Goal enablers: Evidence-based ways to turn your goals into reality

Goal setting research shows that specific, challenging goals do not always enhance performance. People can become distracted, discouraged, or otherwise diverted from effective goal pursuit. Decades of goal setting research, however, has identified factors that enable attainment of specific, challenging goals. These include the extent of commitment to the goal, access to adequate resources, possessing appropriate knowledge and skills, and feedback about goal progress. We explain how to apply a dozen evidence-based goal enablers to enhance your goal pursuit. We offer four categories of advice: (1) set relevant goals; (2) build resilient internal motivation; (3) craft an enabling context; and (4) proactively manage obstacles to attaining your goals. Some of these goal enablers may seem familiar to you. Yet many executives and students comment that most are rarely considered even when striving to attain high-priority professional, career, or personal goals

Implications of Mindset on Professional Development of Army Soldiers

Noncommissioned officers NCOs play a critical role in the professional development of junior enlisted JE Soldiers. Although the Army provides NCOs with tools and resources to help them effectively develop JE Soldiers, challenges in this area persist. To help the Army better understand and address these challenges, this report reviews research on mindset, defined as the beliefs that people hold about the fixedness or malleability of peoples traits and abilities. Mindset has been shown to have important implications for professional development outside of military contexts and may offer a novel solution for improving Soldier professional development outcomes. We detail findings from academic publications that describe how mindset has been conceptualized and measured in previous research, the effects of mindset on important individual and group-level outcomes, and how mindsets can be changed through targeted interventions. We also include findings from military-specific publications describing how mindset has been discussed in military contexts. We conclude with how insights from mindset theory and research could be applied to the Army context to create an Army-specific mindset measure, to inform the development of an intervention to foster growth mindset among NCOs, and to improve professional development in the Army more broadly

Consensus molecular subtype differences linking colon adenocarcinoma and obesity revealed by a cohort transcriptomic analysis

Colorectal cancer (CRC) is the third-leading cause of cancer-related deaths in the United States and worldwide. Obesity—a worldwide public health concern—is a known risk factor for cancer including CRC. However, the mechanisms underlying the link between CRC and obesity have yet to be fully elucidated in part because of the molecular heterogeneity of CRC. We hypothesized that obesity modulates CRC in a consensus molecular subtype (CMS)-dependent manner. RNA-seq data and associated tumor and patient characteristics including body weight and height data for 232 patients were obtained from The Cancer Genomic Atlas–Colon Adenocarcinoma (TCGA-COAD) database. Tumor samples were classified into the four CMSs with the CMScaller R package; body mass index (BMI) was calculated and categorized as normal, overweight, and obese. We observed a significant difference in CMS categorization between BMI categories. Differentially expressed genes (DEGs) between obese and overweight samples and normal samples differed across the CMSs, and associated prognostic analyses indicated that the DEGs had differing associations on survival. Using Gene Set Enrichment Analysis, we found differences in Hallmark gene set enrichment between obese and overweight samples and normal samples across the CMSs. We constructed Protein-Protein Interaction networks and observed differences in obesity-regulated hub genes for each CMS. Finally, we analyzed and found differences in predicted drug sensitivity between obese and overweight samples and normal samples across the CMSs. Our findings support that obesity impacts the CRC tumor transcriptome in a CMS-specific manner. The possible associations reported here are preliminary and will require validation using in vitro and animal models to examine the CMS-dependence of the genes and pathways. Once validated the obesity-linked genes and pathways may represent new therapeutic targets to treat colon cancer in a CMS-dependent manner

Neurological Signs at the First Psychotic Episode as Correlates of Long-Term Outcome:Results From the AESOP-10 Study

