedstrom
- Amanda Hedstrom
- Amanda Smart
- Amber Siddiqui
- Amit Mistri
- Amy Ashton
- Amy Steele
- Anand Nair
- Andrea Hall
- Andrea Ingham
- Andrew Moores
- Andrew Sigsworth
- Andrew Smith
- Andrew Stanners
- Andrew Stone
- Andrew Young
- Anette David
- Angela Bell
- Angela Bowring
- Angela Chamberlain
- Angela Cook
- Angela Dodd
- Angela Stevens
- Angela Welch
- Angela Willberry
- Anita Goff
- Anja Ljubez
- Ann Deary
- Ann Needle
- Anna Verrion
- Anne Hardwick
- Anne Hayes
- Anne Nicolson
- Anne Oshodi
- Anne Suttling
- Annemarie Hunter
- Anoja Rajapakse
- Anthea Parry
- Anthony Byrne
- Anthony Hemsley
- Antony Kenton
- Anu Joyson
- Anwer Siddiqui
- Aparna Pusalkar
- Aravind Manoj
- Arindam Kar
- Arshad Majis
- Arshi Iqbal
- Arumugam Nallasivan
- Arun Singh
- Arunkumar Annamalai
- Aryelly Rodriguez
- Ashish Macaden
- Ashleigh Walters
- Ashraf Ahmed
- Ashraf Nasim
- Audrey Thomson
- Avani Shukla
- Azlisham Mohd Nor
- Azra Banaras
- Baigent
- Balakrishna Kumar
- Baljinder Rai
- Baljit Jagpal
- Bander Dallol
- Barbara Longland
- Barbara Madigan
- Barbara Williams-Yesson
- Barry Moynihan
- Basaam Aweid
- Becky Jupp
- Bejot
- Belinda Wroath
- Bella Richard
- Benjamin Hunt
- Benjamin Hyams
- Benjamin Jackson
- Benjamin Jelley
- Benjamin Tomlinson
- Bernard Esisi
- Bernard Esisi
- Beth Hazel
- Bethan Charles
- Bethan Morse
- Betty Mokoena
- Bev Maund
- Beverley McClelland
- Beverly MacLennan
- Bharath Kumar Cheripelli
- Bhavini Patel
- Biffi
- Biju Bhaskaran
- Bindu Gregory
- Bithi Rahman
- Breffni Keegan
- Brian Clarke
- Brian MacInnes
- Brigid Hairsine
- Brigitte Yip
- Bruno
- Carinna Vickers
- Carla Jordan
- Carmen Constantin
- Carol Denniss
- Carol Graham
- Carol Jeffs
- Carol Williams
- Carole Green
- Carole Hays
- Caroline Bagnall
- Caroline Blair
- Caroline Blair
- Caroline Clarke
- Caroline Clay
- Caroline Crosbie
- Caroline Davies
- Caroline Hogan
- Caroline Lambert
- Caroline Lovelock
- Caroline McGhee
- Caroline Roughan
- Caroline Watchurst
- Cassilda Peixoto
- Catherine Ovington
- Catherine Plewa
- Cathy Mason
- Catrin Blank
- Chakravarthi Rajkumar
- Champa Patel
- Chantel Cox
- Charde Naylor
- Charlotte Barr
- Charlotte Culmsee
- Charlotte Eglinton
- Charlotte Eglinton
- Charlotte Fox
- Charlotte Perkins
- Chelsea Causley
- Cherish Boxall
- Chloe Cox
- Chloe Hughes
- Chloe van Someren
- Chong
- Chris Patterson
- Christian Hansen
- Christina Dickinson
- Christine Dickson
- Christine Kamara
- Christine Kelly
- Christine Lerpiniere
- Christine Lerpiniere
- Christine McAlpine
- Christine Roffe
- Christine Schofield
- Christopher Allen
- Christopher Matthews
- Chukwuka Orefo
- Claire Brown
- Claire Copeland
- Claire Cullen
- Claire Hughes
- Claire James
- Claire Nott
- Claire Nott
- Claire Stephens
- Claire Sutton
- Claire Triscott
- Claire Triscott
- Clare Buckley
- Clare Doyle
- Clare Holmes
- Clark
- CLM Sudlow
- Colin Baigent
- Colin Jenkins
- Connor McGill
- Corinne Pawley
- Counsell
- Damian McArdle
- Daniel Epstein
- Daniel Lasserson
- Daniela Shackcloth
- Danielle Gilmour
- David Broughton
- David Bruce
- David Buchanan
- David Cohen
- David Eveson
- David Jarrett
- David Mangion
- David Minks
- David Ngo
- David Perry
- David Strain
- David Wilson
- Dawn Tomlin
- DE Newby
- Dean Waugh
- Debbie Morgan
- Deborah Howcroft
- Deborah Walstow
- Deborah Walter
- Deborah Ward
- Debs Kelly
- Deepa Jose
- Denise Button
- Denise Donaldson
- Denise Mead
- Dennis
- Derek Esson
- Derek Esson
- Devesh Sinha
- Dheeraj Kalladka
- Diane Gulliver
- Diane Havard
- Diane Wood
- Dinesh Chadha
- Dinesh Tryambake
- Ding
- Dionne Hove
- Dipankar Dutta
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- Sandip Ghosh
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- Sarah O'Toole
- Sarah Ross
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- Sarah Thomas
