ANTI-HYPERGLYCEMIC EFFECT OF HYDRO-ALCOHOLIC EXTRACT OF THUNBERGIA FRAGRANS IN EXPERIMENTAL DIABETES

Objective: The aim of present research was undertaken to find out the effect of the potential Antidiabetic activity of Thunbergiafragrans and their effects on key metabolic enzymes involved in carbohydrate metabolism on alloxan induced diabetes in wistar rats. Methods: In this study the plant extract was taken and measuring the changes in Blood glucose, Body weight, Glycogen content, Hematological & biochemical parameters, Hepatic glucokinase& hexokinase activity, and Glucose-6-phosphate levels inalloxan-induced diabetic rats. Results: The effects produced by this plant extract on different parameters were compared with glipizide. Conclusion: This extract also showed improvement in the parameters like body weight, liver glycogen content and carbohydrate metabolizing enzymes, as well as regeneration of β-cells of pancreas and so might be of value in diabetes treatmen

Accomplishments and challenges in tobacco control endeavors – report from the Gulf Cooperation Council countries

© 2017 The Authors Objectives To review the tobacco governance and national responsibility for control, and existing countering measures to reduce the tobacco use among the Gulf Cooperation Council (GCC) member states. Methods We reviewed the data in regards to tobacco control efforts and difficulties encountered during implementation of the policies for all the GCC member states from the respective country profile in the WHO report on the global tobacco epidemic. Also, we utilized the measures outlined in the FCTC\u27s MPOWER package to not only assess the degree of national commitment, but also compare it against the level of significance that the legislatures give to this matter. Results We observed that there have been genuine advancements towards tobacco control in the GCC member states over the past few years. All the countries except Bahrain have national offices committed to tobacco control and 5 nations (excluding Oman) have dedicated support services for smoking cessation accessible to the general public. Similarly, majority of the member states have implemented a national-level ban on tobacco advertisement through national media cells as well as free dissemination of marketing material. Conclusion Application and implementation of measures outline in the MPOWER package, formulation and enforcement of sturdy laws on tobacco control, and development of infrastructure and trained workforce are fundamental to manage and reinforce tobacco control measures in the GCC region