Theoretical study of space plasmas Final report, 16 Feb. 1964 - 15 Mar. 1965

Interchange stability of Van Allen belt - Effect of resonant magnetic moment violation on trapped particles - Exact solution of universal instabilit

Theoretical studies of space plasmas Summary report, 3 May 1965 - 1 May 1966

Synchrotron radiation, ionospheric currents, auroral bombardment, and plasma instabilitie

Signaling, Resource-Based Power, and Pre-IPO Organizational Change

The theory presented suggests that underwriters are both advisors and independent agents in the issuer’s attempt to send “signals” of quality to investors by making pre-IPO organizational changes. These pre-IPO gambits are intended to increase IPO proceeds, and preemptively address potential investor concerns that would deter them from subscribing. These organizational changes initially can financially benefit founders, early investors and underwriters. But they can also have a longterm impact that some issuers, especially founders, would prefer to avoid. Utilizing signaling and resource-based power, we find that underwriter power is significantly associated with making pre-IPO gambits and lower levels of underpricing

Experimental investigation of the fundamental modes of a collisionless plasma Final report, 10 Mar. 1964 - 31 Oct. 1967

Propagation of electron cyclotron waves and effects of low frequency noise in collisionless plasm

Thyroseq V3 Molecular Profiling for Tailoring the Surgical Management of Hürthle Cell Neoplasms.

Hürthle cell predominant thyroid nodules often confound the diagnostic utility of fine needle aspiration biopsy (FNAB) with cytology often interpreted as a Hürthle cell lesion with an indeterminate risk of malignancy, Bethesda category (BC) III or IV. Molecular diagnostics for Hürthle cell predominant nodules has also been disappointing in further defining the risk of malignancy. We present a case of a slowly enlarging nodule within a goiter initially reported as benign on FNAB, BC II but on subsequent FNAB suspicious for a Hürthle cell neoplasm, BC IV. The patient had initially requested a diagnostic lobectomy for a definitive diagnosis despite a higher risk of malignancy based on the size of the nodule \u3e 4 cm alone. To better tailor this patient\u27s treatment plan, a newer expanded gene mutation panel, ThyroSeq® v3 that includes copy number alterations (CNAs) and was recently found to have greater positive predictive value (PPV) for identifying Hürthle cell carcinoma (HCC), was performed on the FNAB material. Molecular profiling with ThyroSeq® v3 was able to predict a greater risk of carcinoma, making a more convincing argument in favor of total thyroidectomy. Surgical pathology confirmed a Hürthle cell carcinoma with 5 foci of angioinvasion and foci of capsular invasion

Reversible uncoupling of oxidative phosphorylation at low oxygen tension.

The stoichiometry of oxidative phosphorylation at low oxygen tension (

Plasma Edge Kinetic-MHD Modeling in Tokamaks Using Kepler Workflow for Code Coupling, Data Management and Visualization

A new predictive computer simulation tool targeting the development of the H-mode pedestal at the plasma edge in tokamaks and the triggering and dynamics of edge localized modes (ELMs) is presented in this report. This tool brings together, in a coordinated and effective manner, several first-principles physics simulation codes, stability analysis packages, and data processing and visualization tools. A Kepler workflow is used in order to carry out an edge plasma simulation that loosely couples the kinetic code, XGC0, with an ideal MHD linear stability analysis code, ELITE, and an extended MHD initial value code such as M3D or NIMROD. XGC0 includes the neoclassical ion-electron-neutral dynamics needed to simulate pedestal growth near the separatrix. The Kepler workflow processes the XGC0 simulation results into simple images that can be selected and displayed via the Dashboard, a monitoring tool implemented in AJAX allowing the scientist to track computational resources, examine running and archived jobs, and view key physics data, all within a standard Web browser. The XGC0 simulation is monitored for the conditions needed to trigger an ELM crash by periodically assessing the edge plasma pressure and current density profiles using the ELITE code. If an ELM crash is triggered, the Kepler workflow launches the M3D code on a moderate-size Opteron cluster to simulate the nonlinear ELM crash and to compute the relaxation of plasma profiles after the crash. This process is monitored through periodic outputs of plasma fluid quantities that are automatically visualized with AVS/Express and may be displayed on the Dashboard. Finally, the Kepler workflow archives all data outputs and processed images using HPSS, as well as provenance information about the software and hardware used to create the simulation. The complete process of preparing, executing and monitoring a coupled-code simulation of the edge pressure pedestal buildup and the ELM cycle using the Kepler scientific workflow system is described in this paper

Indecomposable K1K_1 classes on a Surface and Membrane Integrals

Let $X$ be a projective algebraic surface. We recall the $K$-group $K_{1,\mathrm{ind}}^{(2)}(X)$ of indecomposables and provide evidence that membrane integrals are sufficient to detect these indecomposable classes

Spheromak Energy Transport Studies via Neutral Beam Injection

Results from the SSPX spheromak experiment provide strong motivation to add neutral beam injection (NBI) heating. Such auxiliary heating would significantly advance the capability to study the physics of energy transport and pressure limits for the spheromak. This LDRD project develops the physics basis for using NBI to heat spheromak plasmas in SSPX. The work encompasses three activities: (1) numerical simulation to make quantitative predictions of the effect of adding beams to SSPX, (2) using the SSPX spheromak and theory/modeling to develop potential target plasmas suitable for future application of neutral beam heating, and (3) developing diagnostics to provide the measurements needed for transport calculations. These activities are reported in several publications

ITER Shape Controller and Transport Simulations

We currently use the CORSICA integrated modeling code for scenario studies for both the DIII-D and ITER experiments. In these simulations, free- or fixed-boundary equilibria are simultaneously converged with thermal evolution determined from transport models providing temperature and current density profiles. Using a combination of fixed boundary evolution followed by free-boundary calculation to determine the separatrix and coil currents. In the free-boundary calculation, we use the state-space controller representation with transport simulations to provide feedback modeling of shape, vertical stability and profile control. In addition to a tightly coupled calculation with simulator and controller imbedded inside CORSICA, we also use a remote procedure call interface to couple the CORSICA non-linear plasma simulations to the controller environments developed within the Mathworks Matlab/Simulink environment. We present transport simulations using full shape and vertical stability control with evolution of the temperature profiles to provide simulations of the ITER controller and plasma response