- Sarah Thornthwaite
- Sarah Trippier
- Sarah Wilson
- Sean Mcauley
- Senthil Raghunathan
- Seona Burgess
- Shagufta Khan
- Shahrzad Shahmehri
- Shanni McDonald
- Shannon Amoils
- Sharon Johnson
- Sharon Storton
- Sharon Tysoe
- Sheila Mashate
- Sheila Nyabadza
- Shelley Treadwell
- Shez Feerick
- Shrivakumar Krishnamoorthy
- Shuja Punekar
- Shuna Egerton
- Shyam Kelavkar
- Silvie Davies
- Simon Hervey
- Simon Sharpe
- Simon Smith
- Simone Ivatts
- Sindhu Rashmi
- Siobhan Kelly
- Sissy Ispoglou
- Skarlet Markova
- Skelton Miriam
- Sofia Dima
- Sonia Raj
- Sophie Newton
- Sreeman Andole
- Srikanth Chenna
- Stacey Valentine
- Stefan Schwarz
- Steiner
- Steinhubl
- Stephanie Jones
- Stephanie Lee
- Stephanie McCann
- Stephanie Stevens
- Stephen Duberley
- Stephen Woodward
- Steve Buckle
- Steve Buckle
- Stuart Maguire
- Stuart Symonds
- Sue Evans
- Sue Lyjko
- Suheil Ponnambath
- Suja Cherian
- Sujata Blane
- Sulaiman Sultan
- Susan Clayton
- Susan Crawford
- Susan Downham
- Susan Maiden
- Susan McDonald
- Susan O'Connell
- Susan Pound
- Susan Szabo
- Susan Thompson
- Susan Tucker
- Susan White
- Susannah Walker
- Suzanne Lucas
- Suzanne Ragab
- Suzanne Tauro
- Swapna Kunhunny
- Sweni Shah
- Syed Haider
- Tajammal Zahoor
- Talal Al-Mayhani
- Talat Anjum
- Tanya Ingram
- Tara Lawrence
- Tarn Nozedar
- Tatiana Garcia
- Tatjana Roganova
- Temi Adedoyin
- Teo
- Teresa Beaty
- Teresa Thompson
- Terry Jones
- Thayalini Loganathan
- Thomas Gattringer
- Thomas Harrison
- Tim Cassidy
- Timothy England
- Timothy Webster
- Toby Black
- Tolu Adesina
- Tom Hughes
- Tom Webb
- Tony Rudd
- Tracey Cosier
- Tracey Dobson
- Tracy Fuller
- Tracy Marsden
- Tressy Pitt-Kerby
- Una Poultney
- Ursula Schulz
- Usman Khan
- Uzma Khan
- Val Jones
- Valerie Gott
- Valerie Hogg
- van Asch
- Vanessa Pressly
- Varthi Sukdeo
- Vasileios Papavasileiou
- Venetia Vettimootal Johnson
- Vera Cvoro
- Vicky Taylor
- Victoria Adell
- Victoria Little
- Victoria O'Loughlin
- Victoria Sutton
- Victoria Tilley
- Vidya Baliga
- Vinh Nguyen
- Vinodh Krishnamurthy
- Wilma Smith
- WN Whiteley
- Wong
- Wood
- Xuya Huang
- Yasmin Harrington-Davies
- Yogish Joshi
- Yogish Pai
- Yolanda Baird
- Zhe Law
- Zin Naing
- Publication venue
- 'Elsevier BV'
- Publication date
- 21/05/2019
- Field of study
BACKGROUND: Antiplatelet therapy reduces the risk of major vascular events for people with occlusive vascular disease, although it might increase the risk of intracranial haemorrhage. Patients surviving the commonest subtype of intracranial haemorrhage, intracerebral haemorrhage, are at risk of both haemorrhagic and occlusive vascular events, but whether antiplatelet therapy can be used safely is unclear. We aimed to estimate the relative and absolute effects of antiplatelet therapy on recurrent intracerebral haemorrhage and whether this risk might exceed any reduction of occlusive vascular events. METHODS: The REstart or STop Antithrombotics Randomised Trial (RESTART) was a prospective, randomised, open-label, blinded endpoint, parallel-group trial at 122 hospitals in the UK. We recruited adults (≥18 years) who were taking antithrombotic (antiplatelet or anticoagulant) therapy for the prevention of occlusive vascular disease when they developed intracerebral haemorrhage, discontinued antithrombotic therapy, and survived for 24 h. Computerised randomisation incorporating minimisation allocated participants (1:1) to start or avoid antiplatelet therapy. We followed participants for the primary outcome (recurrent symptomatic intracerebral haemorrhage) for up to 5 years. We analysed data from all randomised participants using Cox proportional hazards regression, adjusted for minimisation covariates. This trial is registered with ISRCTN (number ISRCTN71907627). FINDINGS: Between May 22, 2013, and May 31, 2018, 537 participants were recruited a median of 76 days (IQR 29-146) after intracerebral haemorrhage onset: 268 were assigned to start and 269 (one withdrew) to avoid antiplatelet therapy. Participants were followed for a median of 2·0 years (IQR [1·0- 3·0]; completeness 99·3%). 