Inauguration Remarks of John J. Petillo, Ph.D.

Remarks of John J. Petillo, Ph.D. September 21, 2011 in the Chapel of the Holy Spirit on the occasion of his inauguration as President of Sacred Heart University. A Time for New Beginnings

Respecting Differences is a Non-negotiable, Moral Imperative

Fear and ignorance are blissful companions when it comes to intolerance. It assumes innumerable forms. Sometimes it is blatant and obvious. But oftentimes its posture is ambiguous, disingenuous or lacking overt hostility

60th Anniversary of SHU Announcement

Email sent to the Sacred Heart community announcing the 60th anniversary of the founding of the Catholic university

Thinking of and Praying for the Population in India

Today I want to reach out to the Indian members of our community

Memorial Service Thank You

Today was both a moving and heartbreaking day at Sacred Heart as we honored those in the state who have been lost to COVID-19, along with those connected to members of our community, by reading their names. One of the University’s core values is to recognize the worth and dignity of every human being, and that is what we did today by putting names—and in some cases, faces—to the more than 7,000 people in this state who have already succumbed to this deadly disease. Recording of the Covid-19 Memorial Service: https://youtu.be/_u6UdISOyw

Developing Leaders, Not Followers

Many higher education institutions are attempting to discover ways to create that elusive balance required for young people to become self-reflective, highly prepared leaders in the world we know today. Because in today\u27s global economy, we need to encourage all of our graduates to lead, while also providing them with the skills required to do so

Constructing a distributed AUV network for underwater plume-tracking operations

© The Author(s), 2012. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in International Journal of Distributed Sensor Networks 2012 (2012): 191235, doi:10.1155/2012/191235.In recent years, there has been significant concern about the impacts of offshore oil spill plumes and harmful algal blooms on the coastal ocean environment and biology, as well as on the human populations adjacent to these coastal regions. Thus, it has become increasingly important to determine the 3D extent of these ocean features (“plumes”) and how they evolve over time. The ocean environment is largely inaccessible to sensing directly by humans, motivating the need for robots to intelligently sense the ocean for us. In this paper, we propose the use of an autonomous underwater vehicle (AUV) network to track and predict plume shape and motion, discussing solutions to the challenges of spatiotemporal data aliasing (coverage versus resolution), underwater communication, AUV autonomy, data fusion, and coordination of multiple AUVs. A plume simulation is also developed here as the first step toward implementing behaviors for autonomous, adaptive plume tracking with AUVs, modeling a plume as a sum of Fourier orders and examining the resulting errors. This is then extended to include plume forecasting based on time variations, and future improvements and implementation are discussed.This research was made with Government support under and awarded by DoD, Air Force Office of Scientific Research, National Defense Science and Engineering Graduate (NDSEG) Fellowship, 32 CFR 168a

Factor VIII:C concentrate purified from plasma using monoclonal antibodies: human studies

Conventional clotting factor concentrates have, until recently, been of intermediate purity, containing less than 1% of the coagulation factor, and greater than 99% extraneous plasma proteins such as fibrinogen, fibronectin, gamma globulins, and traces of many others. We report here the results of a new factor VIII concentrate that is purified from human plasma using a mouse monoclonal antibody to factor VIII:vWF in an affinity chromatography system. The resultant concentrate has an activity of between 3,000 and 5,000 U/mg protein before albumin is added as a stabilizer. Seven patients with severe hemophilia A and no inhibitor who were positive for antibody to human immunodeficiency virus (HIV) have been treated solely with this concentrate for over 24 months. Factor usage in these patients has ranged from 611 U/kg/yr to 2,022 U/kg/yr. These patients have infused approximately once per week on the average, most often for joint hemorrhages. The efficacy of the concentrate is excellent. No allergic reactions have occurred and no factor VIII antibodies have developed. In these seven patients mean CD4 counts stabilized (856 +/- 619 at screen v 778 +/- 686 at 24 months) and there was reversal of skin test anergy. In a comparison group on conventional intermediate purity concentrate chosen retrospectively decreases in mean CD4 cell counts similarly did not occur. However, the number of the comparison patients who were anergic increased over the course of the study. These observations indicate the possibility that more highly purified concentrates may stabilize immune function in HIV seropositive patients

Applications of the ARGUS code in accelerator physics

ARGUS is a three-dimensional, electromagnetic, particle-in-cell (PIC) simulation code that is being distributed to U.S. accelerator laboratories in collaboration between SAIC and the Los Alamos Accelerator Code Group. It uses a modular architecture that allows multiple physics modules to share common utilities for grid and structure input., memory management, disk I/O, and diagnostics, Physics modules are in place for electrostatic and electromagnetic field solutions., frequency-domain (eigenvalue) solutions, time- dependent PIC, and steady-state PIC simulations. All of the modules are implemented with a domain-decomposition architecture that allows large problems to be broken up into pieces that fit in core and that facilitates the adaptation of ARGUS for parallel processing ARGUS operates on either Cray or workstation platforms, and MOTIF-based user interface is available for X-windows terminals. Applications of ARGUS in accelerator physics and design are described in this paper