422 research outputs found
Labour supply and skills demands in fashion retailing
If, as Adam Smith once famously suggested, Britain was a nation of shopkeepers then it is now a nation of shopworkers. Retail is now a significant part of the UK economy, accounting for ÂŁ256 billion in sales and one-third of all consumer spending (Skillsmart, 2007). It is the largest private sector employer in the UK, employing 3m workers, or 1 in 10 of the working population. For future job creation in the UK economy retail is also similarly prominent and the sector is expected to create a further 250,000 jobs to 2014 (Skillsmart, 2007). The centrality of retail to economic success and job creation is apparent in other advanced economies. For example, within the US, retail sales is the occupation with the largest projected job growth in the period 2004-2014 (Gatta et al., 2009) and in Australia retail accounts for 1 in 6 workers (Buchanan et al., 2003). Within the UK these workers are employed in approximately 290,000 businesses, encompassing large and small organizations and also a number of sub-sectors. This variance suggests that retail should not be regarded as homogenous in its labour demands. Hart et al. (2007) note how skill requirements and the types of workers employed may differ across the sector. This chapter further opens up this point, providing an analysis of the labour supply and skills demands for the sub-sectors of clothing, footwear and leather goods, which are described by Skillsmart (2007: 48) as being 'significant categories in UK retailing'
Symmetry superposition studied by surface second-harmonic generation.
The components of a third-rank Ï(2) tensor have been split into contributions due to 1-fold, 2-fold, 3-fold, and â-fold or isotropic rotation axes for a surface of Cs symmetry. Theoretical analysis of the rotation patterns obtained by the surface second-harmonic (SH) generation indicates that a complete symmetry analysis cannot be performed without knowledge of the relevant distribution functions. Rotation axes of lower symmetry create via ââovertonesââ or ââharmonicsââ contributions apparent in the analysis of the rotation axes of higher symmetry. An experimental example is the observation of structural changes of Au(111) surfaces in an aqueous electrolytic environment. Potential-dependent buildup and removal of a Au(111)-(1Ă23) surface could be monitored in situ and in real time. Symmetry analysis of the SH rotation patterns reveals both contributions due to a 3-fold axis due to the regular (1Ă1) structure and simultaneously a 1-fold and a 2-fold axis due to the (1Ă23) reconstruction
The New âHidden Abodeâ: Reflections on Value and Labour in the New Economy
In a pivotal section of Capital, volume 1, Marx (1976: 279) notes that, in order to understand the capitalist production of value, we must descend into the âhidden abode of productionâ: the site of the labour process conducted within an employment relationship. In this paper we argue that by remaining wedded to an analysis of labour that is confined to the employment relationship, Labour Process Theory (LPT) has missed a fundamental shift in the location of value production in contemporary capitalism. We examine this shift through the work of Autonomist Marxists like Hardt and Negri, Lazaratto and Arvidsson, who offer theoretical leverage to prize open a new âhidden abodeâ outside employment, for example in the âproduction of organizationâ and in consumption. Although they can open up this new âhidden abodeâ, without LPT's fine-grained analysis of control/resistance, indeterminacy and structured antagonism, these theorists risk succumbing to empirically naive claims about the ânew economyâ. Through developing an expanded conception of a ânew hidden abodeâ of production, the paper demarcates an analytical space in which both LPT and Autonomist Marxism can expand and develop their understanding of labour and value production in today's economy. </jats:p
Role of osmolality in blood pressure stability after dialysis and ultrafiltration
