Economic Change and Change in Well-Being in the Czech Republic, with Comparisons to Married Women in the United States

Examines the effects of economic change on individual well-being for a panel of married Czech women compared with a US sample from IA (N = 192 & 386, respectively, in 1990/91). Questionnaire data show that respondents who were forced to make economic adjustments reducing their standard of living also reported increased health problems & depressive symptoms. Contrary to some US findings the relationship between economic adjustments & change in depressive symptoms was strongest among those who reported having the strongest sense of personal control (mastery) & the highest perceived social support. Compared with the US sample, married Czech women reported more depressive symptoms, had more health problems, & were lower in feelings of mastery. In addition, Czech women recorded significantly stronger paths linking education to changes in health conditions & depressive symptoms, whereas US women had significantly stronger paths linking actual economic conditions to subsequent economic adjustments. Data suggest that the US stress-distress model applies in the Czech Republic as well, but further understanding of the differentiated role of social support & mastery for Czech & US women is necessray to more completely interpret the observed interactions

Tumour volume and radiotherapy prolongation in locally advanced head and neck cancer patients treated with radical IMRT

Aims. The relationship of tumour volume, radiotherapy treatment time and other prognostic factors affecting prognosis was evaluated. Methods. 184 patients with locally advanced head and neck cancer were treated with radical intensity modulated radiotherapy (IMRT) and compared retrospectively. Results. In the multivariate analysis the overall survival was dependent on gross tumour volume (GTV), clinical stage (CS), radiotherapy treatment time (RTT) and p16 status. Local control was influenced by GTV, overall RTT and age. DFS was significantly affected by GTV, CS, RTT, p16 status and concomitant chemotherapy (CHT). Conclusions. The tumour volume and the radiotherapy treatment time were the most significant prognostic factors with the best outcomes in patients with GTV ≤ 55 cc and RTT ≤ 48 days (mean LC 8.1, DFS 7.1 and OS 6.4 years) and worst outcomes with GTV > 55 cc and RTT >48 days (mean LC 4.4, mean DFS 3.2 and mean OS 2.6 years)