56 research outputs found
A fluvial geomorphological study of river rehabilitation in the Kouga region, Eastern Cape
The Kouga Riparian Rehabilitation Project (KRRP) is seen as a pilot rehabilitation project in the Kouga region that is heavily invaded with Acacia mearnsii along the riparian zones of many mountain streams. Clearing of these black wattles and re-planting of indigenous vegetation are imperative to rehabilitation efforts. In this context, two invaded catchments were identified - the Baviaans and the Heuningnes. The aim of this research is to characterise the effects that the woody alien invasive Acacia mearnsii has had on the river channel morphology of the Baviaans and Heuningnes Rivers. A desktop and initial field analysis of the relevant study area catchments was completed. This was followed by a comparison of the channel morphology of the various study channel reaches using fixed channel transects. Ecological resource quality objectives (RQOs) for river rehabilitation from a fluvial geomorphological viewpoint were then established. A long-term monitoring protocol to assess whether or not these RQOs will be achieved was recommended. Follow-up channel transects were measured post wattle clearance in the Baviaans and short-term (<2yrs) changes in channel form were described. Differences in terms of the effect of Acacia mearnsii on channel form were then interpreted by direct comparison and through statistical analysis. Results indicate a number of significant differences between those channels impacted by black wattle infestation and those channels seen as unimpacted and natural. Short-term changes (<2yrs) that occurred within the study period post Baviaans wattle clearance were shown to be minimal for channel form as well as for bed material. The lack of any clear relationship or explanation between channel form and other channel controls suggests vegetation as the primary control. Vegetation, specifically the invasive alien vegetation, is the key controlling variable acting on channel form in the two study catchments
Association Between ECG Abnormalities and Fatal Cardiovascular Disease Among Patients With and Without Severe Mental Illness
BACKGROUND: ECG abnormalities are associated with adverse outcomes in the general population, but their prognostic significance in severe mental illness (SMI) remains unexplored. We investigated associations between no, minor, and major ECG abnormalities and fatal cardiovascular disease (CVD) among patients with SMI compared with controls without mental illness. METHODS AND RESULTS: We cross-linked data from Danish nationwide registries and included primary care patients with digital ECGs from 2001 to 2015. Patients had SMI if they were diagnosed with schizophrenia, bipolar disorder, or severe depression before ECG recording. Controls were required to be without any prior mental illness or psychotropic medication use. Fatal CVD was assessed using hazard ratios (HRs) with 95% CIs and standardized 10-year absolute risks. Of 346 552 patients, 10 028 had SMI (3%; median age, 54 years; male, 45%), and 336 524 were controls (97%; median age, 56 years; male, 48%). We observed an interaction between SMI and ECG abnormalities on fatal CVD (P<0.001). Severe mental illness was associated with fatal CVD across no (HR, 2.17; 95% CI, 1.95–2.43), minor (HR, 1.90; 95% CI, 1.49–2.42), and major (HR, 1.40; 95% CI, 1.26–1.55) ECG abnormalities compared with controls. Across age-and sex-specific subgroups, SMI patients with ECG abnormalities but no CVD at baseline had highest standardized 10-year absolute risks of fatal CVD. CONCLUSIONS: ECG abnormalities conferred a poorer prognosis among patients with SMI compared with controls without mental illness. SMI patients with ECG abnormalities but no CVD represent a high-risk population that may benefit from greater surveillance and risk management
Thyroid dysfunction and electrocardiographic changes in subjects without arrhythmias:a cross-sectional study of primary healthcare subjects from Copenhagen
ObjectiveThe objective of the present study was to investigate associations of both overt and subclinical thyroid dysfunction with common ECG parameters in a large primary healthcare population.DesignCross-sectional study.Setting and participantsThe study population comprised of primary healthcare patients in Copenhagen, Denmark, who had a thyroid function test and an ECG recorded within 7 days of each other between 2001 and 2011.Data sourcesThe Danish National Patient Registry was used to collect information regarding baseline characteristics and important comorbidities.Outcome measure and study groupsCommon ECG parameters were determined using Marquette 12SL software and were compared between the study groups. The study population was divided into five groups based on their thyroid status. Euthyroid subjects served as the reference group in all analyses.ResultsA total of 132 707 patients (age 52±17 years; 50% female) were included. Hyperthyroidism was significantly associated with higher heart rate and prolonged QTc interval with significant interaction with age (p<0.009) and sex (p<0.001). These associations were less pronounced for patients with higher age. Subclinical hyperthyroidism was associated with higher heart rate among females, and a similar trend was observed among males. Hypothyroidism was associated with slower heart rate and shorter QTc but only in women. Moreover, longer P-wave duration, longer PR interval and low voltage were observed in patients with both subclinical and overt hypothyroidism. However, the presence of low voltage was less pronounced with higher age (p=0.001).ConclusionBoth overt and subclinical thyroid disorders were associated with significant changes in important ECG parameters. Age and gender have significant impact on the association of thyroid dysfunction particularly on heart rate and QTc interval
Risk Prediction of Atrial Fibrillation Based on Electrocardiographic Interatrial Block
Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/144584/1/jah33160_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/144584/2/jah33160-sup-0001-SupInfo.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/144584/3/jah33160.pd
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