Role of osmolality in blood pressure stability after dialysis and ultrafiltration. To clarify the mechanisms involved in the stability of blood pressure during ultrafiltration (UF) alone versus regular dialysis, this study systematically examined the importance of changes in serum potassium, osmolality, and plasma norepinephrine during several dialysis maneuvers. Six stable, normotensive chronic dialysis patients were subjected to a uniform 2 to 3% decrease in body weight during the 2 hours of each dialysis maneuver. Supine to upright mean blood pressure (MBP) decreased (90 to 75 mm Hg, P < 0.05), and three patients became symptomatic after weight loss during regular dialysis, but orthostatic blood pressure was stable (89 to 86 mm Hg, NS) and the patients were asymptomatic after UF and weight loss. Isokalemic regular dialysis did not afford hemodynamic stability, as orthostatic MBP declined (85 to 56 mm Hg, P < 0.02), and four of the patients again were symptomatic after standing. A continuous hypertonic mannitol (25%) infusion during the 2-hour dialysis, however, kept osmolality from decreasing and was associated with a stable orthostatic MBP (89 to 83 mm Hg, NS). A continuous infusion of isotonic mannitol (5%) given in a volume five times that of the hypertonic mannitol failed to prevent orthostatic hypotension (89 to 60 mm Hg, P < 0.005). Plasma norepinephrine concentrations were high in these patients and increased only modestly after weight loss. These results implicate constant plasma osmolality as a critical protective factor of blood pressure during UF and further demonstrate that changes in blood pressure may be dissociated from changes in both serum potassium and plasma norepinephrine concentration.RĂŽle de l'osmolalitĂ© dans la stabilitĂ© de la pression artĂ©rielle aprĂšs dialyse et ultrafiltration. Afin de clarifier les mĂ©canismes impliquĂ©s dans la stabilitĂ© de la pression artĂ©rielle au cours de l'ultrafiltration (UF) seule par comparaison avec la dialyse habituelle ce travail Ă©value systĂ©matiquement l'importance des modifications de la kaliĂ©mie, de l'osmolalitĂ© et de la norĂ©pinĂ©phrine plasmatique au cours de plusieurs tactiques de dialyse. Six sujets stables, normotendus, en hĂ©modialyse chronique ont subi une diminution de poids corporel de 2 Ă 3% au cours des 2 heures de chaque tactique de dialyse. La pression artĂ©rielle moyenne a diminuĂ© de la position couchĂ©e Ă la position debout (de 90 Ă 75 mm Hg, P < 0,05) et trois patients sont devenus symptomatiques aprĂšs la perte de poids au cours de la dialyse habituelle. Par contre la pression artĂ©rielle orthostatique a Ă©tĂ© stable (89 Ă 86 mm Hg, NS) et les malades ont Ă©tĂ© asymptomatiques aprĂšs UF. La dialyse habituelle isokaliĂ©mique n'a pas dĂ©terminĂ© de stabilitĂ© hĂ©modynamique, la pression artĂ©rielle moyenne orthostatique a diminuĂ© (85 Ă 56 mm Hg, P < 0,02) et quatre malades ont Ă©tĂ© Ă nouveau symptomatiques quand ils se sont levĂ©s. Cependant quand une perfusion continue de mannitol hypertonique (25%) pendant les deux heures de la dialyse a empĂȘchĂ© la baisse de l'osmolalitĂ© la pression artĂ©rielle moyenne orthostatique a Ă©tĂ© stable (89 Ă 83 mm Hg, NS). Une perfusion continue de mannitol isotonique (5%) apportant un volume cinq fois celui du mannitol hypertonique n'a pas empĂȘchĂ© l'hypotention orthostatique (89 Ă 60 mm Hg, P < 0,005). Les concentrations plasmatiques de norĂ©pinĂ©phrine Ă©taient Ă©levĂ©es chez ces malades et n'ont que peu augmentĂ© aprĂšs la perte de poids. Ces rĂ©sultats impliquent qu'une osmolalitĂ© plasmatique constante est un facteur protecteur critique pour la pression artĂ©rielle au cours de UF et ils dĂ©montrent, de plus, que les modifications de la pression artĂ©rielle peuvent ĂȘtre dissociĂ©es des modifications du potassium plasmatique et de la concentration de norĂ©pinĂ©phrine
Impact of cyclooxygenase inhibitors in the Women's Health Initiative hormone trials: secondary analysis of a randomized trial.
