Car accidents and credit hire agreements

A motorist whose car is damaged by the negligence of another may recover for the loss suffered, but must take reasonable steps to mitigate that loss. Where a replacement car is hired the charges can be recovered, if the car is needed for use and is similar to the damaged vehicle. Real difficulties arise if the motorist hires on credit. The agreement must comply with regulations applicable to credit agreements and constitute an enforceable contract, and, even then, full recovery of the charges is possible only if the motorist is impecunious. In spite of attempts to calm conflict over these matters, credit hire has prompted a flood of litigation that has often confused issues and created difficult distinctions, which, in turn, have increased tensions in the industry and caused bafflement among motorists

Quasars from the 7C Survey - I:sample selection and radio maps

We describe the selection of candidate radio-loud quasars obtained by cross-matching radio source positions from the low-frequency (151 MHz) 7C survey with optical positions from five pairs of EO POSS-I plates scanned with the Cambridge Automatic Plate-measuring Machine (APM). The sky region studied is centred at RA 10 h 28 m, Dec +41 and covers 0.057 sr. We present VLA observations of the quasar candidates, and tabulate various properties derived from the radio maps. We discuss the selection criteria of the resulting `7CQ' sample of radio-loud quasars. The 70 confirmed quasars, and some fraction of the 36 unconfirmed candidates, constitute a filtered sample with the following selection criteria: 151-MHz flux density S151 > 100 mJy; POSS-I E-plate magnitude E approx R < 20; and POSS-I colour (O - E) < 1.8; the effective area of the survey drops significantly below S151 approx 200 mJy. We argue that the colour criterion excludes few if any quasars, but note, on the basis of recent work by Willott et al. (1998b), that the E magnitude limit probably excludes more than 50 per cent of the radio-loud quasars.Comment: Latex, 30 pages. Accepted by MNRA

Beyond Dialogue - An exploration of the Musalaha: Curriculum of Reconciliation model of interfaith dialogue with relevance for the UK context.

Issues concerning the integration of migrant communities into United Kingdom society have once again become the subject of national debate, with the publication of the Casey Review in December 2016. In the aftermath of terrorist incidents in Manchester and London, as well as the 2016 Referendum vote for the United Kingdom to leave to the European Union, the reported rise in racially motivated hate crimes and an increase in both antisemitism and Islamophobia, the necessity of developing healthy relationships between communities is imperative. When considering the question of whether segregation is on the increase or not Cantle and Kaufman conclude that while minority ethnic communities are dispersing there is significantly less mixing with the ‘White British’ communities, who seem to be withdrawing from mixed areas. The need for integration is vital. This research starts with the premise that religion is part of the solution, not a part of the problem. This qualitative research explores ethnographically the process of interfaith dialogue, by participant observation of three different groups over a five-year period, with intense reflection over the last three years. These groups were made up of Muslims and Christians, and Hindus in one group, all of whom had a deep personal faith in their respective religions. Using Salim Munayer’s Musalaha Six-stage Cycle of Reconciliation, which was pioneered in the Israel-Palestine context of 25 years of dialogue practice among Messianic Jews and Palestinian Christians, the research adapts and builds on this model, for use in interfaith dialogue, developing a fresh definition of ‘interfaith dialogue’ and a method of interfaith dialogue appropriate for the UK context. The thesis makes three main contributions to academic knowledge. First, it presents a new definition and fresh approach to interfaith dialogue with relevance for the UK context, which is particularly relevant for devout believers in their respective religions, to stand alongside other models. Second, the results of the research identify a list of fourteen key themes, including identity, faith and reconciliation, which deserve further analysis. The research methods indicated that there are many more issues that, with further analysis, might be profitably explored. Third, that following the six-stage cycle the path to reconciliation, although remaining hard, is nevertheless achievable, especially for those whose faith provides the motivation and drive to engage at depth with the other

d-Amino acid oxidase and serine racemase in human brain: normal distribution and altered expression in schizophrenia

The N-methyl-d-aspartate receptor co-agonist d-serine is synthesized by serine racemase and degraded by d-amino acid oxidase. Both d-serine and its metabolizing enzymes are implicated in N-methyl-d-aspartate receptor hypofunction thought to occur in schizophrenia. We studied d-amino acid oxidase and serine racemase immunohistochemically in several brain regions and compared their immunoreactivity and their mRNA levels in the cerebellum and dorsolateral prefrontal cortex in schizophrenia. d-Amino acid oxidase immunoreactivity was abundant in glia, especially Bergmann glia, of the cerebellum, whereas in prefrontal cortex, hippocampus and substantia nigra, it was predominantly neuronal. Serine racemase was principally glial in all regions examined and demonstrated prominent white matter staining. In schizophrenia, d-amino acid oxidase mRNA was increased in the cerebellum, and as a trend for protein. Serine racemase was increased in schizophrenia in the dorsolateral prefrontal cortex but not in cerebellum, while serine racemase mRNA was unchanged in both regions. Administration of haloperidol to rats did not significantly affect serine racemase or d-amino acid oxidase levels. These findings establish the major cell types wherein serine racemase and d-amino acid oxidase are expressed in human brain and provide some support for aberrant d-serine metabolism in schizophrenia. However, they raise further questions as to the roles of d-amino acid oxidase and serine racemase in both physiological and pathophysiological processes in the brain

Does Infall End Before the Class I Stage?

