Global Impacts from Improved Tropical Forages: A Meta-Analysis Revealing Overlooked Benefits and Costs, Evolving Values and New Priorities

The wider use and improved performance of planted tropical forages can substantially change social, economic and environmental landscapes. By reviewing impact-related studies published in the past two decades, this paper shows how evolving development priorities have influenced the types of impacts being documented. A meta-analysis was used to examine 98 studies according to: (1) breadth of reported effects, as related to development goals of social equity, economic growth and environmental sustainability; (2) extent of effects, ranging from intermediate to longer-term impacts; and (3) measurement precision (identification, description and quantification). Impacts have been assessed for fewer than half of the documented 118M ha with improved forages. Although Brazil accounts for 86% of the known planted area, widespread irregular reporting of technology adoption affects accuracy of global estimates. Over 80% of the impact-related studies reported economic effects, while fewer than 20% were quantitative estimates of longer-term economic impacts. Inconsistent valuation methods and assumptions prevented valid summation of total economic impacts. Social effects were reported in fewer than 60% of studies and emphasised household-level outcomes on gender and labour, with most reported effects being non-quantitative. Environmental effects were reported slightly more often than social effects, with recent increases in quantitative estimates of carbon accumulation. Few studies analysed tradeoffs. Independent reviewers conducted approximately 15% of the studies. Newer development priorities of environmental sustainability, system intensification, organisational participation and innovation capacities require broader approaches to assess impacts. Increased marketing and coordination with development and environmental organisations can generate greater demands for improved forages

The potential impact of Ocean Thermal Energy Conversion (OTEC) on fisheries

The commercial development of ocean thermal energy conversion (OTEC) operations will involve some environmental perturbations for which there is no precedent experience. The pumping of very large volumes of warm surface water and cold deep water and its subsequent discharge will result in the impingement, entrainment, and redistribution of biota. Additional stresses to biota will be caused by biocide usage and temperature depressions. However, the artificial upwelling of nutrients associated with the pumping of cold deep water, and the artificial reef created by an OTEC plant may have positive effects on the local environment. Although more detailed information is needed to assess the net effect of an OTEC operation on fisheries, certain assumptions and calculations are made supporting the conclusion that the potential risk to fisheries is not significant enough to deter the early development of IDEe. It will be necessary to monitor a commercial-scale plant in order to remove many of the remaining uncertainties. (PDF file contains 39 pages.

Rational modification of an HIV-1 gp120 results in enhanced neutralization breadth when used as a DNA prime

Background The identification of phenotypic features of the HIV-1 envelope glycoprotein that correlate with neutralization breadth is an important goal of HIV vaccine research. Recently we compared the immunogenic potential of two gp120s differing in their ability to utilize CD4; B33 (highly macrophage topic) and LN40 (non-macrophage tropic). Using a DNA prime protein boost regimen in New Zealand White Rabbits, LN40-primed sera displayed enhanced breadth compared to the B33-primed group, with differences in immunogenicity between groups modulated by specific residues within and flanking the V3 loop and the CD4bs. To better understand the role of these residues in eliciting breadth, we introduced reciprocal mutations between LN40 and B33 at these critical positions. Methods Three groups of four rabbits were primed with one of three chimeric LN40/B33 gp120 DNAs, followed by a polyvalent protein boost. Time course and endpoint titers were determined via ELISA. Neutralization breadth was analyzed by Monogram against a panel of sixteen viruses using a Phenosense neutralization assay. Anti-gp120 serum specificities were determined using a set of overlapping peptides spanning the entire gp120 via ELISA. Results We found that sera primed with a B33 chimera containing specific LN40 residues within the V3 loop and the CD4 binding loop displayed enhanced neutralization breadth against a cross-clade panel of Tier 1 and 2 viruses compared to the B33-primed group. Interestingly, a second B33 chimera containing two additional LN40 substitutions (Stu-Bsu R373/N386) within C3/V4 primed the broadest response, being broader than even the LN40-primed group. Additionally, peptide ELISAs showed differences in reactivity between priming groups which were most pronounced for the C3/V4 region, suggesting an important role for these regions in modulating serum antibody responses against gp120

Effect of Local Norms on Racial and Ethnic Representation in Gifted Education

Educators have sought to understand and address the disproportional representation of students from certain student subgroups in gifted education. Most gifted identification decisions are made with national comparisons where students must score above a certain percentage of test takers. However, this approach is not always consistent with the overall goal of gifted education. Scholars have long argued for the use of local normative criteria to increase the diversity of students identified for gifted services, and although some districts across the country have applied such recommendations, little research has been carried out. In this study, we use a large data set to assess the extent to which identifying gifted students with either school-level norms or a combination of national and school-level norms would improve gifted education representation rates for students who are from African American and Latinx families. A preprint of this registered report and this project’s preregistration documentation are available at https://osf.io/z2egy/

Partnering for Quail in South Carolina: A Cooperative Approach Making a Difference