OBJECTIVES: We evaluated the hypothesis that cyclooxygenase (COX) inhibitor use might have counteracted a beneficial effect of postmenopausal hormone therapy, and account for the absence of cardioprotection in the Women's Health Initiative hormone trials. Estrogen increases COX expression, and inhibitors of COX such as nonsteroidal anti-inflammatory agents appear to increase coronary risk, raising the possibility of a clinically important interaction in the trials. DESIGN: The hormone trials were randomized, double-blind, and placebo-controlled. Use of nonsteroidal anti-inflammatory drugs was assessed at baseline and at years 1, 3, and 6. SETTING: The Women's Health Initiative hormone trials were conducted at 40 clinical sites in the United States. PARTICIPANTS: The trials enrolled 27,347 postmenopausal women, aged 50-79 y. INTERVENTIONS: We randomized 16,608 women with intact uterus to conjugated estrogens 0.625 mg with medroxyprogesterone acetate 2.5 mg daily or to placebo, and 10,739 women with prior hysterectomy to conjugated estrogens 0.625 mg daily or placebo. OUTCOME MEASURES: Myocardial infarction, coronary death, and coronary revascularization were ascertained during 5.6 y of follow-up in the estrogen plus progestin trial and 6.8 y of follow-up in the estrogen alone trial. RESULTS: Hazard ratios with 95% confidence intervals were calculated from Cox proportional hazard models stratified by COX inhibitor use. The hazard ratio for myocardial infarction/coronary death with estrogen plus progestin was 1.13 (95% confidence interval 0.68-1.89) among non-users of COX inhibitors, and 1.35 (95% confidence interval 0.86-2.10) among continuous users. The hazard ratio with estrogen alone was 0.92 (95% confidence interval 0.57-1.48) among non-users of COX inhibitors, and 1.08 (95% confidence interval 0.69-1.70) among continuous users. In a second analytic approach, hazard ratios were calculated from Cox models that included hormone trial assignment as well as a time-dependent covariate for medication use, and an interaction term. No significant interaction was identified. CONCLUSIONS: Use of COX inhibitors did not significantly affect the Women's Health Initiative hormone trial results
Scoping Potential Routes to UK Civil Unrest via the Food System: Results of a Structured Expert Elicitation
We report the results of a structured expert elicitation to identify the most likely types of potential food system disruption scenarios for the UK, focusing on routes to civil unrest. We take a backcasting approach by defining as an end-point a societal event in which 1 in 2000 people have been injured in the UK, which 40% of experts rated as âPossible (20â50%)â, âMore likely than not (50â80%)â or âVery likely (>80%)â over the coming decade. Over a timeframe of 50 years, this increased to 80% of experts. The experts considered two food system scenarios and ranked their plausibility of contributing to the given societal scenario. For a timescale of 10 years, the majority identified a food distribution problem as the most likely. Over a timescale of 50 years, the experts were more evenly split between the two scenarios, but over half thought the most likely route to civil unrest would be a lack of total food in the UK. However, the experts stressed that the various causes of food system disruption are interconnected and can create cascading risks, highlighting the importance of a systems approach. We encourage food system stakeholders to use these results in their risk planning and recommend future work to support prevention, preparedness, response and recovery planning
An in situ study of reconstructed gold electrode surfaces by second harmonic generation.
Second harmonic generation (SHG) was employed to monitor in situ the potential-induced reconstruction of Au(111) and Au(100) electrodes. Rotating the sample by 360° about the surface normal yields for the unreconstructed Au(111)-(1Ă1) surface the well-known threefold symmetry pattern in the SHG intensity, while Au(100)-(1Ă1) shows no rotational anisotropy, as expected for C4v symmetry. For the reconstructed Au(111)-(1Ă23) surface, however, an additional onefold symmetry pattern is observed, which allows in situ monitoring of the structural transition between (1Ă1) and (1Ă23). For the reconstructed Au(100)-(5Ă20) surface, a threefold symmetry pattern was found
Sub-surface Oxygen and Surface Oxide Formation at Ag(111): A Density-functional Theory Investigation
To help provide insight into the remarkable catalytic behavior of the
oxygen/silver system for heterogeneous oxidation reactions, purely sub-surface
oxygen, and structures involving both on-surface and sub-surface oxygen, as
well as oxide-like structures at the Ag(111) surface have been studied for a
wide range of coverages and adsorption sites using density-functional theory.
