138 research outputs found

    Revue des methodes diagnostiques en allergie. [Review of diagnostic methods in allergy]

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    To investigate the possible role of allergy in asthma or chronic rhinitis, four groups of tests can be used. The patient's history, which is the best way to determine the severity of the disease and the clinical relevance of the allergens detected by other diagnostic means. Tests which disclose an atopic constitution. The predictive value of the serum level of total IgE is somewhat lessened by 20-30% false positive and false negative results. Phadiatop, introduced in 1986, appears to be a more accurate screening test for respiratory allergy. Tests which disclose the presence of allergen-specific IgE, in the skin (skin tests) or in serum (RAST). Tests which reproduce the allergic disease in the shock organ (conjunctival, nasal and bronchial provocation tests). These tests are used in clinical research rather than in the routine diagnosis of allergy

    La desensibilisation allergique: revue des essais cliniques controles. [Allergic desensitization: review of controlled clinical trials]

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    Allergic desensitization is still a subject of controversy. Several controlled studies have demonstrated its efficacy in allergy to hymenoptera venoms and in hayfever; results obtained in hypersensitivity to house dust mites, animal danders and molds are still controversial and those obtained with mixtures of various allergens and bacterial extracts have been most often negative. In the 80's, a new type of allergen preparation has become available in which the allergen content (and not only the protein content) is well determined ("standardized extract"). The use of this new type of preparation should allow a better quantitative approach to allergologic investigations, which are very useful for assessment of the desensitization value
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