Dynamical Casimir-Polder energy between an excited and a ground-state atom

We consider the Casimir-Polder interaction between two atoms, one in the ground state and the other in its excited state. The interaction is time-dependent for this system, because of the dynamical self-dressing and the spontaneous decay of the excited atom. We calculate the dynamical Casimir-Polder potential between the two atoms using an effective Hamiltonian approach. The results obtained and their physical meaning are discussed and compared with previous results based on a time-independent approach which uses a non-normalizable dressed state for the excited atom.Comment: 11 page

Sas-4 colocalizes with the ciliary rootlets of the drosophila sensory organs

The Drosophila eye displays peculiar sensory organs of unknown function, the mechanosensory bristles, that are intercalated among the adjacent ommatidia. Like the other Drosophila sensory organs, the mechanosensory bristles consist of a bipolar neuron and two tandemly aligned centrioles, the distal of which nucleates the ciliary axoneme and represents the starting point of the ciliary rootlets. We report here that the centriole associated protein Sas-4 colocalizes with the short ciliary rootlets of the mechanosensory bristles and with the elongated rootlets of chordotonal and olfactory neurons. This finding suggests an unexpected cytoplasmic localization of Sas-4 protein and points to a new underscored role for this protein. Moreover, we observed that the sheath cells associated with the sensory neurons also display two tandemly aligned centrioles but lacks ciliary axonemes, suggesting that the dendrites of the sensory neurons are dispensable for the assembly of aligned centrioles and rootlets

The Microtubule-Depolymerizing Kinesin-13 Klp10A Is Enriched in the Transition Zone of the Ciliary Structures of Drosophila melanogaster

The precursor of the flagellar axoneme is already present in the primary spermatocytes of Drosophila melanogaster. During spermatogenesis each primary spermatocyte shows a centriole pair that moves to the cell membrane and organizes an axoneme-based structure, the cilium-like region (CLR). The CLRs persist through the meiotic divisions and are inherited by young spermatids. During spermatid differentiation the ciliary caps elongate giving rise to the sperm axoneme. Mutations in Klp10A, a kinesin-13 of Drosophila, results in defects of centriole/CLR organization in spermatocytes and of ciliary cap assembly in elongating spermatids. Reduced Klp10A expression also results in strong structural defects of sensory type I neurons. We show, here, that this protein displays a peculiar localization during male gametogenesis. The Klp10A signal is first detected at the distal ends of the centrioles when they dock to the plasma membrane of young primary spermatocytes. At the onset of the first meiotic prometaphase, when the CLRs reach their full size, Klp10A is enriched in a distinct narrow area at the distal end of the centrioles and persists in elongating spermatids at the base of the ciliary cap. We conclude that Klp10A could be a core component of the ciliary transition zone in Drosophila

Cell-to-Cell Interactions during Early Drosophila Oogenesis: An Ultrastructural Analysis

Drosophila oogenesis requires the subsequent growth of distinct egg chambers each containing a group of sixteen germline cells surrounded by a simple epithelium of follicle cells. The oocyte occupies a posterior position within the germ cells, thus giving a distinct asymmetry to the egg chamber. Although this disposition is critical for the formation of the anterior-posterior axis of the embryo, the interplay between somatic and germ cells during the early stages of oogenesis remains an open question. We uncover by stage 2, when the egg chambers leaved the germarium, some unique spatial interactions between the posterior follicle cells and the oocyte. These interactions are restricted to the surface of the oocyte over the centriole cluster that formed during early oogenesis. Moreover, the posterior follicle cells in front of the oocyte display a convoluted apical membrane with extensive contacts, whereas the other follicle cells have a flat apical surface without obvious surface protrusions. In addition, the germ cells located at the posterior end of the egg chamber have very elongated protrusions that come into contact with each other or with facing follicle cells. These observations point to distinct polarization events during early oogenesis supporting previous molecular data of an inherent asymmetry between the anterior and the posterior regions of the egg chambers

Shock Tube Flows Past Partially Opened Diaphragms

Unsteady compressible flows resulting from the incomplete burst of the shock tube diaphragm are investigated both experimentally and numerically for different initial pressure ratios and opening diameters. The intensity of the shock wave is found to be lower than that corresponding to a complete opening. A heuristic relation is proposed to compute the shock strength as a function of the relative area of the open portion of the diaphragm. Strong pressure oscillations past the shock front are also observed. These multi-dimensional disturbances are generated when the initially normal shock wave diffracts from the diaphragm edges and reflects on the shock tube walls, resulting in a complex unsteady flow field behind the leading shock wave. The limiting local frequency of the pressure oscillations is found to be very close to the ratio of acoustic wave speed in the perturbed region to the shock tube diameter. The power associated with these pressure oscillations decreases with increasing distance from the diaphragm since the diffracted and reflected shocks partially coalesce into a single normal shock front. A simple analytical model is devised to explain the reduction of the local frequency of the disturbances as the distance from the leading shock increases

Early Drosophila Oogenesis: A Tale of Centriolar Asymmetry

Among the morphological processes that characterize the early stages of Drosophila oogenesis, the dynamic of the centrioles deserves particular attention. We re-examined the architecture and the distribution of the centrioles within the germarium and early stages of the vitellarium. We found that most of the germ cell centrioles diverge from the canonical model and display notable variations in size. Moreover, duplication events were frequently observed within the germarium in the absence of DNA replication. Finally, we report the presence of an unusually long centriole that is first detected in the cystoblast and is always associated with the developing oocyte. This centriole is directly inherited after the asymmetric division of the germline stem cells and persists during the process of oocyte selection, thus already representing a marker for oocyte identification at the beginning of its formation and during the ensuing developmental stages

The impact of market orientation on research-based spin off performance: emerging issues from an exploratory study

The paper addresses the relationship between Market Orientation (MO) and Research based spin offs' business performance, using a sample of 90 Italian RBSOs present in the Netval (Italian association for the valorisation of results from public research) database. The findings of the study may be useful for researchers and academics, advancing knowledge on Research based spin-offs (RBSOs) and the impact of MO on their performance, but also professionals from new high tech ventures and technology transfer offices may use these results to plan and design market-focused actions and support activities that will lead to improved business performance.The results could in fact indicate to entrepreneurs (or the entrepreneurial team) of this kind of firms which dimensions of MO deserve more attention in order to obtain a higher business performance

Surface Hopping Dynamics with the Frenkel Exciton Model in a Semiempirical Framework

We present an implementation of the Frenkel exciton model in the framework of the semiempirical floating occupation molecular orbitals-configuration interaction (FOMO-CI) electronic structure method, aimed at simulating the dynamics of multichromophoric systems, in which excitation energy transfer can occur, by a very efficient approach. The nonadiabatic molecular dynamics is here dealt with by the surface hopping method, but the implementation we proposed is compatible with other dynamical approaches. The exciton coupling is computed either exactly, within the semiempirical approximation considered, or by resorting to transition atomic charges. The validation of our implementation is carried out on the trans-azobenzeno-2S-phane (2S-TTABP), formed by two azobenzene units held together by sulfur bridges, taken as a minimal model of multichromophoric systems, in which both strong and weak exciton couplings are present