25 research outputs found
e Antigen, DNA polymerase activity, and infection of house-hold contacts with hepatitis B virus
No full textSolid lipid nanoparticles loading adefovir dipivoxil for antiviral therapy
No full textHerein, solid lipid nanoparticles (SLN) were proposed as a new drug delivery system for adefovir dipivoxil (ADV). The octadecylamine-fluorescein isothiocynate (ODA-FITC) was synthesized and used as a fluorescence maker to be incorporated into SLN to investigate the time-dependent cellular uptake of SLN by HepG2.2.15. The SLN of monostearin with ODA-FITC or ADV were prepared by solvent diffusion method in an aqueous system. About 15 wt% drug entrapment efficiency (EE) and 3 wt% drug loading (DL) could be reached in SLN loading ADV. Comparing with free ADV, the inhibitory effects of ADV loaded in SLN on hepatitis B surface antigen (HBsAg), hepatitis B e antigen (HBeAg) and hepatitis B virus (HBV) DNA levels in vitro were significantly enhanced
Systemic interferon alpha-2b increases the cure rate in laser treated patients with multiple persistent genital warts: a placebo-controlled study.
No full textThe effects of antiviral agents on serum hepatitis B e antigen levels in chronic type B hepatitis
No full textProtective Effect of Recombinant Interferon (IFN)-.ALPHA./.BETA. on MHV-2cc-induced Chronic Hepatitis in Athymic Nude Mice.
No full textThe long-term effects of lamivudine treatment in patients with HBeAg-negative liver cirrhosis
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