12 (4%) of 268 participants allocated to antiplatelet therapy had recurrence of intracerebral haemorrhage compared with 23 (9%) of 268 participants allocated to avoid antiplatelet therapy (adjusted hazard ratio 0·51 [95% CI 0·25-1·03]; p=0·060). 18 (7%) participants allocated to antiplatelet therapy experienced major haemorrhagic events compared with 25 (9%) participants allocated to avoid antiplatelet therapy (0·71 [0·39-1·30]; p=0·27), and 39 [15%] participants allocated to antiplatelet therapy had major occlusive vascular events compared with 38 [14%] allocated to avoid antiplatelet therapy (1·02 [0·65-1·60]; p=0·92). INTERPRETATION: These results exclude all but a very modest increase in the risk of recurrent intracerebral haemorrhage with antiplatelet therapy for patients on antithrombotic therapy for the prevention of occlusive vascular disease when they developed intracerebral haemorrhage. The risk of recurrent intracerebral haemorrhage is probably too small to exceed the established benefits of antiplatelet therapy for secondary prevention. FUNDING: British Heart Foundation
Measurement of the charge asymmetry in top-quark pair production in the lepton-plus-jets final state in pp collision data at s=8TeV with the ATLAS detector
- Author
- Abbott Brad
- Abdallah Jalal
- Abdinov Ovsat
- Aben Rosemarie
- Abolins Maris
- AbouZeid Ossama
- Abramowicz Halina
- Abreu Henso
- Abreu Ricardo
- Abulaiti Yiming
- Acharya Bobby Sami
- Adamczyk Leszek
- Adams David
- Adelman Jahred
- Adomeit Stefanie
- Adye Tim
- Affolder Tony
- Agatonovic-Jovin Tatjana
- Agricola Johannes
- Aguilar-Saavedra Juan Anton
- Ahlen Steven
- Ahmadov Faig
- Aielli Giulio
- Akerstedt Henrik
- Akimov Andrei
- Alberghi Gian Luigi
- Albert Justin
- Albrand Solveig
- Alconada Verzini Maria Jose
- Aleksa Martin
- Aleksandrov Igor
- Alexa Calin
- Alexander Gideon
- Alexopoulos Theodoros
- Alhroob Muhammad
- Alimonti Gianluca
- Alio Lion
- Alison John
- Alkire Steven Pat
- Allbrooke Benedict
- Allport Phillip
- Aloisio Alberto
- Alonso Alejandro
- Alonso Francisco
- Alpigiani Cristiano
- Altheimer Andrew Dav
- Alvarez Gonzalez Barbara
- Alviggi Mariagrazi
- Amadio Brian Thom
- Amako Katsuya
- Amaral Coutinho Yara
- Amelung Christoph
- Amidei Dante
- Amor Dos Santos Susana Pat
- Amorim Antonio
- Amoroso Simone
- Amram Nir
- Amundsen Glenn
- Anastopoulos Christos
- Ancu Lucian Ste
- Andari Nansi
- Andeen Timothy
- Anders Christoph
- Anders Gabriel
- Anders John Kenne
- Anderson Kelby
- Andreazza Attilio
- Andrei George Vic
- Angelidakis Stylianos
- Angelozzi Ivan
- Anger Philipp
- Angerami Aaron
- Anghinolfi Francis
- Anisenkov Alexey
- Anjos Nuno
- Annovi Alberto
- Antonelli Mario
- Antonov Alexey
- Antos Jaroslav
- Anulli Fabio
- Aoki Masato
- Aperio Bella Ludovica
- Arabidze Giorgi
- Arai Yasuo
- Araque Juan Pedro
- Arce Ayana
- Arduh Francisco
- Arguin Jean-Franc
- Argyropoulos Spyridon
- Arik Metin
- Armbruster Aaron Jame
- Arnaez Olivier
- Arnold Hannah
- Arratia Miguel
- Arslan Ozan
- Artamonov Andrei
- Artoni Giacomo
- Asai Shoji
- Asbah Nedaa
- Ashkenazi Adi
- Asquith Lily
- Assamagan Ketevi
- Astalos Robert
- Atkinson Markus
- Atlay Naim Bora
- Augsten Kamil
- Aurousseau Mathieu
- Avolio Giuseppe
- Axen Bradley
- Ayoub Mohamad Ka
- Azuelos Georges
- Baak Max
- Baas Alessandra
- Baca Matthew Jo
- Bacci Cesare
- Bachacou Henri
- Bachas Konstantin
- Backes Moritz
- Backhaus Malte
- Bagiacchi Paolo
- Bagnaia Paolo
- Bai Yu
- Bain Travis
- Baines John
- Baker Oliver Kei
- Baldin Evgenii
- Balek Petr
