2 research outputs found
The efficacy of submucosal tramadol in the postoperative treatment of pain following septoplasty operations
Tramadol is a centrally acting opioid which is
effective for moderate-severe pain and is being used for
various acute and chronic pain scenarios. The primary endpoint
of this controlled, randomized double blind study was
to evaluate the effect of submucosal tramadol on VAS scores
after septoplasty operations and secondary endpoint was to
investigate the effects on total opioid and additional analgesic
consumption and patient satisfaction. 60 patients
scheduled for septoplasty under general anaesthesia were
enrolled. In Group T, at the end of surgery following
hemostasis, 2 mg/kg tramadol was applied as submucosal
infiltration to both surgical sites, 2 ml (total 4 ml), by the
surgeon. In Group P, at the end of surgery following
hemostasis, 2 ml isotonic solution (total 4 ml) was applied as
submucosal infiltration to both surgical sites by the surgeon.
Total opioid consumption, VAS scores, patient satisfaction
was evaluated at the end of 24 h VAS values were higher in
Group P on the first and second postoperative hours. Patient
controlled analgesia demand and delivery values were higher
in Group P on the postoperative 1, 2, 4, 6, 12 and 24th hours.
Patient satisfaction was higher and opioid consumption was
lower in Group T compared to Group P. There was no difference
in additional analgesic consumption between two
groups.The results show that patients receiving tramadol had
lower VAS scores compared with the placebo groups
postoperatively