Spectral Properties and Lifetimes of Neutral Spin-1/2-Fermions in a Magnetic Guide

We investigate the resonant motion of neutral spin-1/2-fermions in a magnetic guide. A wealth of unitary and anti-unitary symmetries is revealed in particular giving rise to a two-fold degeneracy of the energy levels. To compute the energies and decay widths of a large number of resonances the complex scaling method is employed. We discuss the dependence of the lifetimes on the angular momentum of the resonance states. In this context the existence of so-called quasi-bound states is shown. In order to approximately calculate the resonance energies of such states a radial Schr\"odinger equation is derived which improves the well-known adiabatic approximation. The effects of an additionally applied homogeneous Ioffe field on the resonance energies and decay widths are also considered. The results are applied to the case of the $^6\text{Li}$ atom in the $F=1/2$ hyperfine ground state.Comment: accepted for publication in PR

William King, Sir William Petty, and Post-War Ireland (1690–92): Sir Robert Southwell and the Printing of Political Discourse

This article analyses the production of printed political discourse between post-war Ireland and England, in particular Sir Robert Southwell’s leading role in bringing to publication William King’s The State of the Protestants and Sir William Petty’s The Political Anatomy of Ireland in 1691. The questions these two books raised for the settlement of Ireland and for the relationship between the two kingdoms of Ireland and England have become very important for Anglo-Irish political history yet their publication circumstances in 1691 have not been considered. The article argues that studying these circumstances, applying the methods of book history, and analysing carefully reception contexts reveals the ways that senior government figures used print for political and personal influence, demonstrates the growing role and sophistication of printed discourse in Anglo-Irish politics, and uncovers how networks of trusted friends and allies operating between kingdoms could be crucial for the production and favourable reception of political argument in print. These two detailed case studies offer new directions for thinking about precisely how and by whom political discourse was generated, how it circulated, and how it was received and understood in turbulent times, with church government, the constitutional relationship between kingdoms, and personal interests in flux and facing an uncertain future, towards the end of James II’s Ireland campaign

Reconsidering the quantization of electrodynamics with boundary conditions and some measurable consequences

We show that the commonly known conductor boundary conditions $E_{||}=B_\perp=0$ can be realized in two ways which we call 'thick' and 'thin' conductor. The 'thick' conductor is the commonly known approach and includes a Neumann condition on the normal component $E_\perp$ of the electric field whereas for a 'thin' conductor $E_\perp$ remains without boundary condition. Both types describe different physics already on the classical level where a 'thin' conductor allows for an interaction between the normal components of currents on both sides. On quantum level different forces between a conductor and a single electron or a neutral atom result. For instance, the Casimir-Polder force for a 'thin' conductor is by about 13% smaller than for a 'thick' one.Comment: 22 pages, basic statement weakened, conclusions changed, misprints correcte

Identification of false positive exercise tests with use of electrocardiographic criteria: A possible role for atrial repolarization waves

Atrial repolarization waves are opposite in direction to P waves, may have a magnitude of 100 to 200 mu V and may extend into the ST segment and T wave. It was postulated that exaggerated atrial repolarization waves during exercise could produce ST segment depression mimicking myocardial ischemia. The P waves, PR segments and ST segments were studied in leads II, III, aVF and V4 to V6 in 69 patients whose exercise electrocardiogram (ECG) suggested ischemia (100 mu V horizontal or 150 mu V upsloping ST depression 80 ms after the J point). All had a normal ECG at rest. The exercise test in 25 patients (52% male, mean age 53 years) was deemed false positive because of normal coronary arteriograms and left ventricular function (5 patients) or normal stress single photon emission computed tomographic thallium or gated blood pool scans (16 patients), or both (4 patients). Forty-four patients with a similar age and gender distribution, anginal chest pain and at least one coronary stenosis greater than or equal to 80% served as a true positive control group. The false positive group was characterized by (1) markedly downsloping PR segments at peak exercise, (2) longer exercise time and more rapidmore » peak exercise heart rate than those of the true positive group, and (3) absence of exercise-induced chest pain. The false positive group also displayed significantly greater absolute P wave amplitudes at peak exercise and greater augmentation of P wave amplitude by exercise in all six ECG leads than were observed in the true positive group.« les

Electromagnetic Momentum in Dispersive Dielectric Media

When the effects of dispersion are included, neither the Abraham nor the Minkowski expression for electromagnetic momentum in a dielectric medium gives the correct recoil momentum for absorbers or emitters of radiation. The total momentum density associated with a field in a dielectric medium has three contributions: (i) the Abraham momentum density of the field, (ii) the momentum density associated with the Abraham force, and (iii) a momentum density arising from the dispersive part of the response of the medium to the field, the latter having a form evidently first derived by D.F. Nelson [Phys. Rev. A 44, 3985 (1991)]. All three contributions are required for momentum conservation in the recoil of an absorber or emitter in a dielectric medium. We consider the momentum exchanged and the force on a polarizable particle (e.g., an atom or a small dielectric sphere) in a host dielectric when a pulse of light is incident upon it, including the dispersion of the dielectric medium as well as a dispersive component in the response of the particle to the field. The force can be greatly increased in slow-light dielectric media.Comment: 9 pages. To be published by Optics Communication

Comparison of three methods of extravascular lung water volume measurement in patients after cardiac surgery

This research was supported by an Intensive Care Society (UK) Young Investigator Award and unrestricted research grants from Barts and The London NHS Trust and LiDCO, Lt

The minor groove-binding agent ELB-21 forms multiple interstrand and intrastrand covalent cross-links with duplex DNA and displays potent bactericidal activity against methicillin-resistant Staphylococcus aureus

OBJECTIVES: The antistaphylococcal pyrrolobenzodiazepine dimer ELB-21 forms multiple adducts with duplex DNA through covalent interactions with appropriately spaced guanine residues; it is now known to form interstrand and intrastrand adducts with oligonucleotide sequences of variable length. We determined the DNA sequence preferences of ELB-21 in relation to its capacity to exert a bactericidal effect by damaging DNA. METHODS: Formation of adducts by ELB-21 and 12- to 14-mer DNA duplexes was investigated using ion-pair reversed phase liquid chromatography and mass spectrometry. Drug-induced changes in gene expression were measured in prophage-free Staphylococcus aureus RN4220 by microarray analysis. RESULTS: ELB-21 preferentially formed intrastrand adducts with guanines separated by three nucleotide base pairs. Interstrand and intrastrand adducts were formed with duplexes both longer and shorter than the preferred target sequences. ELB-21 elicited rapid bactericidal effects against prophage-carrying and prophage-free S. aureus strains; cell lysis occurred following activation and release of resident prophages. Killing appeared to be due to irreparable damage to bacterial DNA and susceptibility to ELB-21 was governed by the capacity of staphylococci to repair DNA lesions through induction of the SOS DNA damage response mediated by the RecA-LexA pathway. CONCLUSIONS: The data support the contention that ELB-21 arrests DNA replication, eliciting formation of ssDNA-RecA filaments that inactivate LexA, the SOS repressor, and phage repressors such as Cl, resulting in activation of the DNA damage response and de-repression of resident prophages. Above the MIC threshold, DNA repair is ineffective