A Merger Scenario for the Dynamics of Abell 665

We present new redshift measurements for 55 galaxies in the vicinity of the rich galaxy cluster Abell 665. When combined with results from the literature, we have good velocity measurements for a sample of 77 confirmed cluster members from which we derive the cluster's redshift z=0.1829 +/- 0.0005 and line-of-sight velocity dispersion of 1390 +/- 120 km/s. Our analysis of the kinematical and spatial data for the subset of galaxies located within the central 750 kpc reveals only subtle evidence for substructure and non-Gaussianity in the velocity distribution. We find that the brightest cluster member is not moving significantly relative to the other galaxies near the center of the cluster. On the other hand, our deep ROSAT high resolution image of A665 shows strong evidence for isophotal twisting and centroid variation, thereby confirming previous suggestions of significant substructure in the hot X-ray--emitting intracluster gas. In light of this evident substructure, we have compared the optical velocity data with N-body simulations of head-on cluster mergers. We find that a merger of two similar mass subclusters (mass ratios of 1:1 or 1:2) seen close to the time of core-crossing produces velocity distributions that are consistent with that observed.Comment: 30 pages and 7 figures. Accepted by the Astrophysical Journal Full resoultion figures 1 and 3 available in postscript at http://www.physics.rutgers.edu/~percy/A665paper.htm

Inflammasome activation during spontaneous preterm labor with intraâ amniotic infection or sterile intraâ amniotic inflammation

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/146295/1/aji13049.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/146295/2/aji13049_am.pd

The amniotic fluid cell-free transcriptome in spontaneous preterm labor

The amniotic fluid (AF) cell-free RNA was shown to reflect physiological and pathological processes in pregnancy, but its value in the prediction of spontaneous preterm delivery is unknown. Herein we profiled cell-free RNA in AF samples collected from women who underwent transabdominal amniocentesis after an episode of spontaneous preterm labor and subsequently delivered within 24 h (n = 10) or later (n = 28) in gestation. Expression of known placental single-cell RNA-Seq signatures was quantified in AF cell-free RNA and compared between the groups. Random forest models were applied to predict time-to-delivery after amniocentesis. There were 2385 genes differentially expressed in AF samples of women who delivered within 24 h of amniocentesis compared to gestational age-matched samples from women who delivered after 24 h of amniocentesis. Genes with cell-free RNA changes were associated with immune and inflammatory processes related to the onset of labor, and the expression of placental single-cell RNA-Seq signatures of immune cells was increased with imminent delivery. AF transcriptomic prediction models captured these effects and predicted delivery within 24 h of amniocentesis (AUROC = 0.81). These results may inform the development of biomarkers for spontaneous preterm birth

Composite Luminosity Functions Based on the Sloan Digital Sky Survey "Cut & Enhance" Galaxy Cluster Catalog

We present here results on the composite luminosity functions of galaxies in the clusters of galaxies selected from the SDSS Cut and Enhance cluster catalog (CE; Goto et al. 2001). We construct the composite luminosity function in the five SDSS bands, u,g,r,i and z, using 204 CE clusters ranging from z=0.02 to z=0.25. We use photometric redshifts to construct composite luminosity functions. The robustness of the weighting scheme was tested using Monte Carlo simulation. We find the slope of composite LFs become flatter toward redder color band. Comparing with field LFs of SDSS (Blanton et al. 2001), cluster LFs have brighter characteristic magnitude and flatter slopes in g, r, i and z bands. These results are consistent with the hypothesis that the cluster LF has two distinct underlying populations i.e. the bright end of the LF is dominated by bright early types that follow a gaussian--like luminosity distribution, while the faint--end of the cluster LF is a steep power--law like function dominated by star--forming (bluer) galaxies. We also study the composite luminosity functions for early--type and late--type galaxies using profile fits, a concentration parameter and u-r color to classify galaxy morphology. The strong dependence of LF on galaxy morphology is found.The faint end slope of the LF is always flatter for early--type galaxies than late--type regardless of passband and methodology. These results are consistent with the hypothesis that the cluster region are dominated by bright elliptical galaxies.Comment: 21 pages, 5 figures, PASJ, 54, 515, miner typos fixe

The cytokine network in women with an asymptomatic short cervix and the risk of preterm delivery

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/138402/1/aji12686_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/138402/2/aji12686.pd

Disorders of placental villous maturation are present in one-third of cases with spontaneous preterm labor

