Quantum noise induced entanglement and chaos in the dissipative quantum model of brain

We discuss some features of the dissipative quantum model of brain in the frame of the formalism of quantum dissipation. Such a formalism is based on the doubling of the system degrees of freedom. We show that the doubled modes account for the quantum noise in the fluctuating random force in the system-environment coupling. Remarkably, such a noise manifests itself through the coherent structure of the system ground state. The entanglement of the system modes with the doubled modes is shown to be permanent in the infinite volume limit. In such a limit the trajectories in the memory space are classical chaotic trajectories.Comment: 14 page

Nitrogen-enhanced indium segregation in (Ga,In)(N,As)/GaAs multiple quantum wells grown by molecular-beam epitaxy

Transmission electron microscopy (TEM) is used to determine the composition of quaternary (Ga,In)(N,As) quantum wells (QWs). Through a combined analysis of the chemically sensitive (002) dark-field (DF) images and the lattice-resolving high-resolution TEM images, the local distributions of nitrogen and indium in the growth direction are determined. In particular, we are able to directly detect the existence of indium segregation in (Ga,In)(N,As) QWs. A comparison with the indium distribution profile in the nitrogen-free (In,Ga)As QWs, grown under similar conditions, revealed that incorporating N into the alloy enhanced indium segregation

Laboratorio online: tutoring e vantaggi per lo studente universitario

Il presente lavoro nasce con l’intento di realizzare una ricerca che ha come obiettivo principale quello di analizzare la funzione del tutoring e dei laboratori online su un gruppo di matricole frequentanti il primo anno del Corso di Laurea di Scienze dell’Educazione dell’Università di Cagliari. In tali attività, ruolo cruciale è svolto dal tutor online che funge da facilitatore e contribuisce a chiarire e a raggiungere il conseguimento degli obiettivi educativi e delle interazioni. Il tutor induce lo sviluppo di apprendimento autonomo dei singoli discenti, facendo leva sulla loro curiosità, individuando il loro bisogni formativi, formulando obiettivi compatibili con le loro possibilità e identificando le risorse per loro più adeguate. Partendo da questi presupposti ci siamo chiesti quale sia stata la soddisfazione generale sul ruolo del tutor e l’efficacia del laboratorio in termini di percezione dell’aumento delle proprie abilità di problem solving, dell’autostima, della motivazione, del locus of control e delle competenze informatiche. In generale, si può affermare che l’esperienza del laboratorio di didattica si è rivelata positiva e ha rappresentato un elemento di supporto per gli studenti che vi hanno partecipato

Use of training with BCI (Brain Computer Interface) in the management of impulsivity

Impulsivity represents one of the risk factors strongly related to dependent behavior in subjects with a diagnosis of substance dependence. The risk appetite, in particular, represents a construct connected with other components such as jumping to conclusion and risk taking.There are several forms of treatment used with subjects who have problems related to impulsivity. A good part of these is aimed at subjects with ADHD (Attention Deficit Hyperactivity Disorder), in the form of training or exercises implemented on software. This work aims to evaluate the use of training for concentration, attention and meditation on reducing risk appetite. The experimental design, of a pre-post type, involves assessing the risk appetite before and after training, to be carried out in six sessions over two weeks. The comparison between the experimental group and the control groups showed significant efficacy in reducing the levels of impulsivity in subjects with addiction.This work represents a pilot study on the possible use of meditation, concentration, and training exercises and demonstrates how these can be considered as excellent forms of training for the reduction of impulsiveness and risk appetite, showing their feasibility in the contexts of intervention and cure for addictions

Brain Endothelial Cells Activate Neuroinflammatory Pathways in Response to Early Cerebral Small Vessel Disease (CSVD) Patients’ Plasma

The pathogenesis of cerebral small vessel disease (CSVD) is largely unknown. Endothelial disfunction has been suggested as the turning point in CSVD development. In this study, we tested the effect of plasma from CSVD patients on human cerebral microvascular endothelial cells with the aim of describing the pattern of endothelial activation. Plasma samples from three groups of young subjects have been tested: PTs (subjects affected by early stage CSVD); CTRLs (control subjects without abnormalities at MRI scanning); BDs (blood donors). Human Brain Endothelial Cells 5i (HBEC5i) were treated with plasma and total RNA was extracted. RNAs were pooled to reduce gene expression-based variability and NGS analysis was performed. Differentially expressed genes were highlighted comparing PTs, CTRLs and BDs with HBEC5i untreated cells. No significantly altered pathway was evaluated in BD-related treatment. Regulation of p38 MAPK cascade (GO:1900744) was the only pathway altered in CTRL-related treatment. Indeed, 36 different biological processes turned out to be deregulated after PT treatment of HBEC5i, i.e., the cytokine-mediated signaling pathway (GO:0019221). Endothelial cells activate inflammatory pathways in response to stimuli from CSVD patients' plasma, suggesting the pathogenetic role of neuroinflammation from the early asymptomatic phases of cerebrovascular disease

Innovating home visiting to mothers and infants by community health workers: an action-oriented guide