- Balestri Thomas
- Balli Fabrice
- Balunas William Ke
- Banas Elzbieta
- Banerjee Swagato
- Bannoura Arwa A E
- Barak Liron
- Barberio Elisabetta
- Barberis Dario
- Barbero Marlon
- Barillari Teresa
- Barisonzi Marcello
- Barklow Timothy
- Barlow Nick
- Barnes Sarah Loui
- Barnett Bruce
- Barnett Michael
- Barnovska Zuzana
- Baroncelli Antonio
- Barone Gaetano
- Barr Alan
- Barreiro Guimarães da Costa João
- Barreiro Fernando
- Barros do Vale Maria Alin
- Bartoldus Rainer
- Barton Adam Edwar
- Bartos Pavol
- Basalaev Artem
- Bassalat Ahmed
- Basye Austin
- Bates Richard
- Batista Santiago J
- Batley Richard
- Battaglia Marco
- Bauce Matteo
- Bauer Florian
- Bawa Harinder S
- Beacham James Bake
- Beattie Michael Da
- Beau Tristan
- Beauchemin Pierre-Hug
- Beccherle Roberto
- Bechtle Philip
- Beck Hans Peter
- Becker Kathrin
- Becker Maurice
- Beckingham Matthew
- Becot Cyril
- Beddall Andrew
- Beddall Ayda
- Bednyakov Vadim
- Bee Christophe
- Beemster Lars
- Beermann Thomas
- Begel Michael
- Behr Janna Kath
- Belanger-Champagne Camille
- Bell William
- Bella Gideon
- Bellagamba Lorenzo
- Bellerive Alain
- Bellomo Massimilia
- Belotskiy Konstantin
- Beltramello Olga
- Benary Odette
- Benchekroun Driss
- Bender Michael
- Bendtz Katarina
- Benekos Nektarios
- Benhammou Yan
- Benhar Noccioli Eleonora
- Benitez Garcia Jorge-Arma
- Benjamin Douglas
- Bensinger James
- Bentvelsen Stan
- Beresford Lydia
- Beretta Matteo
- Berge David
- Bergeaas Kuutmann Elin
- Berger Nicolas
- Berghaus Frank
- Beringer Jürg
- Bernard Clare
- Bernard Nathan Rog
- Bernius Catrin
- Bernlochner Florian Ur
- Berry Tracey
- Berta Peter
- Bertella Claudia
- Bertoli Gabriele
- Bertolucci Federico
- Bertsche Carolyn
- Bertsche David
- Besana Maria Ilar
- Besjes Geert-Jan
- Bessidskaia Bylund Olga
- Bessner Martin Flo
- Besson Nathalie
- Betancourt Christophe
- Bethke Siegfried
- Bevan Adrian Joh
- Bhimji Wahid
- Bianchi Riccardo-M
- Bianchini Louis
- Bianco Michele
- Biebel Otmar
- Biedermann Dustin
- Bieniek Stephen Pa
- Biesuz Nicolo Vla
- Biglietti Michela
- Bilbao De Mendizabal Javier
- Bilokon Halina
- Bindi Marcello
- Binet Sebastien
- Bingul Ahmet
- Bini Cesare
- Biondi Silvia
- Bjergaard David Mart
- Black Curtis
- Black James
- Black Kevin
- Blackburn Daniel
- Blair Robert
- Blanchard Jean-Bapti
- Blanco Jacobo Eze
- Blazek Tomas
- Bloch Ingo
- Blocker Craig
- Blum Walter
- Blumenschein Ulrike
- Blunier Sylvain
- Bobbink Gerjan
- Bobrovnikov Victor
- Bocchetta Simona Ser
- Bocci Andrea
- Bock Christophe
- Boehler Michael
- Bogaerts Joannes An
- Bogavac Danijela
- Bogdanchikov Alexander
- Bohm Christian
- Boisvert Veronique
- Bold Tomasz
- Boldea Venera
- Boldyrev Alexey
- Bomben Marco
- Bona Marcella
- Boonekamp Maarten
- Borisov Anatoly
- Borissov Guennadi
- Borroni Sara
- Bortfeldt Jonathan
- Bortolotto Valerio
- Bos Kors
- Boscherini Davide
- Bosman Martine
- Boudreau Joseph
- Bouffard Julian
- Bouhova-Thacker Evelina Va
- Boumediene Djamel Edd
- Bourdarios Claire
- Bousson Nicolas
- Boutle Sarah Kate
- Boveia Antonio
- Boyd James
- Boyko Igor
- Bozic Ivan
- Bracinik Juraj
- Brandt Andrew
- Brandt Gerhard
- Brandt Oleg
- Bratzler Uwe
- Brau Benjamin
- Brau James
- Braun Helmut
- Breaden Madden William Dm
- Brendlinger Kurt
- Brennan Amelia Jea
- Brenner Lydia
- Brenner Richard
- Bressler Shikma
- Bristow Timothy Mi
- Britton Dave
- Britzger Daniel
- Brochu Frederic
- Brock Ian
- Brock Raymond
- Bronner Johanna
- Brooijmans Gustaaf
- Brooks Timothy
- Brooks William
- Brosamer Jacquelyn
- Brost Elizabeth
- Bruckman de Renstrom Pawel
- Bruncko Dusan
- Bruneliere Renaud
- Bruni Alessia
- Bruni Graziano
- Bruschi Marco
- Bruscino Nello
- Bryngemark Lene
- Buanes Trygve
- Buat Quentin
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- Hasegawa Yoji
- Hasib A
