Endothelial nitric oxide synthase gene polymorphisms associated with periodontal diseases in Turkish adults

Endothelial nitric oxide synthase (NOS3) is involved in key steps of immune response. Genetic factors predispose individuals to periodontal disease. This study's aim was to explore the association between NOS3 gene polymorphisms and clinical parameters in patients with periodontal disease. Genomic DNA was obtained from the peripheral blood of 23 subjects with aggressive periodontitis (AgP), 26 with chronic periodontitis (CP), 31 with gingivitis (G) and 50 healthy controls. Probing depth (PD), clinical attachment loss (CAL), plaque index (PI) and gingival index (GI) were recorded as clinical parameters. We genotyped NOS3 polymorphisms using the PCR and/or PCR-RFLP method. Genotype frequencies differed significantly among periodontal diseases and controls for these polymorphisms. A significant association was detected between NOS3 +894 polymorphism and PD and CAL in the CP and AgP patient groups; whereas NOS VNTR analysis detected no associations with clinical parameters in theCP and AgP groups. However, a significant association was detected between the AA genotype and both PI and GI in patients with gingivitis; and a significant association was shown between the BB genotype and PI. The present study shows that two common polymorphisms of the NOS3 gene cluster are significantly associated with the occurrence of periodontal diseases

Lacunary statistical cluster points of sequences

In this note we introduce the concept of a lacunary statistical cluster (l.s.c.) point and prove some of its properties in finite dimensional Banach spaces. We develop the method suggested by S. Pehlivan and M.A. Mamedov [20] where it was proved that under some conditions optimal paths have the same unique stationary limit point and stationary cluster point. We also show that the set $Gamma_x^{theta}$ of l.s.c. points is nonempty and compact

Invariants of Collective Neutrino Oscillations

We consider the flavor evolution of a dense neutrino gas by taking into account both vacuum oscillations and self interactions of neutrinos. We examine the system from a many-body perspective as well as from the point of view of an effective one-body description formulated in terms of the neutrino polarization vectors. We show that, in the single angle approximation, both the many-body picture and the effective one-particle picture possess several constants of motion. We write down these constants of motion explicitly in terms of the neutrino isospin operators for the many-body case and in terms of the polarization vectors for the effective one-body case. The existence of these constants of motion is a direct consequence of the fact that the collective neutrino oscillation Hamiltonian belongs to the class of Gaudin Hamiltonians. This class of Hamiltonians also includes the (reduced) BCS pairing Hamiltonian describing superconductivity. We point out the similarity between the collective neutrino oscillation Hamiltonian and the BCS pairing Hamiltonian. The constants of motion manifest the exact solvability of the system. Borrowing the well established techniques of calculating the exact BCS spectrum, we present exact eigenstates and eigenvalues of both the many-body and the effective one-particle Hamiltonians describing the collective neutrino oscillations. For the effective one-body case, we show that spectral splits of neutrinos can be understood in terms of the adiabatic evolution of some quasi-particle degrees of freedom from a high density region where they coincide with flavor eigenstates to the vacuum where they coincide with mass eigenstates. We write down the most general consistency equations which should be satisfied by the effective one-body eigenstates and show that they reduce to the spectral split consistency equations for the appropriate initial conditions.Comment: 26 pages with one figure. Published versio

Lacunary statistical cluster points of sequences

In this note we introduce the concept of a lacunary statistical cluster (l.s.c.) point and prove some of its properties in finite dimensional Banach spaces. We develop the method suggested by S. Pehlivan and M.A. Mamedov [20] where it was proved that under some conditions optimal paths have the same unique stationary limit point and stationary cluster point. We also show that the set $Gamma_x^{theta}$ of l.s.c. points is nonempty and compact

