Direct transformation of-alkane into all-conjugated polyene via cascade dehydrogenation

Selective C(sp$^{3}$) −H activation is of fundamental importance in processing alkane feedstocks to produce high-value-added chemical products. By virtue of an on-surface synthesis strategy, we report selective cascade dehydrogenation of n-alkane molecules under surface constraints, which yields monodispersed all-trans conjugated polyenes with unprecedented length controllability. We are also able to demonstrate the generality of this concept for alkyl-substituted molecules with programmable lengths and diverse functionalities, and more importantly its promising potential in molecular wiring

Ultrasonography Monitoring of Trauma-Induced Heterotopic Ossification: Guidance for Rehabilitation Procedures

Traumatic injury is one of varying causes of heterotopic ossification (HO). After HO occurrence, rehabilitation training need alterations to avoid the aggravation of HO. Therefore, monitoring of HO development plays an important role in the rehabilitation procedure. The aims of this study are to evaluate the post-traumatic HO occurring at various joints, to describe the features of HO development in ultrasound images, and to provide a guidance for the orthopedist to make individualized rehabilitation therapy. Eight subjects with the post-traumatic HO were recruited in this study. The joints on the injured side was examined by plain radiography. The joints on the injured side and the corresponding sites on the uninjured sides were scanned by ultrsonography. The HO tissues were segmented automatically using a semi-supervised segmentation algorithm. Then the HO tissues were evaluated in comparison with the corresponding region of the uninjured side. During the development stage of immature HO, ultrasonography was sensitive to observe the involved soft tissue and the calcification of HO. The characteristics of HO tissues in ultrasound image included the hyperechoic mass occasionally accompanied with acoustic shadow and the irregular muscular architecture. It was found that the mean grayscale value of HO was significantly higher (p < 0.001) than that of the uninjured side at the middle and late stages. During the development period of HO, the HO grayscale value gradually increased and the mean grayscale of value of mature HO was significantly higher (p < 0.05) than that of immature HO. According to the information of HO provided by ultrasound, the orthopedist properly adjusted the rehabilitation treatment. The results demonstrated that the visualization of HO using ultrasonography revealed the development of HO in the muscle tissues around the injured joints and thus provide a guidance for the orthopedist to make individualized rehabilitation therapy. Ultrasound could be a useful imaging modality for quantitative evaluation of HO during the rehabilitation of traumatic injury

Dirac Fermions in Antiferromagnetic FeSn Kagome Lattices with Combined Space Inversion and Time Reversal Symmetry

Symmetry principles play a critical role in formulating the fundamental laws of nature, with a large number of symmetry-protected topological states identified in recent studies of quantum materials. As compelling examples, massless Dirac fermions are jointly protected by the space inversion symmetry $P$ and time reversal symmetry $T$ supplemented by additional crystalline symmetry, while evolving into Weyl fermions when either $P$ or $T$ is broken. Here, based on first-principles calculations, we reveal that massless Dirac fermions are present in a layered FeSn crystal containing antiferromagnetically coupled ferromagnetic Fe kagome layers, where each of the $P$ and $T$ symmetries is individually broken but the combined $PT$ symmetry is preserved. These stable Dirac fermions protected by the combined $PT$ symmetry with additional non-symmorphic $S_{\rm{2z}}$ symmetry can be transformed to either massless/massive Weyl or massive Dirac fermions by breaking the $PT$ or $S_{\rm{2z}}$ symmetry. Our angle-resolved photoemission spectroscopy experiments indeed observed the Dirac states in the bulk and two-dimensional Weyl-like states at the surface. The present study substantially enriches our fundamental understanding of the intricate connections between symmetries and topologies of matter, especially with the spin degree of freedom playing a vital role.Comment: 6 pages, 4 figure

AdaBoost.Rt-LSTM Based Joint SOC and SOH Estimation Method for Retired Batteries

Achieving accurate retired battery state of health (SOH) and state of charge (SOC) estimation is a safe prerequisite for securing the battery secondary utilization and thus effectively improving the energy utilization efficiency. The data-driven approach is efficient and accurate, and does not rely on accurate battery models, which is a hot direction in battery state estimation research. However, the huge number of retired batteries and obvious consistency differences bring bottleneck problems such as long learning time and low model updating efficiency to the traditional data-driven algorithm. In view of this, this paper proposes an integrated learning algorithm based on AdaBoost. Rt-LSTM to realize the joint estimation of SOC and SOH of retired lithium batteries, which relies on the LSTM neural network model and completes the correlation adaption in the spatio-temporal dimension of the whole life cycle sample data. The LSTM model is used as the base learner to construct the AdaBoost. Rt-LSTM strong learning model. The LSTM weak predictor is combined with weights to form a strong predictor, which greatly solves the problem of low accuracy of state estimation due to the large number and variability of retired batteries. Simulation and experimental comparison show that the integrated algorithm proposed in this paper is suitable for improving the SOC and SOH prediction accuracy and the generalization performance of the model

Updating Insights into the Regulatory Mechanisms of Calcineurin-Activated Transcription Factor Crz1 in Pathogenic Fungi

Ca2+, as a second messenger in cells, enables organisms to adapt to different environmental stresses by rapidly sensing and responding to external stimuli. In recent years, the Ca2+ mediated calcium signaling pathway has been studied systematically in various mammals and fungi, indicating that the pathway is conserved among organisms. The pathway consists mainly of complex Ca2+ channel proteins, calcium pumps, Ca2+ transporters and many related proteins. Crz1, a transcription factor downstream of the calcium signaling pathway, participates in regulating cell survival, ion homeostasis, infection structure development, cell wall integrity and virulence. This review briefly summarizes the Ca2+ mediated calcium signaling pathway and regulatory roles in plant pathogenic fungi. Based on discussing the structure and localization of transcription factor Crz1, we focus on the regulatory role of Crz1 on growth and development, stress response, pathogenicity of pathogenic fungi and its regulatory mechanisms. Furthermore, we explore the cross-talk between Crz1 and other signaling pathways. Combined with the important role and pathogenic mechanism of Crz1 in fungi, the new strategies in which Crz1 may be used as a target to explore disease control in practice are also discussed