Spontaneous preterm labor is an obstetrical syndrome accounting for approximately 65-70% of preterm births, the latter being the most frequent cause of neonatal death and the second most frequent cause of death in children less than five years of age worldwide. The purpose of this study was to determine and compare to uncomplicated pregnancies (1) the frequency of placental disorders of villous maturation in spontaneous preterm labor; (2) the frequency of other placental morphologic characteristics associated with the preterm labor syndrome; and (3) the distribution of these lesions according to gestational age at delivery and their severity. A case-control study of singleton pregnant women was conducted that included (1) uncomplicated pregnancies (controls, n=944) and (2) pregnancies with spontaneous preterm labor (cases, n=438). All placentas underwent histopathologic examination. Patients with chronic maternal diseases (e.g., chronic hypertension, diabetes mellitus, renal disease, thyroid disease, asthma, autoimmune disease, and coagulopathies), fetal malformations, chromosomal abnormalities, multifetal gestation, preeclampsia, eclampsia, preterm prelabor rupture of the fetal membranes, gestational hypertension, gestational diabetes mellitus, and HELLP (hemolysis, elevated liver enzymes and low platelet count) syndrome were excluded from the study. Compared to the controls, the most prevalent placental lesions among the cases were the disorders of villous maturation (31.8% [106/333] including delayed villous maturation 18.6% [62/333] vs. 1.4% [6/442], q\u3c0.0001, prevalence ratio 13.7; and accelerated villous maturation 13.2% [44/333] vs. 0% [0/442], q\u3c0.001). Other lesions in decreasing order of prevalence included hypercapillarized villi (15.6% [68/435] vs. 3.5% [33/938], q\u3c0.001, prevalence ratio 4.4); nucleated red blood cells (1.1% [5/437] vs. 0% [0/938], q\u3c0.01); chronic inflammatory lesions (47.9% [210/438] vs. 29.9% [282/944], q\u3c0.0001, prevalence ratio 1.6); fetal inflammatory response (30.1% [132/438] vs. 23.2% [219/944], q\u3c0.05, prevalence ratio 1.3); maternal inflammatory response (45.5% [195/438] vs. 36.1% [341/944], q\u3c0.01, prevalence ratio 1.2); and maternal vascular malperfusion (44.5% [195/438] vs. 35.7% [337/944], q\u3c0.01, prevalence ratio 1.2). Accelerated villous maturation did not show gestational age-dependent association with any other placental lesion while delayed villous maturation showed a gestational age-dependent association with acute placental inflammation (q-value=0.005). Disorders of villous maturation are present in nearly one-third of the cases of spontaneous preterm labor

The Environment of Passive Spiral Galaxies in the SDSS

In previous work on galaxy clusters, several authors reported a discovery of an unusual population of galaxies, which have spiral morphologies, but do not show any star formation activity. These galaxies are called ``passive spirals'', and have been interesting since it has been difficult to understand the existence of such galaxies. Using a volume limited sample (0.05<z<0.1 and Mr<-20.5; 25813 galaxies) of the Sloan Digital Sky Survey data, we have found 73 (0.28$\pm$0.03%) passive spiral galaxies and studied their environments. It is found that passive spiral galaxies live in local galaxy density 1-2 Mpc$^{-2}$ and 1-10 cluster-centric virial radius. Thus the origins of passive spiral galaxies are likely to be cluster related. These characteristic environments coincide with the previously reported environment where galaxy star formation rate suddenly declines and the so-called morphology-density relation turns. It is likely that the same physical mechanism is responsible for all of these observational results. The existence of passive spiral galaxies suggests that a physical mechanism that works calmly is preferred to dynamical origins such as major merger/interaction since such a mechanism can destroy spiral arm structures. Compared with observed cluster galaxy evolution such as the Butcher-Oemler effect and the morphological Butcher-Oemler effect, passive spiral galaxies are likely to be a galaxy population in transition between red, elliptical/S0 galaxies in low redshift clusters and blue, spiral galaxies more numerous in higher redshift clusters.Comment: 31 pages, 13 figures, PASJ in pres

Catalog of Galactic Beta Cephei Stars

We present an extensive and up-to-date catalog of Galactic Beta Cephei stars. This catalog is intended to give a comprehensive overview of observational characteristics of all known Beta Cephei stars. 93 stars could be confirmed to be Beta Cephei stars. For some stars we re-analyzed published data or conducted our own analyses. 61 stars were rejected from the final Beta Cephei list, and 77 stars are suspected to be Beta Cephei stars. A list of critically selected pulsation frequencies for confirmed Beta Cephei stars is also presented. We analyze the Beta Cephei stars as a group, such as the distributions of their spectral types, projected rotational velocities, radial velocities, pulsation periods, and Galactic coordinates. We confirm that the majority of these stars are multiperiodic pulsators. We show that, besides two exceptions, the Beta Cephei stars with high pulsation amplitudes are slow rotators. We construct a theoretical HR diagram that suggests that almost all 93 Beta Cephei stars are MS objects. We discuss the observational boundaries of Beta Cephei pulsation and their physical parameters. We corroborate that the excited pulsation modes are near to the radial fundamental mode in frequency and we show that the mass distribution of the stars peaks at 12 solar masses. We point out that the theoretical instability strip of the Beta Cephei stars is filled neither at the cool nor at the hot end and attempt to explain this observation