50 research outputs found

    Prevalence of Antibodies Against Virus-Like Particles of Epidermodysplasia Verruciformis-Associated HPV8 in Patients at Risk of Skin Cancer

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    There is increasing evidence for widespread occurrences of infection with Epidermodysplasia verruciformis-related human papillomaviruses, both in the general population and in immunosuppressed patients. In order to test for the prevalence of antibodies directed against the native L1 epitopes exposed on the surface of the virions, we have established an IgG-specific enzyme-linked immunosorbent assay with L1 virus-like particles of the Epidermodysplasia verruciformis-specific human papillomavirus 8 as antigen to screen 567 representative serum samples from the general population and immunosuppressed/dermatologic patients. Among healthy European donors (n = 210), 7.6% were found to be seropositive. In a group of renal transplant recipients (n = 185) the antibody prevalence was elevated to 21.1%, irrespective of the presence or absence of skin cancer. High positivity rates could be detected among (i) immunocompetent patients with nonmelanoma skin tumors (45.6%, n = 79) and (ii) Psoralene/UVA treated psoriasis patients (42.9%, n = 42). In contrast, anti-human papillomavirus 8-virus-like particle antibodies were found in only 6.8% of Hodgkin lymphoma patients (n = 44)

    Measurement of Lambda and Anti-Lambda particles in Au plus Au collisions at root s(NN)=130 GeV

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    We present results on the measurement of Lambda and Anti-Lambda production in Au+Au collisions at root s(NN)=130 GeV with the PHENIX detector at the Relativistic Heavy Ion Collider. The transverse momentum spectra were measured for minimum bias and for the 5% most central events. The Anti-Lambda/Lambda ratios are constant as a function of p(T) and the number of participants. The measured net Lambda density is significantly larger than predicted by models based on hadronic strings (e.g., HIJING) but in approximate agreement with models which include the gluon-junction mechanism

    Single identified hadron spectra from root s(NN)=130 GeV Au+Au collisions

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    Transverse momentum spectra and yields of hadrons are measured by the PHENIX collaboration in Au+Au collisions at roots(NN)=130 GeV at the Relativistic Heavy Ion Collider. The time-of-flight resolution allows identification of pions to transverse momenta of 2 GeV/c and protons and antiprotons to 4 GeV/c. The yield of pions rises approximately linearly with the number of nucleons participating in the collision, while the number of kaons, protons, and antiprotons increases more rapidly. The shape of the momentum distribution changes between peripheral and central collisions. Simultaneous analysis of all the p(T) spectra indicates radial collective expansion, consistent with predictions of hydrodynamic models. Hydrodynamic analysis of the spectra shows that the expansion velocity increases with collision centrality and collision energy. This expansion boosts the particle momenta, causing the yield from soft processes to exceed that for hard to large transverse momentum, perhaps as large as 3 GeV/c

    Overview of PHENIX results from the first RHIC run

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    Results from the PHENIX experiment for the first RHIC run with Au-Au collisions at roots(NN) = 130 GeV are presented. The systematic variation with centrality of charged particle multiplicity, transverse energy, elliptic flow, identified particle spectra and yield ratios, and production of charged particles and pi(0)\u27s at high transverse momenta are presented. Results on two-pion correlations and electron spectra are also provided, along with a discussion of plans for the second run at RHIC

    A rare case of extradural lumbar nerve root cavernoma

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    We present a very rare case of an extradural nerve root cavernoma of the lumbar spine. The patient had signs of radiculopathy for the last 3 years. Conservative treatment was unsuccessful. The MRI-image revealed a lesion mimicking neurinoma of the left L3 nerve root. Surgical removal of the lesion was performed by an extreme lateral transmuscular approach. Intraoperatively, the lesion showed signs of intratumoural bleeding. In the histological analysis, a cavernoma of the nerve root was established. Despite the benign nature of these very rare lesions, complete surgical removal should be performed since a spontaneous regression is not to be expected and surgery relieves the patients from their symptoms
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