Thalassemia mutations in Gaziantep, Turkey

Ninety-eight postnatal and six prenatal cases of thalassemia were studied by the reverse dot-blot hybridization technique in the city of Gaziantep, Turkey. We found the following mutations: IVS 1.110 (G>A) in 29.1%, IVS 2.1 (G>A) in 12.3%, IVS 1.1 (G>A) in 7.7%, Codon 8 (-AA) in 5.6%, -30 (T>A) in 4.6%, IVS 1.6 (T>C) in 4.6%, Codon 39 (C>T) in 3.6%, Codon 44 (-C) in 3.1%, IVS 2.745 (C>G) in 1.5%, Codon 8/9 (+G) in 2.1%, Codon 36/37 (-T) in 2.1%, IVS 1.5 (G>C) in 2.1%, Codon 22 (7pb del) in 0.5%, Codon 5 (-CT) in 0.5% while 20.9% were undetermined. 54 of the thalassemia patients were homozygotes, 12 were compound heterozygous and 31 were heterozygotes. In one allele of 5 thalassemia patients, - thalassemia mutation (3.7 single gene deletions in 1 patient, anti-3.7 gene triplication in 4 patients) wasdetermined at the same time. Finally, this is the first comprehensive study in this region and percentage of and - globin genes mutation is 2.6 and 79.4%, respectively

Chromium toxicity in Moringa oleifera Lam.

This study investigated the toxic effects of different Cr concentrations (Control, 5, 25 and 50 mg/L) on hydroponically cultivated M. oleifera seedlings. At the end of the application, certain biochemical variations and changes in Cr and nutrient content (K, Zn, Ca, Cu, Fe, Mg and Mn) of the plant roots and shoots were determined. M. oleifera seedlings accumulated high Cr concentrations in roots and shoots. As a result, Cr led to nutrient deficiency by affecting the intake and transportation of the necessary macro and micro elements. Increase in phenolic compound content and non-protein SH groups may indicate that they played a role in Cr toxicity. Furthermore, the increases in H2O2 and MDA levels clearly demonstrated that Cr toxicity induced oxidative stress in M. oleifera cells

Chromium toxicity in Moringa oleifera Lam.

537-543This study investigated the toxic effects of different Cr concentrations (Control, 5, 25 and 50 mg/L) on hydroponically cultivated M. oleifera seedlings. At the end of the application, certain biochemical variations and changes in Cr and nutrient content (K, Zn, Ca, Cu, Fe, Mg and Mn) of the plant roots and shoots were determined. M. oleifera seedlings accumulated high Cr concentrations in roots and shoots. As a result, Cr led to nutrient deficiency by affecting the intake and transportation of the necessary macro and micro elements. Increase in phenolic compound content and non-protein SH groups may indicate that they played a role in Cr toxicity. Furthermore, the increases in H2O2 and MDA levels clearly demonstrated that Cr toxicity induced oxidative stress in M. oleifera cells

Spectra and Symmetry in Nuclear Pairing

We apply the algebraic Bethe ansatz technique to the nuclear pairing problem with orbit dependent coupling constants and degenerate single particle energy levels. We find the exact energies and eigenstates. We show that for a given shell, there are degeneracies between the states corresponding to less and more than half full shell. We also provide a technique to solve the equations of Bethe ansatz.Comment: 15 pages of REVTEX with 2 eps figure

Exactly Solvable Pairing Model Using an Extension of Richardson-Gaudin Approach

We introduce a new class of exactly solvable boson pairing models using the technique of Richardson and Gaudin. Analytical expressions for all energy eigenvalues and first few energy eigenstates are given. In addition, another solution to Gaudin's equation is also mentioned. A relation with the Calogero-Sutherland model is suggested.Comment: 9 pages of Latex. In the proceedings of Blueprints for the Nucleus: From First Principles to Collective Motion: A Festschrift in Honor of Professor Bruce Barrett, Istanbul, Turkey, 17-23 May 200

Interpolation of SUSY quantum mechanics

Interpolation of two adjacent Hamiltonians in SUSY quantum mechanics $H_s=(1-s)A^{\dagger}A + sAA^{\dagger}$, $0\le s\le 1$ is discussed together with related operators. For a wide variety of shape-invariant degree one quantum mechanics and their `discrete' counterparts, the interpolation Hamiltonian is also shape-invariant, that is it takes the same form as the original Hamiltonian with shifted coupling constant(s).Comment: 18 page