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- Haug Sigve
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- Hawkings Richard Jo
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- Wanotayaroj Chaowaroj
- Warburton Andreas
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- Weber Stefan Wol
- Webster Jordan S
- Weidberg Anthony
- Weinert Benjamin
- Weingarten Jens
- Weiser Christian
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- Wickens Fred
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- Wiik-Fuchs Liv Antje
- Wildauer Andreas
- Wilkens Henric Geo
- Williams Hugh
- Williams Sarah
- Willis Christophe
- Willocq Stephane
- Wilson Alan
- Wilson John
- Wingerter-Seez Isabelle
- Winklmeier Frank
- Winter Benedict T
- Wittgen Matthias
- Wittkowski Josephine
- Wollstadt Simon Jako
- Wolter Marcin Wla
- Wolters Helmut
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- Wotschack Jorg
- Woudstra Martin
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- Wu Miles
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- Wyatt Terry Rich
- Wynne Benjamin
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- Xu Da
- Xu Lailin
- Yabsley Bruce
- Yacoob Sahal
- Yakabe Ryota
- Yamada Miho
- Yamaguchi Daiki
- Yamaguchi Yohei
- Yamamoto Akira
- Yamamoto Shimpei
- Yamanaka Takashi
- Yamauchi Katsuya
- Yamazaki Yuji
- Yan Zhen
- Yang Haijun
- Yang Hongtao
- Yang Yi
- Yao Weiming
- Yap Yee Chinn
- Yasu Yoshiji
- Yatsenko Elena
- Yau Wong Kaven Henr
- Ye Jingbo
- Ye Shuwei
- Yeletskikh Ivan
- Yen Andy L
- Yildirim Eda
- Yorita Kohei
- Yoshida Rikutaro
- Yoshihara Keisuke
- Young Charles
- Young Christophe
- Youssef Saul
- Yu David Ren-
- Yu Jaehoon
- Yu Jiaming
- Yu Jie
- Yuan Li
- Yuen Stephanie
- Yurkewicz Adam
- Yusuff Imran
- Zabinski Bartlomiej
- Zaidan Remi
- Zaitsev Alexander
- Zalieckas Justas
- Zaman Aungshuman
- Zambito Stefano
- Zanello Lucia
- Zanzi Daniele
- Zeitnitz Christian
- Zeman Martin
- Zemla Andrzej
- Zeng Qi
- Zengel Keith
- Zenin Oleg
- Zerwas Dirk
- Zhang Dongliang
- Zhang Fangzhou
- Zhang Guangyi
- Zhang Huijun
- Zhang Jinlong
- Zhang Lei
- Zhang Ruiqi
- Zhang Xueyao
- Zhang Zhiqing
- Zhao Xiandong
- Zhao Yongke
- Zhao Zhengguo
- Zhemchugov Alexey
- Zhong Jiahang
- Zhou Bing
- Zhou Chen
- Zhou Lei
- Zhou Li
- Zhou Mingliang
- Zhou Ning
- Zhu Cheng Guan
- Zhu Hongbo
- Zhu Junjie
- Zhu Yingchun
- Zhuang Xuai
- Zhukov Konstantin
- Zibell Andre
- Zieminska Daria
- Zimine Nikolai
- Zimmermann Christoph
- Zimmermann Stephanie
- Zinonos Zinonas
- Zinser Markus
- Ziolkowski Michael
- Zobernig Georg
- Zoccoli Antonio
- zur Nedden Martin
- Zurzolo Giovanni
- Zwalinski Lukasz
- Åkesson Torsten Pa
- Åsman Barbro
- Ženiš Tibor
- Živković Lidija
- Άlvarez Piqueras Damián
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 19/02/2016
- Field of study
Search for single production of vector-like quarks decaying into Wb in pp collisions at s=8 TeV with the ATLAS detector
- Author
- Abbott Brad
- Abdallah Jalal
- Abdinov Ovsat
- Abeloos Baptiste
- Aben Rosemarie
- Abolins Maris
- AbouZeid Ossama
- Abramowicz Halina
- Abreu Henso
- Abreu Ricardo
- Abulaiti Yiming
- Acharya Bobby Sami
- Adamczyk Leszek
- Adams David
- Adelman Jahred
- Adomeit Stefanie
- Adye Tim
- Affolder Tony
- Agatonovic-Jovin Tatjana
- Agricola Johannes
- Aguilar-Saavedra Juan Anton
- Ahlen Steven
- Ahmadov Faig
- Aielli Giulio
- Akerstedt Henrik
- Akimov Andrei
- Alberghi Gian Luigi
- Albert Justin
- Albrand Solveig
- Alconada Verzini Maria Jose
- Aleksa Martin
- Aleksandrov Igor
- Alexa Calin
- Alexander Gideon
- Alexopoulos Theodoros
- Alhroob Muhammad
- Alimonti Gianluca
- Alio Lion
- Alison John
- Alkire Steven Pat
- Allbrooke Benedict
- Allen Benjamin W
- Allport Phillip
- Aloisio Alberto
- Alonso Alejandro
- Alonso Francisco
- Alpigiani Cristiano
- Alvarez Gonzalez Barbara
