Clustering Analyses of 300,000 Photometrically Classified Quasars--I. Luminosity and Redshift Evolution in Quasar Bias

Using ~300,000 photometrically classified quasars, by far the largest quasar sample ever used for such analyses, we study the redshift and luminosity evolution of quasar clustering on scales of ~50 kpc/h to ~20 Mpc/h from redshifts of z~0.75 to z~2.28. We parameterize our clustering amplitudes using realistic dark matter models, and find that a LCDM power spectrum provides a superb fit to our data with a redshift-averaged quasar bias of b_Q = 2.41+/-0.08 ($P_{<\chi^2}=0.847$) for $\sigma_8=0.9$. This represents a better fit than the best-fit power-law model ($\omega = 0.0493\pm0.0064\theta^ {-0.928\pm0.055}$; $P_{<\chi^2}=0.482$). We find b_Q increases with redshift. This evolution is significant at >99.6% using our data set alone, increasing to >99.9999% if stellar contamination is not explicitly parameterized. We measure the quasar classification efficiency across our full sample as a = 95.6 +/- ^{4.4}_{1.9}%, a star-quasar separation comparable with the star-galaxy separation in many photometric studies of galaxy clustering. We derive the mean mass of the dark matter halos hosting quasars as MDMH=(5.2+/-0.6)x10^{12} M_solar/h. At z~1.9 we find a $1.5\sigma$ deviation from luminosity-independent quasar clustering; this suggests that increasing our sample size by a factor of 1.8 could begin to constrain any luminosity dependence in quasar bias at z~2. Our results agree with recent studies of quasar environments at z < 0.4, which detected little luminosity dependence to quasar clustering on proper scales >50 kpc/h. At z < 1.6, our analysis suggests that b_Q is constant with luminosity to within ~0.6, and that, for g < 21, angular quasar autocorrelation measurements are unlikely to have sufficient statistical power at z < 1.6 to detect any luminosity dependence in quasars' clustering.Comment: 13 pages, 9 figures, 2 tables; uses amulateapj; accepted to Ap

Adventures in Friedmann Cosmology: An Educationally Detailed Expansion of the Cosmological Friedmann Equations

The general relativistic cosmological Friedmann equations which describe how the scale factor of the universe evolves are expanded explicitly to include energy forms not usually seen. The evolution of the universe as predicted by the Friedmann equations when dominated by a single, isotropic, stable, static, perfect-fluid energy form is discussed for different values of its gravitational pressure to density ratio $w$. These energy forms include phantom energy ($w<-1$), cosmological constant ($w=-1$), domain walls ($w = -2/3$), cosmic strings ($w = -1/3$), normal matter ($w = 0$), radiation and relativistic matter ($w = 1/3$), and a previously little-discussed form of energy called "ultralight" ($w>1/3$). A brief history and possible futures of Friedmann universes dominated by a single energy form are discussed.Comment: 32 pages, 4 tables; modified version accepted for publication in the American Journal of Physic

Cosmic microwave background and large scale structure limits on the interaction between dark matter and baryons

We study the effect on the cosmic microwave background (CMB) anisotropy and large scale structure (LSS) power spectrum of a scattering interaction between cold dark matter and baryons. This scattering alters the CMB anisotropy and LSS spectrum through momentum transfer between the cold dark matter particles and the baryons. We find that current CMB observations can put an upper limit on the scattering cross section which is comparable with or slightly stronger than previous disk heating constraints at masses greater than 1 GeV, and much stronger at smaller masses. When large-scale structure constraints are added to the CMB limits, our constraint is more stringent than this previous limit at all masses. In particular, a dark matter-baryon scattering cross section comparable to the ``Spergel-Steinhardt'' cross section is ruled out for dark matter mass greater than 1 GeV.Comment: 8 pages, 2 figures, use RevTeX4, submitted to PRD replaced with revised versio

Circularly polarized luminescence from helically chiral N,N,O,O-boron-chelated dipyrromethenes

Helically chiral N,N,O,O-boron chelated dipyrromethenes showed solution-phase circularly polarized luminescence (CPL) in the red region of the visible spectrum (λem(max) from 621 to 663 nm). The parent dipyrromethene is desymmetrised through O chelation of boron by the 3,5-ortho-phenolic substituents, inducing a helical chirality in the fluorophore. The combination of high luminescence dissymmetry factors (|glum| up to 4.7 ×10−3) and fluorescence quantum yields (ΦF up to 0.73) gave exceptionally efficient circularly polarized red emission from these simple small organic fluorophores, enabling future application in CPL-based bioimaging

Interpretation of positive troponin results among patients with and without myocardial infarction.