Adsorption on the surface in fcc sites is energetically favorable for low
coverages, while for higher coverage a thin surface-oxide structure is
energetically favorable. This structure has been proposed to correspond to the
experimentally observed (4x4) phase. With increasing O concentrations, thicker
oxide-like structures resembling compressed Ag2O(111) surfaces are
energetically favored. Due to the relatively low thermal stability of these
structures, and the very low sticking probability of O2 at Ag(111), their
formation and observation may require the use of atomic oxygen (or ozone, O3)
and low temperatures. We also investigate diffusion of O into the sub-surface
region at low coverage (0.11 ML), and the effect of surface Ag vacancies in the
adsorption of atomic oxygen and ozone-like species. The present studies,
together with our earlier investigations of on-surface and
surface-substitutional adsorption, provide a comprehensive picture of the
behavior and chemical nature of the interaction of oxygen and Ag(111), as well
as of the initial stages of oxide formation.Comment: 17 pages including 14 figures, Related publications can be found at
http://www.fhi-berlin.mpg.de/th/paper.htm
The CABI Trial: an Unblinded Parallel Group Randomised Controlled Feasibility Trial of Long-Course Antibiotic Therapy (28 Days) Compared with Short Course (â€â10 Days) in the Prevention of Relapse in Adults Treated for Complicated Intra-Abdominal Infection
Purpose
Relapse after complicated intra-abdominal infection (cIAI) remains common after treatment. The optimal antibiotic treatment duration for cIAIs is uncertain, especially in cases where source control is not achieved. We hypothesised that in patients with cIAIs, regardless of source control intervention, there would be a lower relapse rate with long-course antibiotics (28 days) compared with short course (â€â10 days). We piloted a trial comparing â€â10-day with 28-day antibiotic treatment for cIAI.
Methods
A randomised controlled unblinded feasibility trial was conducted. Eligible participants were adult patients with a cIAI that were diagnosed â€â6 days prior to screening. Randomisation was to long-course (28 days) or short-course (â€10 days) antibiotic therapy. Choice of antibiotics was determined by the clinical team. Participants were followed up for 90 days. Primary outcomes were willingness of participants to be randomised and feasibility of trial procedures.
Results
In total, 172 patients were screened, 84/172 (48.8%) were eligible, and 31/84 (36.9%) were randomised. Patients were assigned to either the short-course arm (18/31, 58.0%) or the long-course arm (13/31, 41.9%). One patient in the short-course arm withdrew after randomisation. In the short-course arm, 4/17 (23.5%) were treated for a cIAI relapse vs 0/13 (0.0%) relapses in the long-course arm. Protocol violations included deviations from protocol-assigned antibiotic duration and interruptions to antibiotic therapy.
Conclusions
This feasibility study identified opportunities to increase recruitment in a full trial. This study demonstrates completion of a randomised controlled trial to further evaluate if the optimum antibiotic duration for cIAIs is feasible
âGet yourself some nice, neat, matching box filesâ: research administrators and occupational identity work
To date, qualitative research into occupational groups and cultures within academia has been relatively scarce, with an almost exclusive concentration upon teaching staff within universities and colleges. This article seeks to address this lacuna and applies the interactionist concept of âidentity workâ in order to examine one specific group to date under-researched: graduate research administrators.
This occupational group is of sociological interest as many of its members appear to span the putative divide between âacademicâ and âadministrativeâ occupational worlds within higher education. An exploratory, qualitative research project was undertaken, based upon interviews with
27 research administrators. The study analyses how research administrators utilise various forms of identity work to sustain credible occupational identities, often in the face of considerable challenge from their academic colleagues
- âŠ