19,218 research outputs found
Erosion-corrosion behaviour of Zirconia WC-6Co, WC-6Ni and SS316
The current study investigates a ceramic, two cermets and a metal under solid-liquid impingement with 3.5% NaCl and 150mg/l hydraulic fracturing sand at two extreme angles of impact, 90° and 20°. The materials tested were Zirconia, sintered WC-6Co, sintered WC-6Ni and SS316. Each material was exposed to a testing regime using re-circulating impinging jet apparatus with a velocity of 19m/s and one hour duration. The electrochemical properties of the materials were investigated in-situ through anodic and cathodic polarisation and application of cathodic protection. Post experimental analysis of the degraded surface was completed using Scanning Electron Microscopy (SEM) and Optical 3D Imaging. Zirconia exhibited a brittle response to erosion-corrosion testing with the mass loss at 90° being fifty times greater than the negligible mass loss at 20°. WC-6Co and WC-6Ni both outperformed SS316 under all solid-liquid impingement erosion-corrosion testing regimes. WC-6Ni exhibited slightly better erosion-corrosion resistance over WC-6Co at both 90° and 20°. SS316 had the best corrosion resistance and showed passivation during anodic polarisations in solid-liquid impingement conditions. The nickel binder increased the corrosion resistance of WC-6Ni over WC-6Co. Cathodic protection was successfully applied on sintered WC-6Co and SS316 isolating the key components of erosion-corrosion
Further explorations of Skyrme-Hartree-Fock-Bogoliubov mass formulas. XI: Stabilizing neutron stars against a ferromagnetic collapse
We construct a new Hartree-Fock-Bogoliubov (HFB) mass model, labeled HFB-18,
with a generalized Skyrme force. The additional terms that we have introduced
into the force are density-dependent generalizations of the usual and
terms, and are chosen in such a way as to avoid the high-density
ferromagnetic instability of neutron stars that is a general feature of
conventional Skyrme forces, and in particular of the Skyrme forces underlying
all the HFB mass models that we have developed in the past. The remaining
parameters of the model are then fitted to essentially all the available mass
data, an rms deviation of 0.585 MeV being obtained. The new model thus
gives almost as good a mass fit as our best-fit model HFB-17 ( = 0.581
MeV), and has the advantage of avoiding the ferromagnetic collapse of neutron
stars.Comment: accepted for publication in Physical Review
Symmetry energy: nuclear masses and neutron stars
We describe the main features of our most recent Hartree-Fock-Bogoliubov
nuclear mass models, based on 16-parameter generalized Skyrme forces. They have
been fitted to the data of the 2012 Atomic Mass Evaluation, and favour a value
of 30 MeV for the symmetry coefficient J, the corresponding root-mean square
deviation being 0.549 MeV. We find that this conclusion is compatible with
measurements of neutron-skin thickness. By constraining the underlying
interactions to fit various equations of state of neutron matter calculated
{\it ab initio} our models are well adapted to a realistic and unified
treatment of all regions of neutron stars. We use our models to calculate the
composition, the equation of state, the mass-radius relation and the maximum
mass. Comparison with observations of neutron stars again favours a value of J
= 30 MeV.Comment: 10 pages, 9 figures, to appear in EPJA special volume on symmetry
energ
Giant Pulsar Glitches and the Inertia of Neutron-Star Crusts
Giant pulsar frequency glitches as detected in the emblematic Vela pulsar
have long been thought to be the manifestation of a neutron superfluid
permeating the inner crust of a neutron star. However, this superfluid has been
recently found to be entrained by the crust, and as a consequence it does not
carry enough angular momentum to explain giant glitches. The extent to which
pulsar-timing observations can be reconciled with the standard vortex-mediated
glitch theory is studied considering the current uncertainties on dense-matter
properties. To this end, the crustal moment of inertia of glitching pulsars is
calculated employing a series of different unified dense-matter equations of
state.Comment: 11 pages, 6 figures, submitted to PR
Targeting tumor multicellular aggregation through IGPR-1 inhibits colon cancer growth and improves chemotherapy
Adhesion to extracellular matrix (ECM) is crucially important for survival of normal epithelial cells as detachment from ECM triggers specific apoptosis known as anoikis. As tumor cells lose the requirement for anchorage to ECM, they rely on cell-cell adhesion 'multicellular aggregation' for survival. Multicellular aggregation of tumor cells also significantly determines the sensitivity of tumor cells to the cytotoxic effects of chemotherapeutics. In this report, we demonstrate that expression of immunoglobulin containing and proline-rich receptor-1 (IGPR-1) is upregulated in human primary colon cancer. Our study demonstrates that IGPR-1 promotes tumor multicellular aggregation, and interfering with its adhesive function inhibits multicellular aggregation and, increases cell death. IGPR-1 supports colon carcinoma tumor xenograft growth in mouse, and inhibiting its activity by shRNA or blocking antibody inhibits tumor growth. More importantly, IGPR-1 regulates sensitivity of tumor cells to the chemotherapeutic agent, doxorubicin/adriamycin by a mechanism that involves doxorubicin-induced AKT activation and phosphorylation of IGPR-1 at Ser220. Our findings offer novel insight into IGPR-1's role in colorectal tumor growth, tumor chemosensitivity, and as a possible novel anti-cancer target.Grant support from: R01 CA175382/CA/NCI NIH HHS/United States, R21 CA191970/CA/NCI NIH HHS/United States, and R21 CA193958/CA/NCI NIH HHS/United State
A revised tropical to subtropical paleogene planktonic foraminiferal zonation
Author Posting. © Cushman Foundation for Foraminiferal Research, 2005. This article is posted here by permission of Cushman Foundation for Foraminiferal Research for personal use, not for redistribution. The definitive version was published in Journal of Foraminiferal Research 35 (2005): 279-298, doi:10.2113/35.4.279.New biostratigraphic investigations on deep sea cores and outcrop sections have revealed several shortcomings in currently used tropical to subtropical Eocene planktonic foraminiferal zonal schemes in the form of: 1) modified taxonomic concepts, 2) modified/different ranges of taxa, and 3) improved calibrations with magnetostratigraphy. This new information provides us with an opportunity to make some necessary improvements to existing Eocene biostratigraphic schemes. At the same time, we provide an alphanumeric notation for Paleogene zones using the prefix ‘P’ (for Paleocene), ‘E’ (for Eocene) and ‘O’ (for Oligocene) to achieve consistency with recent short-hand notation for other Cenozoic zones (Miocene [’M’], Pliocene [PL] and Pleistocene [PT]).