Abstract Objectives: to describe the process of development and the structure of an action-oriented guide for home visits (HVs) to mothers and infants by Community Health Workers (CHWs). The guide was adopted in a controlled trial aimed at assessing its efficacy in improving CHWs' performance. Methods: steps to develop the guide included: 1) Review of international and national standards and recommendations for community interventions for maternal and child care; 2) Assessment of perceived needs of CHWs and other Family Health professionals regarding prenatal and postnatal HVs; 3) Identification of elements to construct the guide. Results: the Guide provides action-oriented instructions for 10 HVs during prenatal and postnatal period up to 9 months instead of the 18 HVs currently recommended by Ministry of Health. Specific tasks for each visit including assessment and promotion of early child development (ECD) and an action-oriented risk classification are introduced as standardized operational practice. Conclusions: the described approach to guide construction allows adapting the guide contents to the health system context in Brazil and other countries interested in improving quality of HVs by CHWs. The guide, by identifying tasks to be carried out and actions to be taken at each HV, provides an innovative approach and represents a requisite for a more efficient and effective use of their time

Sviluppo di tecniche di simulazione eterogenea funzionale e numerica applicate all’ingegneria di sistemi aeronautici

Questo studio illustra l’impiego del ‘Model Based Systems Engineering’ (MBSE), in cui strumenti di modellazione funzionale si integrano con modelli numerici, da tempo impiegati in progettazione, per la realizzazione di sistemi complessi. E’ analizzato un sistema antighiaccio aeronautico, sviluppato nell’ambito del progetto ‘CRYSTAL’. L’obiettivo è stato raggiunto collegando il gestore di requisiti IBM DOORS®, IBM RHAPSODY®, che opera in ambiente SysML, e SIMULINK® o DYMOLA®. L’interoperabilità è stata garantita dallo standard di connessione Functional Mock–up Interface (FMI), che ha permesso di validare il processo realizzando la cosiddetta ‘simulazione eterogenea’ di modelli funzionali e numerici integrati

PHANGS CO kinematics: disk orientations and rotation curves at 150 pc resolution

We present kinematic orientations and high resolution (150 pc) rotation curves for 67 main sequence star-forming galaxies surveyed in CO (2-1) emission by PHANGS-ALMA. Our measurements are based on the application of a new fitting method tailored to CO velocity fields. Our approach identifies an optimal global orientation as a way to reduce the impact of non-axisymmetric (bar and spiral) features and the uneven spatial sampling characteristic of CO emission in the inner regions of nearby galaxies. The method performs especially well when applied to the large number of independent lines-of-sight contained in the PHANGS CO velocity fields mapped at 1'' resolution. The high resolution rotation curves fitted to these data are sensitive probes of mass distribution in the inner regions of these galaxies. We use the inner slope as well as the amplitude of our fitted rotation curves to demonstrate that CO is a reliable global dynamical mass tracer. From the consistency between photometric orientations from the literature and kinematic orientations determined with our method, we infer that the shapes of stellar disks in the mass range of log($\rm M_{\star}(M_{\odot})$)=9.0-10.9 probed by our sample are very close to circular and have uniform thickness.Comment: 19 figures, 36 pages, accepted for publication in ApJ. Table of PHANGS rotation curves available from http://phangs.org/dat

<i>Zygomaticus major</i> muscle bony attachment site:a Thiel-embalmed cadaver study

Objective: Thezygomaticus major is a principal muscle of facial expression which is engaged when smiling. The zygomaticus major origin of the zygomatic bone is often discussed relevant to its importance in the field of plastic surgery. In addition, the zygomaticus major attachment site is also significant for forensic craniofacial reconstruction, separating the cheek into frontal and lateral surfaces. However, there are discrepancies amongst published articles regarding the precise origin of the zygomaticus major muscle. The aim of this study is to investigate more distinctive and palpable landmarks as the bony attachment of the zygomaticus major. Methods: This project is the first zygomaticus major dissection study utilising Thiel embalmed cadavers. Fifty-two facial dissections were investigated in 26 Thiel embalmed bodies, bequeathed to the Centre for Anatomy and Human Identification at The University of Dundee between 2013 and 2015. Results: This study found that the origin of zygomaticus major muscle was located at the superior margin of the temporal process on the lateral surface of zygomatic bone. Moreover, the zygomaticus major muscle overlapped the anterosuperior border of the masseter muscle. One out of 52 zygomaticus major muscles presented bifurcation. Conclusion: The origin site of zygomaticus major is considered important to increase resemblance in forensic craniofacial reconstruction. Furthermore, since zygomaticus major is a salient muscle involved in facial expression, the potential effects for cosmetic/surgical procedures are also relevant to the medical field and successful surgical outcomes. The current study provided easily palpable landmarks of zygomaticus major origin site which is beneficial for both surgeons and forensic craniofacial reconstruction practitioners. © 202

Dissipation and spontaneous symmetry breaking in brain dynamics

We compare the predictions of the dissipative quantum model of brain with neurophysiological data collected from electroencephalograms resulting from high-density arrays fixed on the surfaces of primary sensory and limbic areas of trained rabbits and cats. Functional brain imaging in relation to behavior reveals the formation of coherent domains of synchronized neuronal oscillatory activity and phase transitions predicted by the dissipative model.Comment: Restyled, slight changes in title and abstract, updated bibliography, J. Phys. A: Math. Theor. Vol. 41 (2008) in prin