2,278 research outputs found
Confinement and Condensates Without Fine Tuning in Supergravity Duals of Gauge Theories
We discuss a solution of the equations of motion of five-dimensional gauged
type IIB supergravity that describes confining SU(N) gauge theories at large N
and large 't Hooft parameter. We prove confinement by computing the Wilson
loop, and we show that our solution is generic, independent of most of the
details of the theory. In particular, the Einstein-frame metric near its
singularity, and the condensates of scalar, composite operators are universal.
Also universal is the discreteness of the glueball mass spectrum and the
existence of a mass gap. The metric is also identical to a generically
confining solution recently found in type 0B theory.Comment: 19 pages, Late
Novel Local CFT and Exact Results on Perturbations of N=4 Super Yang Mills from AdS Dynamics
We find new, local, non-supersymmetric conformal field theories obtained by
relevant deformations of the N=4 super Yang Mills theory in the large
limit. We contruct interpolating supergravity solutions that naturally
represent the flow from the N=4 super Yang Mills UV theory to these
non-supersymmetric IR fixed points. We also study the linearization around the
N=4 superconformal point of N=1 supersymmetric, marginal deformations. We show
that they give rise to N=1 superconformal fixed points, as expected from
field-theoretical arguments.Comment: Version accepted by JHE
Stable determination of sound-hard polyhedral scatterers by a minimal number of scattering measurements
The aim of the paper is to establish optimal stability estimates for the determination of sound-hard polyhedral scatterers by a minimal number of far-field measurements. This work is a significant and highly nontrivial extension of the stability estimates for the determination of sound-soft polyhedral scatterers by far-field measurements, proved by one of the authors, to the much more challenging sound-hard case.
The admissible polyhedral scatterers satisfy minimal apriori assumptions of Lipschitz type and may include at the same time solid obstacles and screen-type components. In this case we obtain a stability estimate with N far-field measurements, N being the space dimension. Important features of such an estimate are that we have an explicit dependence on the parameter h representing the minimal size of the cells forming the boundaries of the admissible polyhedral scatterers, and that the modulus of continuity, provided the error is small enough with respect to h, does not depend on h. If we restrict to N=2,3 and to polyhedral obstacles, that is to polyhedra, then we obtain stability estimates with fewer measurements, namely first with N-1 measurements and then with a single measurement. In this case the dependence on h is not explicit anymore and the modulus of continuity depends on h as well
Sensory-motor brain dynamics reflect architectural affordances
Anticipating meaningful actions in the environment is an essential function of the brain. Such predictive mechanisms originate from the motor system and allow for inferring actions from environmental affordances, the potential to act within a specific environment. Using architecture, we provide a unique perspective to the abiding debate in cognitive neuroscience and philosophy on whether cognition depends on movement or is decoupled from our physical structure. To investigate cognitive processes associated with architectural affordances, we used a Mobile Brain/Body Imaging approach recording brain activity synchronized to head-mounted virtual reality. Participants perceived and acted upon virtual transitions ranging from non-passable to easily passable. We demonstrate that early sensory brain activity, upon revealing the environment and before actual movement, differed as a function of affordances. Additionally, movement through transitions was preceded by a motor-related negative component also depended on affordances. Our results suggest that potential actions afforded by an environment influence perception
Nebivolol: haemodynamic effects and clinical significance of combined beta-blockade and nitric oxide release.
Nebivolol is a third-generation beta-adrenergic receptor antagonist (beta-blocker) with high selectivity for beta(1)-adrenergic receptors. In addition, it causes vasodilatation via interaction with the endothelial L-arginine/nitric oxide (NO) pathway. This dual mechanism of action underlies many of the haemodynamic properties of nebivolol, which include reductions in heart rate and blood pressure (BP), and improvements in systolic and diastolic function. With respect to BP lowering, the NO-mediated effects cause a reduction in peripheral vascular resistance and an increase in stroke volume with preservation of cardiac output. Flow-mediated dilatation and coronary flow reserve are also increased during nebivolol administration. Other haemodynamic effects include beneficial effects on pulmonary artery pressure, pulmonary wedge pressure, exercise capacity and left ventricular ejection fraction. In addition, nebivolol does not appear to have adverse effects on lipid metabolism and insulin sensitivity like traditional beta-blockers. The documented beneficial haemodynamic effects of nebivolol are translated into improved clinical outcomes in patients with hypertension or heart failure. In patients with hypertension, the incidence of bradycardia with nebivolol is often lower than that with other currently available beta-blockers. This, along with peripheral vasodilatation and NO-induced benefits such as antioxidant activity and reversal of endothelial dysfunction, should facilitate better protection from cardiovascular events. In addition, nebivolol has shown an improved tolerability profile, particularly with respect to events commonly associated with beta-blockers, such as fatigue and sexual dysfunction. Data from SENIORS (Study of the Effects of Nebivolol Intervention on Outcomes and Rehospitalization in Seniors with Heart Failure) showed that significantly fewer nebivolol versus placebo recipients experienced the primary endpoint of all-cause mortality or cardiovascular hospitalization. The benefits of nebivolol therapy were shown to be cost effective. Thus, nebivolol is an effective and well tolerated agent with benefits over and above those of traditional beta-blockade because of its effects on NO release, which give it unique haemodynamic effects, cardioprotective activity and a good tolerability profile
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