The Role of Oxidative Stress in Alzheimer\u27s Disease

Over four million individuals in the United States currently suffer from Alzheimer\u27s disease (AD), a devastating disorder of progressive dementia. Within the next several decades, AD is expected to affect over 22 million people globally. AD can only be definitively diagnosed by postmortem examination. Thus, investigation into the specific pathogenesis of neuronal degeneration and death in AD on a biochemical level is essential for both earlier diagnosis and potential treatment and prevention options. Overproduction of amyloid [3-peptide (A[3) in the brain leads to both free radical oxidative stress and toxicity to neurons in AD. My undergraduate biochemical studies with regard to AD explore the various ways in which free radical oxidative stress might contribute to the pathology of AD. In particular, this review highlights studies using Af3-precursor mutations in animal models, and analysis of histone-DNA interactions

The Positive Impacts of a Professional Learning Community Model on Student Achievement in Small Schools

This study explores the impact of professional learning communities on student achievement in a small school setting. Aaron Hansen’s book, How to Develop PLCs for Singletons and Small Schools, offered a guide for arranging vertical, grade-level teams with one teacher per grade level at one private, K-8 school. The faculty engaged in high quality, effective professional development using PLC objectives and norms to analyze NWEA MAP data. They adapted instructional practices and implemented formative assessments to influence student growth in math and reading scores. Results indicate that the PLC training that took place between the Fall and Winter MAP testing cycles positively impacted student growth results from Winter to Spring tests. Research limitations are addressed in the discussion section

The Positive Impacts of a Professional Learning Community Model on Student Achievement in Small Schools

This study explores the impact of professional learning communities on student achievement in a small school setting. Aaron Hansen’s book, How to Develop PLCs for Singletons and Small Schools, offered a guide for arranging vertical, grade-level teams with one teacher per grade level at one private, K-8 school. The faculty engaged in high quality, effective professional development using PLC objectives and norms to analyze NEWA MAP data. They adapted instructional practices and implemented formative assessments to influence student growth in math and reading scores. Results indicate that the PLC training that took place between the Fall and Winter MAP testing cycles positively impacted student growth results from Winter to Spring tests. Research limitations are addressed in the discussion section

A Systematic Review of the Impact of Focused Trauma Education in Low-resource

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Exploring the Significance of Bidirectional Learning for Global Health Education

The value of bidirectional learning is emphasized both in global health and local community engagement. Conceptualizations of bidirectional learning for global health education are discussed, including implications when it is defined as mutual learning, codevelopment, or academic partnerships. Additionally, we review the relationship of bidirectional learning to different learning theories. Case studies from the field offer examples of how bidirectional learning can occur in the classroom, through academic partnerships, or both. Finally, recommendations are offered to facilitate bidirectional learning in global health education, including in identifying challenges faced by educators in lower-resourced settings who wish to offer bidirectional learning to their students through partnership with higher-resourced academic institutions

Should the development of orthopaedic trauma nursing be a priority in low to middle income countries? A scoping review

Background: Traumatic orthopaedic injuries are responsible for 5.8 million deaths every year, with 90% occurring in Low to Middle Income Countries. Approximately six times as many people are injured due to trauma than those who die of it. Nursing is an under-utilised resource in global trauma care and little research exists into the availability or training of skilled orthopaedic nurses in Low to Middle Income Countries. Objectives: This scoping review aims to summarise and critique the existing body of research to identify if the development. And in some cases, establishment, of trauma and orthopaedic nursing should be a priority in low resource settings. The review also aims to identify any barriers to the advancement of the speciality, and any existing solutions to support nurses training and development. Methodology: A scoping literature search was conducted, searching four databases (ProQuest, Medline, CINHAL and SOLAR) with key words and phrases to identify current literature. Results: Eleven papers were identified. Key themes include the need to prioritise nursing education in Low to Middle Income Countries and upskill and utilise the nursing workforce to provide care to trauma patients. Conclusions: Significant investment in the development of orthopaedic nursing is needed in Low to Middle Income Countries to reduce morbidity and mortality and retain the local nursing workforce