- Alviggi Mariagrazi
- Amadio Brian Thom
- Amako Katsuya
- Amaral Coutinho Yara
- Amelung Christoph
- Amidei Dante
- Amor Dos Santos Susana Pat
- Amorim Antonio
- Amoroso Simone
- Amram Nir
- Amundsen Glenn
- Anastopoulos Christos
- Ancu Lucian Ste
- Andari Nansi
- Andeen Timothy
- Anders Christoph
- Anders Gabriel
- Anders John Kenne
- Anderson Kelby
- Andreazza Attilio
- Andrei George Vic
- Angelidakis Stylianos
- Angelozzi Ivan
- Anger Philipp
- Angerami Aaron
- Anghinolfi Francis
- Anisenkov Alexey
- Anjos Nuno
- Annovi Alberto
- Antonelli Mario
- Antonov Alexey
- Antos Jaroslav
- Anulli Fabio
- Aoki Masato
- Aperio Bella Ludovica
- Arabidze Giorgi
- Arai Yasuo
- Araque Juan Pedro
- Arce Ayana
- Arduh Francisco
- Arguin Jean-Franc
- Argyropoulos Spyridon
- Arik Metin
- Armbruster Aaron Jame
- Arnaez Olivier
- Arnold Hannah
- Arratia Miguel
- Arslan Ozan
- Artamonov Andrei
- Artoni Giacomo
- Artz Sebastian
- Asai Shoji
- Asbah Nedaa
- Ashkenazi Adi
- Asquith Lily
- Assamagan Ketevi
- Astalos Robert
- Atkinson Markus
- Atlay Naim Bora
- Augsten Kamil
- Avolio Giuseppe
- Axen Bradley
- Ayoub Mohamad Ka
- Azuelos Georges
- Baak Max
- Baas Alessandra
- Baca Matthew Jo
- Bachacou Henri
- Bachas Konstantin
- Backes Moritz
- Backhaus Malte
- Bagiacchi Paolo
- Bagnaia Paolo
- Bai Yu
- Baines John
- Baker Oliver Kei
- Baldin Evgenii
- Balek Petr
- Balestri Thomas
- Balli Fabrice
- Balunas William Ke
- Banas Elzbieta
- Banerjee Swagato
- Bannoura Arwa A E
- Barak Liron
- Barberio Elisabetta
- Barberis Dario
- Barbero Marlon
- Barillari Teresa
- Barisonzi Marcello
- Barklow Timothy
- Barlow Nick
- Barnes Sarah Loui
- Barnett Bruce
- Barnett Michael
- Barnovska Zuzana
- Baroncelli Antonio
- Barone Gaetano
- Barr Alan
- Barranco Navarro Laura
- Barreiro Guimarães da Costa João
- Barreiro Fernando
- Barros do Vale Maria Alin
- Bartoldus Rainer
- Barton Adam Edwar
- Bartos Pavol
- Basalaev Artem
- Bassalat Ahmed
- Basye Austin
- Bates Richard
- Batista Santiago J
- Batley Richard
- Battaglia Marco
- Bauce Matteo
- Bauer Florian
- Bawa Harinder S
- Beacham James Bake
- Beattie Michael Da
- Beau Tristan
- Beauchemin Pierre-Hug
- Beccherle Roberto
- Bechtle Philip
- Beck Hans~Peter
- Becker Kathrin
- Becker Maurice
- Beckingham Matthew
- Becot Cyril
- Beddall Andrew
- Beddall Ayda
- Bednyakov Vadim
- Bedognetti Matteo
- Bee Christophe
- Beemster Lars
- Beermann Thomas
- Begel Michael
- Behr Janna Kath
- Belanger-Champagne Camille
- Bell William
- Bella Gideon
- Bellagamba Lorenzo
- Bellerive Alain
- Bellomo Massimilia
- Belotskiy Konstantin
- Beltramello Olga
- Benary Odette
- Benchekroun Driss
- Bender Michael
- Bendtz Katarina
- Benekos Nektarios
- Benhammou Yan
- Benhar Noccioli Eleonora
- Benitez Garcia Jorge-Arma
- Benjamin Douglas
- Bensinger James
- Bentvelsen Stan
- Beresford Lydia
- Beretta Matteo
- Berge David
- Bergeaas Kuutmann Elin
- Berger Nicolas
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- Beringer Jürg
- Bernard Clare
- Bernard Nathan Rog
- Bernius Catrin
- Bernlochner Florian Ur
- Berry Tracey
- Berta Peter
- Bertella Claudia
- Bertoli Gabriele
- Bertolucci Federico
- Bertsche Carolyn
- Bertsche David
- Besjes Geert-Jan
- Bessidskaia Bylund Olga
- Bessner Martin Flo
- Besson Nathalie
- Betancourt Christophe
- Bethke Siegfried
- Bevan Adrian Joh
- Bhimji Wahid
- Bianchi Riccardo-M
- Bianchini Louis
- Bianco Michele
- Biebel Otmar
- Biedermann Dustin
- Biesuz Nicolo Vla
- Biglietti Michela
- Bilbao De Mendizabal Javier
- Bilokon Halina
- Bindi Marcello
- Binet Sebastien
- Bingul Ahmet
- Bini Cesare
- Biondi Silvia
- Bjergaard David Mart
- Black Curtis
- Black James
- Black Kevin
- Blackburn Daniel
- Blair Robert
- Blanchard Jean-Bapti
- Blanco Jacobo Eze
- Blazek Tomas
- Bloch Ingo
- Blocker Craig
- Blum Walter
- Blumenschein Ulrike