Minor neurological signs are subtle deficits in sensory integration, motor coordination, and sequencing of complex motor acts present in excess in the early stages of psychosis. Still, it remains unclear whether at least some of these signs represent trait or state markers for psychosis and whether they are markers of long-term disease outcome of clinical utility. We examined the relationship between neurological function at illness onset assessed with the Neurological Evaluation Scale and subsequent illness course in 233 patients from AESOP-10 (Aetiology and Ethnicity in Schizophrenia and Other Psychoses), a 10-year follow-up study of a population-based cohort of individuals recruited at the time of their first episode of psychosis in the United Kingdom. In 56 of these patients, we also explored changes in neurological function over time. We included a group of 172 individuals without psychosis as controls. After 10 years, 147 (63%) patients had developed a non-remitting course of illness, and 86 (37%) a remitting course. Already at first presentation, patients who developed a non-remitting course had significantly more primary, motor coordination, and total signs than both remitting patients and healthy controls. While Motor Coordination signs did not change over time, rates of Primary, Sensory Integration, and Total signs increased, independently of illness course type. These findings suggest that motor coordination problems could be a useful early, quick, and easily detectable marker of subsequent clinical outcome. With other motor abnormalities, a measure of motor incoordination could contribute to the identification of the most vulnerable individuals, who could benefit from targeted and more assertive treatment approaches

Symptom remission at 12-weeks strongly predicts long-term recovery from the first episode of psychosis.

BACKGROUND: To determine the baseline individual characteristics that predicted symptom recovery and functional recovery at 10-years following the first episode of psychosis. METHODS: AESOP-10 is a 10-year follow up of an epidemiological, naturalistic population-based cohort of individuals recruited at the time of their first episode of psychosis in two areas in the UK (South East London and Nottingham). Detailed information on demographic, clinical, and social factors was examined to identify which factors predicted symptom and functional remission and recovery over 10-year follow-up. The study included 557 individuals with a first episode psychosis. The main study outcomes were symptom recovery and functional recovery at 10-year follow-up. RESULTS: At 10 years, 46.2% (n = 140 of 303) of patients achieved symptom recovery and 40.9% (n = 117) achieved functional recovery. The strongest predictor of symptom recovery at 10 years was symptom remission at 12 weeks (adj OR 4.47; CI 2.60-7.67); followed by a diagnosis of depression with psychotic symptoms (adj OR 2.68; CI 1.02-7.05). Symptom remission at 12 weeks was also a strong predictor of functional recovery at 10 years (adj OR 2.75; CI 1.23-6.11), together with being from Nottingham study centre (adj OR 3.23; CI 1.25-8.30) and having a diagnosis of mania (adj OR 8.17; CI 1.61-41.42). CONCLUSIONS: Symptom remission at 12 weeks is an important predictor of both symptom and functional recovery at 10 years, with implications for illness management. The concepts of clinical and functional recovery overlap but should be considered separately.This work was supported by UK Medical Research Council (ref: G0500817) and the Department of Health via the National Institute for Health Research (NIHR) Biomedical Research Centre at South London and Maudsley Foundation Trust (SLaM) and King’s College Londo

Low-intensity cognitive-behaviour therapy interventions for obsessive-compulsive disorder compared to waiting list for therapist-led cognitive-behaviour therapy: 3-arm randomised controlled trial of clinical effectiveness

Background Obsessive-compulsive disorder (OCD) is prevalent and without adequate treatment usually follows a chronic course. “High-intensity” cognitive-behaviour therapy (CBT) from a specialist therapist is current “best practice.” However, access is difficult because of limited numbers of therapists and because of the disabling effects of OCD symptoms. There is a potential role for “low-intensity” interventions as part of a stepped care model. Low-intensity interventions (written or web-based materials with limited therapist support) can be provided remotely, which has the potential to increase access. However, current evidence concerning low-intensity interventions is insufficient. We aimed to determine the clinical effectiveness of 2 forms of low-intensity CBT prior to high-intensity CBT, in adults meeting the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) criteria for OCD. Methods and findings This study was approved by the National Research Ethics Service Committee North West–Lancaster (reference number 11/NW/0276). All participants provided informed consent to take part in the trial. We conducted a 3-arm, multicentre randomised controlled trial in primary- and secondary-care United Kingdom mental health services. All patients were on a waiting list for therapist-led CBT (treatment as usual). Four hundred and seventy-three eligible patients were recruited and randomised. Patients had a median age of 33 years, and 60% were female. The majority were experiencing severe OCD. Patients received 1 of 2 low-intensity interventions: computerised CBT (cCBT; web-based CBT materials and limited telephone support) through “OCFighter” or guided self-help (written CBT materials with limited telephone or face-to-face support). Primary comparisons concerned OCD symptoms, measured using the Yale-Brown Obsessive Compulsive Scale–Observer-Rated (Y-BOCS-OR) at 3, 6, and 12 months. Secondary outcomes included health-related quality of life, depression, anxiety, and functioning. At 3 months, guided self-help demonstrated modest benefits over the waiting list in reducing OCD symptoms (adjusted mean difference = −1.91, 95% CI −3.27 to −0.55). These effects did not reach a prespecified level of “clinically significant benefit.” cCBT did not demonstrate significant benefit (adjusted mean difference = −0.71, 95% CI −2.12 to 0.70). At 12 months, neither guided self-help nor cCBT led to differences in OCD symptoms. Early access to low-intensity interventions led to significant reductions in uptake of high-intensity CBT over 12 months; 86% of the patients allocated to the waiting list for high-intensity CBT started treatment by the end of the trial, compared to 62% in supported cCBT and 57% in guided self-help. These reductions did not compromise longer-term patient outcomes. Data suggested small differences in satisfaction at 3 months, with patients more satisfied with guided self-help than supported cCBT. A significant issue in the interpretation of the results concerns the level of access to high-intensity CBT before the primary outcome assessment. Conclusions We have demonstrated that providing low-intensity interventions does not lead to clinically significant benefits but may reduce uptake of therapist-led CBT