Sixteen Eocene (E) zones are introduced (or nomenclaturally emended) to replace the 13 zones and subzones of Berggren and others (1995). This new zonation serves as a template for the taxonomic and phylogenetic studies in the forthcoming Atlas of Eocene Planktonic Foraminifera (Pearson and others, in press). The 10 zones and subzones of the Paleocene (Berggren and others, 1995) are retained and renamed and/or emended to reflect improved taxonomy and an updated chronologic calibration to the Global Polarity Time Scale (GPTS) (Berggren and others, 2000). The Paleocene/Eocene boundary is correlated with the lowest occurrence (LO) of Acarinina sibaiyaensis (base of Zone E1), at the top of the truncated and redefined (former) Zone P5.
The five-fold zonation of the Oligocene (Berggren and others, 1995) is modified to a six-fold zonation with the elevation of (former) Subzones P21a and P21b to zonal status. The Oligocene (O) zonal components are renamed and/or nomenclaturally emended
The "zeroth law" of turbulence: Isotropic turbulence simulations revisited
The dimensionless kinetic energy dissipation rate C_epsilon is estimated from
numerical simulations of statistically stationary isotropic box turbulence that
is slightly compressible. The Taylor microscale Reynolds number Re_lambda range
is 20 < Re_lambda < 220 and the statistical stationarity is achieved with a
random phase forcing method. The strong Re_lambda dependence of C_epsilon
abates when Re_lambda approx. 100 after which C_epsilon slowly approaches
approx 0.5 a value slightly different to previously reported simulations but in
good agreement with experimental results. If C_epsilon is estimated at a
specific time step from the time series of the quantities involved it is
necessary to account for the time lag between energy injection and energy
dissipation. Also, the resulting value can differ from the ensemble averaged
value by up to +-30%. This may explain the spread in results from previously
published estimates of C_epsilon.Comment: 7 pages, 7 figures. Submitted to Phys. Rev.
Key dating features for timber-framed dwellings in Surrey
This article is made available through the Brunel Open Access Publishing Fund. Copyright @ The Vernacular Architecture Group 2013. MORE OpenChoice articles are open access and distributed under the terms of the Creative Commons Attribution License 3.0.The main component of the Surrey Dendrochronology Project is the accurate dating of 177 ‘dwellings’, nearly all by tree-ring analysis. The dates are used to establish date ranges for 52 ‘key features’, which cover many aspects of timber-framing from building type to details of carpentry. It is shown that changes of method and fashion were in many cases surprisingly rapid, almost abrupt in historical terms. Previous dating criteria for timber-framed dwellings in the county have been refined and new criteria introduced. Clusters of change from the 1440s and the 1540s are shown and some possible historical links suggested.The Heritage Lottery Fund, the Domestic Buildings Research Group (Surrey), the Surrey Archaeological Society and the historical societies of Charlwood, Farnham and Nutfield
The energy requirement of farming in New Zealand
This report presents the findings of a study of the direct and indirect energy use by the New Zealand farming sector on a 'to-farm-gate' basis. Although detailed statistics are available on this sector in financial terms, little data has been collected on
inputs to agriculture in physical terms, and this complicates the application of energy analysis. This report therefore provides complete detail on all working calculations and the assumptions made, so that through wide distribution of these findings and the
resulting feedback, the study estimates may be more precisely defined and the resulting energy requirement data improved
Pressure Induced Changes in the Antiferromagnetic Superconductor YbPd2Sn
Low temperature ac magnetic susceptibility measurements of the coexistent
antiferromagnetic superconductor YbPd2Sn have been made in hydrostatic
pressures < 74 kbar in moissanite anvil cells. The superconducting transition
temperature is forced to T(SC) = 0 K at a pressure of 58 kbar. The initial
suppression of the superconducting transition temperature is corroborated by
lower hydrostatic pressure (p < 16 kbar) four point resisitivity measurements,
made in a piston cylinder pressure cell. At ambient pressure, in a modest
magnetic field of ~ 500 G, this compound displays reentrant superconducting
behaviour. This reentrant superconductivity is suppressed to lower temperature
and lower magnetic field as pressure is increased. The antiferromagnetic
ordering temperature, which was measured at T(N) = 0.12 K at ambient pressure
is enhanced, to reach T(N) = 0.58 K at p = 74 kbar. The reasons for the
coexistence of superconductivity and antiferromagnetism is discussed in the
light of these and previous findings. Also considered is why superconductivity
on the border of long range magnetic order is so much rarer in Yb compounds
than in Ce compounds. The presence of a new transition visible by ac magnetic
susceptibility under pressure and in magnetic fields greater than 1.5 kG is
suggested.Comment: 5 pages, 6 figure
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