The National Bobwhite Conservation Initiative (NBCI) identified 15 national quail focal areas throughout the distribution of the northern bobwhite (Colinus virginianus) in June 2016. The first NBCI Focal Area on U.S. Forest Service System land emerged from the existing 16,200-hectare Indian Creek Woodland and Savanna Restoration Initiative (ICWSRI). The ICWSRI is an ongoing collaborative project involving partners from 10 agencies and organizations in the Piedmont of South Carolina. Cooperation among federal and state agencies, non-governmental organizations (NGO), and private landowners, combined with assistance programs such as the Environmental Quality Incentives Program (EQIP) have currently resulted in 2,547 hectares (1,600 hectares on private land and 947 hectares on public land) of improved habitat for wildlife species associated with pine woodlands and savannas. Data obtained through the Breeding Bird Survey, spring whistle counts, and fall covey counts suggest a correlation between woodland and savanna restoration and avian response across the ICWSRI area. Fall covey count minimum population estimates (birds/ha) ranged from 1/38 in 2008 to 1/7 in 2016. Spring whistle count population density estimates (birds/ha) ranged from 1/37 in 2009 to 1/6 in 2012. Although monitoring suggests an initial increase in bobwhite densities across the project area, it is imperative to continue involving existing and additional partners to increase habitat availability, connectivity, and quality for bobwhite and associated species. Collaborative efforts and partnerships across ownership boundaries are necessary to increase bobwhite populations on a landscape scale. The Indian Creek project has effectively involved efforts from federal, state, NGO, and private partners to restore and improve bobwhite habitat and may serve as an example for other areas where incorporating a cooperative approach could positively influence bobwhite populations

Проблема коррупции в современном обществе

Abstract Background Agricultural workers may be exposed to potential carcinogens including pesticides, sensitizing agents and solar radiation. Previous studies indicate increased risks of hematopoietic cancers and decreased risks at other sites, possibly due to differences in lifestyle or risk behaviours. We present findings from CanCHEC (Canadian Census Health and Environment Cohort), the largest national population-based cohort of agricultural workers. Methods Statistics Canada created the cohort using deterministic and probabilistic linkage of the 1991 Canadian Long Form Census to National Cancer Registry records for 1992–2010. Self-reported occupations were coded using the Standard Occupational Classification (1991) system. Analyses were restricted to employed persons aged 25–74 years at baseline (N = 2,051,315), with follow-up until December 31, 2010. Hazard ratios (HR) and 95% confidence intervals (CI) were modeled using Cox proportional hazards for all workers in agricultural occupations (n = 70,570; 70.8% male), stratified by sex, and adjusted for age at cohort entry, province of residence, and highest level of education. Results A total of 9515 incident cancer cases (7295 in males) occurred in agricultural workers. Among men, increased risks were observed for non-Hodgkin lymphoma (HR = 1.10, 95% CI = 1.00–1.21), prostate (HR = 1.11, 95% CI = 1.06–1.16), melanoma (HR = 1.15, 95% CI = 1.02–1.31), and lip cancer (HR = 2.14, 95% CI = 1.70–2.70). Decreased risks in males were observed for lung, larynx, and liver cancers. Among female agricultural workers there was an increased risk of pancreatic cancer (HR = 1.36, 95% CI = 1.07–1.72). Increased risks of melanoma (HR = 1.79, 95% CI = 1.17–2.73), leukemia (HR = 2.01, 95% CI = 1.24–3.25) and multiple myeloma (HR = 2.25, 95% CI = 1.16–4.37) were observed in a subset of female crop farmers. Conclusions Exposure to pesticides may have contributed to increased risks of hematopoietic cancers, while increased risks of lip cancer and melanoma may be attributed to sun exposure. The array of decreased risks suggests reduced smoking and alcohol consumption in this occupational group compared to the general population

Adaptation of Proteins to the Cold in Antarctic Fish: A Role for Methionine?

The evolution of antifreeze glycoproteins has enabled notothenioid fish to flourish in the freezing waters of the Southern Ocean. Whereas successful at the biodiversity level to life in the cold, paradoxically at the cellular level these stenothermal animals have problems producing, folding, and degrading proteins at their ambient temperatures of -1.86 °C. In this first multi-species transcriptome comparison of the amino acid composition of notothenioid proteins with temperate teleost proteins, we show that, unlike psychrophilic bacteria, Antarctic fish provide little evidence for the mass alteration of protein amino acid composition to enhance protein folding and reduce protein denaturation in the cold. The exception was the significant overrepresentation of positions where leucine in temperate fish proteins was replaced by methionine in the notothenioid orthologues. We hypothesize that these extra methionines have been preferentially assimilated into the genome to act as redox sensors in the highly oxygenated waters of the Southern Ocean. This redox hypothesis is supported by analyses of notothenioids showing enrichment of genes associated with responses to environmental stress, particularly reactive oxygen species. So overall, although notothenioid fish show cold-associated problems with protein homeostasis, they may have modified only a selected number of biochemical pathways to work efficiently below 0 °C. Even a slight warming of the Southern Ocean might disrupt the critical functions of this handful of key pathways with considerable impacts for the functioning of this ecosystem in the future