- Blunier Sylvain
- Bobbink Gerjan
- Bobrovnikov Victor
- Bocchetta Simona Ser
- Bocci Andrea
- Bock Christophe
- Boehler Michael
- Boerner Daniela
- Bogaerts Joannes An
- Bogavac Danijela
- Bogdanchikov Alexander
- Bohm Christian
- Boisvert Veronique
- Bold Tomasz
- Boldea Venera
- Boldyrev Alexey
- Bomben Marco
- Bona Marcella
- Boonekamp Maarten
- Borisov Anatoly
- Borissov Guennadi
- Bortfeldt Jonathan
- Bortolotto Valerio
- Bos Kors
- Boscherini Davide
- Bosman Martine
- Boudreau Joseph
- Bouffard Julian
- Bouhova-Thacker Evelina Va
- Boumediene Djamel Edd
- Bourdarios Claire
- Bousson Nicolas
- Boutle Sarah Kate
- Boveia Antonio
- Boyd James
- Boyko Igor
- Bracinik Juraj
- Brandt Andrew
- Brandt Gerhard
- Brandt Oleg
- Bratzler Uwe
- Brau Benjamin
- Brau James
- Braun Helmut
- Breaden Madden William Dm
- Brendlinger Kurt
- Brennan Amelia Jea
- Brenner Lydia
- Brenner Richard
- Bressler Shikma
- Bristow Timothy Mi
- Britton Dave
- Britzger Daniel
- Brochu Frederic
- Brock Ian
- Brock Raymond
- Brooijmans Gustaaf
- Brooks Timothy
- Brooks William
- Brosamer Jacquelyn
- Brost Elizabeth
- Bruckman de Renstrom Pawel
- Bruncko Dusan
- Bruneliere Renaud
- Bruni Alessia
- Bruni Graziano
- Brunt Benjamin
- Bruschi Marco
- Bruscino Nello
- Bryant Patrick
- Bryngemark Lene
- Buanes Trygve
- Buat Quentin
- Buchholz Peter
- Buckley Andrew
- Budagov Ioulian
- Buehrer Felix
- Bugge Lars
- Bugge Magnar Kop
- Bulekov Oleg
- Bullock Daniel
- Burckhart Helfried
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- Burghgrave Blake
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- Buttar Craig
- Butterworth Jonathan
- Butti Pierfrance
- Buttinger William
- Buzatu Adrian
- Buzykaev Aleksey
- Büscher Daniel
- Büscher Volker
- Cabrera Urbán Susana
- Caforio Davide
- Cairo Valentina
- Cakir Orhan
- Calace Noemi
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- Calderini Giovanni
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- Caloba Luiz
- Calvet David
- Calvet Samuel
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- Camacho Toro Reina
- Camarda Stefano
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- Cameron David
- Caminal Armadans Roger
- Camincher Clement
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- Canale Vincenzo
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- Caprini Irinel
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- Capua Marcella
- Caputo Regina
- Carbone Ryne Micha
- Cardarelli Roberto
- Cardillo Fabio
- Carli Tancredi
- Carlino Gianpaolo
- Carminati Leonardo
- Caron Sascha
- Carquin Edson
- Carrillo-Montoya German D
- Carter Janet
- Carvalho João
- Casadei Diego
- Casado Maria Pila
- Casolino Mirkoanton
- Casper David Will
- Castaneda-Miranda Elizabeth
- Castelli Angelanton
- Castillo Gimenez Victoria
- Castro Nuno Filip
- Catinaccio Andrea
- Catmore James
- Cattai Ariella
- Caudron Julien
- Cavaliere Viviana
- Cavalli Donatella
- Cavalli-Sforza Matteo
- Cavasinni Vincenzo
- Ceradini Filippo
- Cerda Alberich Leonor
- Cerio Benjamin
- Cerri Alessandro
- Cerrito Lucio
- Cerutti Fabio
- Cerv Matevz
- Cervelli Alberto
- Cetin Serkant Al
- Chafaq Aziz
- Chakraborty Dhiman
- Chalupkova Ina
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- Chang Philip
- Chapman John Derek
- Charlton Dave
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- Chavez Barajas Carlos Alb
- Che Siinn
- Cheatham Susan
- Chegwidden Andrew
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- Chekulaev Sergey
- Chelkov Gueorgui
- Chelstowska Magda Anna
- Chen Chunhui
- Chen Hucheng
- Chen Karen
- Chen Shenjian
- Chen Shion
- Chen Xin
- Chen Ye
- Cheng Hok Chuen
- Cheng Yangyang
- Cheplakov Alexander
- Cheremushkina Evgenia
- Cherkaoui El Moursli Rajaa
- Chernyatin Valeriy
- Cheu Elliott
- Chevalier Laurent
- Chiarella Vitaliano