Better than Brainstorming? Potential Contextual Boundary Conditions to Brainwriting for Idea Generation in Organizations

Organizations and societies all need good, useful ideas to survive and prosper. People often enjoy brainstorming, though it is not as productive as they tend to believe. Groups can potentially generate more and better ideas when brainwriting ; that is, silently sharing written ideas in a time- and sequence-structured group format. This conceptual paper identifies likely boundary conditions to the promising findings from brainwriting laboratory research generalizing to real-world organizational contexts. Important dimensions of organizational context may be revealed by drawing on the journalistic principle to examine what, who, when, where, and why certain outcomes result from particular organizational practices (Johns, 2006). Multiple potential contextual moderators are suggested in each of these five areas. Subsequent field research will inform the idea generation literature as well as those concerned with eliciting high quality, useful ideas to address particular organizational and societal challenges

Better than Brainstorming? Potential Contextual Boundary Conditions to Brainwriting for Idea Generation in Organizations

Organizations and societies all need good, useful ideas to survive and prosper. People often enjoy brainstorming, though it is not as productive as they tend to believe. Groups can potentially generate more and better ideas when brainwriting ; that is, silently sharing written ideas in a time- and sequence-structured group format. This conceptual paper identifies likely boundary conditions to the promising findings from brainwriting laboratory research generalizing to real-world organizational contexts. Important dimensions of organizational context may be revealed by drawing on the journalistic principle to examine what, who, when, where, and why certain outcomes result from particular organizational practices (Johns, 2006). Multiple potential contextual moderators are suggested in each of these five areas. Subsequent field research will inform the idea generation literature as well as those concerned with eliciting high quality, useful ideas to address particular organizational and societal challenges

Managers\u27 Implicit Assumptions About Personnel

Effective managers recognize both positive and negative changes in employee performance and take appropriate remedial action when required. Managers\u27 assumptions about the rigidity or malleability of personal attributes (e.g., ability and personality) affect their performance of these critical personnel management tasks. To the extent that managers assume that personal attributes are fixed traits that are largely stable over time, they tend to inadequately recognize actual changes in employee performance and are disinclined to coach employees regarding how to improve their performance. However, a growth-mindset intervention can lead managers to relinquish their fixed mindset and subsequently provide more accurate performance appraisals and helpful employee coaching. Implications for performance evaluation procedures and avenues for future research are outlined

Managers\u27 Implicit Assumptions About Personnel

Effective managers recognize both positive and negative changes in employee performance and take appropriate remedial action when required. Managers\u27 assumptions about the rigidity or malleability of personal attributes (e.g., ability and personality) affect their performance of these critical personnel management tasks. To the extent that managers assume that personal attributes are fixed traits that are largely stable over time, they tend to inadequately recognize actual changes in employee performance and are disinclined to coach employees regarding how to improve their performance. However, a growth-mindset intervention can lead managers to relinquish their fixed mindset and subsequently provide more accurate performance appraisals and helpful employee coaching. Implications for performance evaluation procedures and avenues for future research are outlined