Bioactivity and Chemical Composition of the Essential Oils of Croton urucurana Baillon (Euphorbiaceae)

The essential oils from the stem barks and leaves of Croton urucurana Baillon (Euphorbiaceae) were analyzed by GC-FID and GC-MS. 100 compounds were identified and borneol (14.7%), bornyl acetate (5.2%), cadina-4,10(14)-dien-1 alpha-ol (14.7%), sesquicineole (10.5%) and gamma-gurjunene epoxide (5.4%) were the main components in essential oil from the steam barks. The oil from leaves was rich in sesquiterpenoids, mainly germacrene-D (15.2%) and bicyclogermacrene (36.4%). The in vitro cytotoxicity of the oils was evaluated against nine cancer cell lines and herbicidal effects against two seeds. The antimicrobial and antioxidant activities of the oils also were evaluated. The essential oil of stem bark was found to be more active than oil from leaves.123250261Fundacao de Apoio ao Desenvolvimento de EnsinoCiencia e Tecnologia de Mato Grosso do Sul (FUNDECT/MS)UFM

Chemical Composition and Biological Activities of Leaves Essential Oil From Schinus molle (Anacardiaceae)

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)The essential oil of Schinus molle (Anacardiaceae) obtained by hydrodistillation from the aerial parts, was analyzed by gas chromatography (GC), GC-mass spectrometry (MS) and nuclear magnetic resonance (NMR). The oil contains 69.1 % of sesquiterpenes and 20% of monoterpenes. The most abundant essential oil components were 1,8-cineole (7.6 %), terpin-4-ol (6.1 %), epi-alpha-cadinol (27.3 %), caryophyllene oxide (10.5 %), gamma-cadinene (9.1 %), spathulenol (8.6 %), 1,10-di-epi-cubenol (4.4 %) and 7-epi-alpha-eudesmol (2.3 %). The leaf essential oil showed pronounced in-vitro cytotoxic activity against K562 (0.89 mu g/mL) and NCI-ADR/RES (3.40 mu g/mL) human tumor cell lines. The antimicrobial, antioxidant and allelophathic activities of essential oil were also evaluated.145590599Fundacao de Apoio ao Desenvolvimento de EnsinoCiencia e Tecnologia de Mato Grosso do Sul (FUNDECT-MS)UFMSConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)DCRConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq

Antimicrobial activity and chemical investigation of Brazilian Drosera

The antimicrobial activity of three different extracts (hexanic, ethyl acetate, methanol) obtained from Brazilian Drosera species (D. communis, D. montana var. montana, D. brevifolia, D. villosa var. graomogolensis, D. villosa var. villosa, Drosera sp. 1, and Drosera sp. 2 ) were tested against Staphylococcus aureus (ATCC 25923), Enterococcus faecium (ATCC23212), Pseudomonas aeruginosa (ATCC27853), Escherichia coli (ATCC11229), Salmonella choleraesuis (ATCC10708), Klebsiella pneumoniae (ATCC13883), and Candida albicans (a human isolate). Better antimicrobial activity was observed with D. communis and D. montana var. montana ethyl acetate extracts. Phytochemical analyses from D. communis, D. montana var. montana and D. brevifolia yielded 5-hydroxy-2-methyl-1,4-naphthoquinone (plumbagin); long chain aliphatic hydrocarbons were isolated from D. communis and from D. villosa var. villosa, a mixture of long chain aliphatic alcohols and carboxylic acids, was isolated from D. communis and 3b-O-acetylaleuritolic acid from D. villosa var. villosa