Research into Dry Turning of Welded Surface by Replaceable Cutting Insert with Closed Loop Heat Removal

A special tool has been devised incorporating a closed loop system based on Peltier thermoelectric couples to cool replaceable hard alloy inserts. Experimental research has been done into dry turning of a X20Cr13 steel welded surface with a SECO cubic boron nitride circular plate at the cutting speed increasing from 100 to 300 m/min. It has been determined that Ra surface roughness decreases by 22% while Rz surface roughness goes down by 26%; in addition, the wear flat of tool tips diminishes by 17%. © 2018 Published under licence by IOP Publishing Ltd.The work was supported by Ministry of Education and Science of the Russian Federation, contract № 02.G25.31.0148 with Sverdlovsk Instrumental Plant within the framework of Research and Development Project No Н979.210.007/15, July 28, 2015 for the federal autonomous educational institution of higher education “Ural Federal University”

Синтез новых building blocks на основе вердазильных радикалов

Метод модификации органических каркасов спин-содержащими строительными блокамипредлагается перспективной альтернативой классическому многостадийному синтезу радикальныхфрагментов непосредственно на органическом каркасе. Одной из наиболее удобных реакций длямодификации молекул может выступать палладий-катализируемые реакции кросс-сочетания.Полученные вердазильные радикалы, имеющие галогенированные заместители, благодаря своей высокойстабильности являются оптимальными для одностадийной модификации. Стабильные радикалы собъёмными сопряженными заместителями в положениях 2 и 4 были синтезированы из 1,3,5-замещённых формазанов, полученных по реакции гидразонов с арендиазоний тозилатами - новымклассом стабильных диазониевых солей

A mathematical model of the layered plate throwing by detonation products

The problem of the layered plates throwing in the conditions of incomplete dispersal of detonation products (DP) is devoted to quite a lot of work, but this problem is usually solved either by various numerical methods, which in practice are not applicable due to the significant difficulties for calculations, or in one-dimensional form, that does not allows for the correct determination of pressure in DP and turn angles after the impact of the plates. This paper provides a mathematical model of multi-layered throwing calculation using fairly simple analytical equations to determine the above parameters when solving various applications for explosive processing of materials by a sliding detonation wave. © 2021 Author(s).The research was supported by Ministry of Science and Higher Education of the Russian Federation, state contract № 075-03-2020-582/4 and by Russian Foundation for Basic Research, project no. 20-08-00-00873

The termal deformation reducing in sheet metal at manufacturing parts by CNC cutting machines

In various industries for the manufacturing of parts (workpieces) from sheet metal the CNC machines for thermal cutting (laser/plasma/gas cutting) are used. During process of thermal cutting, various deformations of the metal can occur, that cause the distortion of the geometric forms and sizes of the cut parts. These distortions are caused both by the uneven distribution of temperature in the sheet, and by certain geometric characteristics of the cutting process. Geometric characteristics are determined by the set sequence (order) of cutting of figured parts, as well as by selecting the piercing points of sheet material, i.e. the places of inserting the tool into the material. Previously, the authors formulated heuristic geometric rules, that allow reducing the value of geometric deformations of parts produced by the CNC cutting machines. To comply with these rules, users of Computer-Aided Design (CAM) systems that are used to generate NC programs, have to use interactive design methods. One of these rules (so-called "Part Hardness Rule") refers to the selecting the location of points for inserting (piercing) a CNC machine tool into the material. The paper describes a model based on the use of the heat conduction equation, which makes it possible to calculate the temperature of the sheet material at each moment of cutting process. The computational experiments showed that the points, which according to the "Part Hardness Rule" can't be used for piercing, have a higher material temperature than the points that satisfy this rule. In the paper the results of the computational experiments are given. Another rule (socalled "Sheet Hardness Rule"), which also reduces the deformation of the material during thermal cutting, refers to the order of parts cutting from the sheet. A heuristic algorithm that automatically generates the order of cutting parts that satisfy the rules of "Part Hardness" and of "Sheet Hardness" is developed. Developed software allows us to abandon the interactive methods of the NC programs generation for the thermal cutting of figured parts on CNC machines. © 2019 IOP Publishing Ltd. All rights reserved.Russian Foundation for Basic Research, RFBRThe work was supported by the Russian Foundation for Basic Research (grant 19-01-00573)

Nanodiamonds as Carriers for Address Delivery of Biologically Active Substances

Surface of detonation nanodiamonds was functionalized for the covalent attachment of immunoglobulin, and simultaneously bovine serum albumin and Rabbit Anti-Mouse Antibody. The nanodiamond-IgGI125 and RAM-nanodiamond-BSAI125 complexes are stable in blood serum and the immobilized proteins retain their biological activity. It was shown that the RAM-nanodiamond-BSAI125 complex is able to bind to the target antigen immobilized on the Sepharose 6B matrix through antibody–antigen interaction. The idea can be extended to use nanodiamonds as carriers for delivery of bioactive substances (i.e., drugs) to various targets in vivo