We have observed HCO+ J=3-2 toward 16 Class I sources and 18 Class 0 sources, many of which were selected from Mardones et al. (1997). Eight sources have profiles significantly skewed to the blue relative to optically thin lines. We suggest six sources as new infall candidates. We find an equal "blue excess" among Class 0 and Class I sources after combining this sample with that of Gregersen et al. (1997). We used a Monte Carlo code to simulate the temporal evolution of line profiles of optically thick lines of HCO+, CS and H2CO in a collapsing cloud and found that HCO+ had the strongest asymmetry at late times. If a blue-peaked line profile implies infall, then the dividing line between the two classes does not trace the end of the infall stage.Comment: 21 pages, 8 figures, accepted by ApJ for April 20, 2000, added acknowledgmen

Radio Jets in Galaxies with Actively Accreting Black Holes: new insights from the SDSS

The majority of nearby radio-loud AGN are found in massive, old elliptical galaxies with weak emission lines. At high redshifts,however, most known radio AGN have strong emission lines. In this paper, we examine a subset of radio AGN with emission lines selected from the Sloan Digital Sky Survey. The probability for a nearby radio AGN to have emission lines is a strongly decreasing function of galaxy mass and an increasing function of radio luminosity above 10^25 W/Hz. Emission line and radio luminosities are correlated, but with large dispersion. At a given radio power, AGN with small black holes have higher [OIII] luminosities (which we interpret as higher accretion rates) than AGN with big black holes. However, if we scale both radio and emission line luminosities by the black hole mass, we find a correlation between normalized radio power and accretion rate in Eddington units that is independent of black hole mass. There is also a clear correlation between normalized radio power and the age of the stellar population in the galaxy. Present-day AGN with the highest normalized radio powers are confined to galaxies with small black holes. High-redshift, high radio-luminosity AGN could be explained if big black holes were similarly active at earlier cosmic epochs. To investigate why only a small fraction of emission line AGN become radio loud, we create matched samples of radio-loud and radio-quiet AGN and compare their host galaxy properties and environments. The main difference lies in their environments; our local density estimates are a factor 2 larger around the radio-loud AGN. We propose a scenario in which radio-loud AGN with emission lines are located in galaxies where accretion of both cold and hot gas can occur simultaneously. (Abridged)Comment: 18 figures, submitted to MNRA

Genetical and comparative genomics of Brassica under altered Ca supply identifies Arabidopsis Ca-transporter orthologs

Although Ca transport in plants is highly complex, the overexpression of vacuolar Ca2+ transporters in crops is a promising new technology to improve dietary Ca supplies through biofortification. Here, we sought to identify novel targets for increasing plant Ca accumulation using genetical and comparative genomics. Expression quantitative trait locus (eQTL) mapping to 1895 cis- and 8015 trans-loci were identified in shoots of an inbred mapping population of Brassica rapa (IMB211 x R500); 23 cis- and 948 trans-eQTLs responded specifically to altered Ca supply. eQTLs were screened for functional significance using a large database of shoot Ca concentration phenotypes of Arabidopsis thaliana. From 31 Arabidopsis gene identifiers tagged to robust shoot Ca concentration phenotypes, 21 mapped to 27 B. rapa eQTLs, including orthologs of the Ca2+ transporters At-CAX1 and At-ACA8. Two of three independent missense mutants of BraA.cax1a, isolated previously by targeting induced local lesions in genomes, have allele-specific shoot Ca concentration phenotypes compared with their segregating wild types. BraA.CAX1a is a promising target for altering the Ca composition of Brassica, consistent with prior knowledge from Arabidopsis. We conclude that multiple-environment eQTL analysis of complex crop genomes combined with comparative genomics is a powerful technique for novel gene identification/prioritization

A First Attempt to Bring Computational Biology into Advanced High School Biology Classrooms

Computer science has become ubiquitous in many areas of biological research, yet most high school and even college students are unaware of this. As a result, many college biology majors graduate without adequate computational skills for contemporary fields of biology. The absence of a computational element in secondary school biology classrooms is of growing concern to the computational biology community and biology teachers who would like to acquaint their students with updated approaches in the discipline. We present a first attempt to correct this absence by introducing a computational biology element to teach genetic evolution into advanced biology classes in two local high schools. Our primary goal was to show students how computation is used in biology and why a basic understanding of computation is necessary for research in many fields of biology. This curriculum is intended to be taught by a computational biologist who has worked with a high school advanced biology teacher to adapt the unit for his/her classroom, but a motivated high school teacher comfortable with mathematics and computing may be able to teach this alone. In this paper, we present our curriculum, which takes into consideration the constraints of the required curriculum, and discuss our experiences teaching it. We describe the successes and challenges we encountered while bringing this unit to high school students, discuss how we addressed these challenges, and make suggestions for future versions of this curriculum.We believe that our curriculum can be a valuable seed for further development of computational activities aimed at high school biology students. Further, our experiences may be of value to others teaching computational biology at this level. Our curriculum can be obtained at http://ecsite.cs.colorado.edu/?page_id=149#biology or by contacting the authors