- Chiarelli Giorgio
- Chiodini Gabriele
- Chisholm Andrew
- Chislett Rebecca Th
- Chitan Adrian
- Chizhov Mihail
- Choi Kyungeon
- Chouridou Sofia
- Chow Bonnie Kar
- Christodoulou Valentinos
- Chromek-Burckhart Doris
- Chudoba Jiri
- Chuinard Annabelle
- Chwastowski Janusz
- Chytka Ladislav
- Ciapetti Guido
- Ciftci Abbas Kena
- Cinca Diane
- Cindro Vladimir
- Cioara Irina Anto
- Ciocio Alessandra
- Cirotto Francesco
- Citron Zvi Hirsh
- Ciubancan Mihai
- Clark Allan G
- Clark Brian Lee
- Clark Philip Jam
- Clarke Robert
- Clement Christophe
- Coadou Yann
- Cobal Marina
- Coccaro Andrea
- Cochran James H
- Coffey Laurel
- Colasurdo Luca
- Cole Brian
- Cole Stephen
- Colijn Auke-Piete
- Collot Johann
- Colombo Tommaso
- Compostella Gabriele
- Conde Muiño Patricia
- Coniavitis Elias
- Connell Simon Henr
- Connelly Ian
- Consorti Valerio
- Constantinescu Serban
- Conta Claudio
- Conti Geraldine
- Conventi Francesco
- Cooke Mark
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- Cooper-Sarkar Amanda
- Cornelissen Thijs
- Corradi Massimo
- Corriveau Francois
- Corso-Radu Alina
- Cortes-Gonzalez Arely
- Cortiana Giorgio
- Costa Giuseppe
- Costa María Jos
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- Cottin Giovanna
- Cowan Glen
- Cox Brian
- Cranmer Kyle
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- Cree Graham
- Crescioli Francesco
- Cribbs Wayne Alle
- Crispin Ortuzar Mireia
- Cristinziani Markus
- Croft Vince
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- Crépé-Renaudin Sabine
- Cuhadar Donszelmann Tulay
- Cummings Jane
- Curatolo Maria
- Cuthbert Cameron
- Czirr Hendrik
- Czodrowski Patrick
- Cúth Jakub
- D'Auria Saverio
- D'Onofrio Monica
- Da Cunha Sargedas De Sousa Mario Jose
- Da Via Cinzia
- Dabrowski Wladyslaw
- Dafinca Alexandru
- Dai Tiesheng
- Dale Orjan
- Dallaire Frederick
- Dallapiccola Carlo
- Dam Mogens
- Dandoy Jeffrey Ro
- Dang Nguyen Phu
- Daniells Andrew Chr
- Danninger Matthias
- Dano Hoffmann Maria
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- de Asmundis Riccardo
- De Benedetti Abraham
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- De Kaushik
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- Dewhurst Alastair
- Dhaliwal Saminder
- Di Ciaccio Anna
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- Di Domenico Antonio
- Di Donato Camilla
- Di Girolamo Alessandro
- Di Girolamo Beniamino
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- Ye Shuwei
- Yeletskikh Ivan
- Yen Andy L
- Yildirim Eda
- Yorita Kohei
- Yoshida Rikutaro
- Yoshihara Keisuke
- Young Charles
- Young Christophe
- Youssef Saul
- Yu David Ren-
- Yu Jaehoon
- Yu Jiaming
- Yu Jie
- Yuan Li
- Yuen Stephanie
- Yusuff Imran
- Zabinski Bartlomiej
- Zaidan Remi
- Zaitsev Alexander
- Zakharchuk Nataliia
- Zalieckas Justas
- Zaman Aungshuman
- Zambito Stefano
- Zanello Lucia
- Zanzi Daniele
- Zeitnitz Christian
- Zeman Martin
- Zemla Andrzej
- Zeng Jian Cong
- Zeng Qi
- Zengel Keith
- Zenin Oleg
- Zerwas Dirk
- Zhang Dongliang
- Zhang Fangzhou
- Zhang Guangyi
- Zhang Huijun
- Zhang Jinlong
- Zhang Lei
- Zhang Rui
- Zhang Ruiqi
- Zhang Xueyao
- Zhang Zhiqing
- Zhao Xiandong
- Zhao Yongke
- Zhao Zhengguo
- Zhemchugov Alexey
- Zhong Jiahang
- Zhou Bing
- Zhou Chen
- Zhou Lei
- Zhou Li
- Zhou Mingliang
- Zhou Ning
- Zhu Cheng Guan
- Zhu Hongbo
- Zhu Junjie
- Zhu Yingchun
- Zhuang Xuai
- Zhukov Konstantin
- Zibell Andre
- Zieminska Daria
- Zimine Nikolai
- Zimmermann Christoph
- Zimmermann Stephanie
- Zinonos Zinonas
- Zinser Markus
- Ziolkowski Michael
- Zobernig Georg
- Zoccoli Antonio
- zur Nedden Martin
- Zurzolo Giovanni
- Zwalinski Lukasz
- Åkesson Torsten Pa
- Åsman Barbro
- Ženiš Tibor
- Živković Lidija
- Άlvarez Piqueras Damián
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 08/08/2016
- Field of study