Measuring cardiac troponins is integral to diagnosing acute myocardial infarction (AMI); however, troponins may be elevated without AMI, and the use of multiple different assays confounds comparisons. We considered characteristics and serial troponin values in emergency department chest pain patients with and without AMI to interpret troponin excursions. We compared serial troponin in 124 AMI and non-AMI patients from the observational Performance of Triage Cardiac Markers in the Clinical Setting (PEARL) study who presented with chest pain and had at least one troponin value exceeding the 99th percentile of normal. Because 8 assays were used during data collection, we employed a method of scaling the troponin value to the corresponding assay\u27s 99th percentile upper reference limit to standardize the results. In 81 AMI patients, 96% had elevated troponin at the first test following initial elevation, compared to 73% of the 43 non-AMI patients

Optical and Radio Properties of Extragalactic Sources Observed by the FIRST and SDSS Surveys

We discuss the optical and radio properties of 30,000 FIRST sources positionally associated with an SDSS source in 1230 deg$^2$ of sky. The majority (83%) of the FIRST sources identified with an SDSS source brighter than r=21 are optically resolved. We estimate an upper limit of 5% for the fraction of quasars with broad-band optical colors indistinguishable from those of stars. The distribution of quasars in the radio flux -- optical flux plane supports the existence of the "quasar radio-dichotomy"; 8% of all quasars with i<18.5 are radio-loud and this fraction seems independent of redshift and optical luminosity. The radio-loud quasars have a redder median color by 0.08 mag, and a 3 times larger fraction of objects with red colors. FIRST galaxies represent 5% of all SDSS galaxies with r<17.5, and 1% for r<20, and are dominated by red galaxies. Magnitude and redshift limited samples show that radio galaxies have a different optical luminosity distribution than non-radio galaxies selected by the same criteria; when galaxies are further separated by their colors, this result remains valid for both blue and red galaxies. The distributions of radio-to-optical flux ratio are similar for blue and red galaxies in redshift-limited samples; this similarity implies that the difference in their luminosity functions, and resulting selection effects, are the dominant cause for the preponderance of red radio galaxies in flux-limited samples. We confirm that the AGN-to-starburst galaxy number ratio increases with radio flux, and find that radio emission from AGNs is more concentrated than radio emission from starburst galaxies (abridged).Comment: submitted to AJ, color gif figures, PS figures available from [email protected]

The Effect of Nicotine on Reproduction and Attachment of Human Gingival Fibroblasts In Vitro

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/142127/1/jper0658.pd

Structural basis of broad SARS-CoV-2 cross-neutralization by affinity-matured public antibodies

Descendants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant now account for almost all SARS-CoV-2 infections. The Omicron variant and its sublineages have spike glycoproteins that are highly diverged from the pandemic founder and first-generation vaccine strain, resulting in significant evasion from monoclonal antibody therapeutics and vaccines. Understanding how commonly elicited antibodies can broaden to cross-neutralize escape variants is crucial. We isolate IGHV3-53, using ‘‘public’’ monoclonal antibodies (mAbs) from an individual 7 months post infection with the ancestral virus and identify antibodies that exhibit potent and broad cross-neutralization, extending to the BA.1, BA.2, and BA.4/BA.5 sublineages of Omicron. Deep mutational scanning reveals these mAbs’ high resistance to viral escape. Structural analysis via cryoelectron microscopy of a representative broadly neutralizing antibody, CAB-A17, in complex with the Omicron BA.1 spike highlights the structural underpinnings of this broad neutralization. By reintroducing somatic hypermutations into a germline-reverted CAB-A17, we delineate the role of affinity maturation in the development of cross-neutralization by a public class of antibodies

‘Paying Attention’ in a Digital Economy: Reflections on the Role of Analysis and Judgement Within Contemporary Discourses of Mindfulness and Comparisons with Classical Buddhist Accounts of Sati

This chapter examines the question of the role of intellectual analysis and ethical judgement in ancient Indian Buddhist accounts of sati and contemporary discourses about ‘mindfulness’. Attention is paid to the role of paññ? (Sanskrit: prajñ?: ‘wisdom’ or ‘analytical insight’) and ethical reflection in the cultivation of sati in mainstream Abhidharma and early Mah?y?na philosophical discussions in India, noting the existence of a subordinate strand of Buddhist thought which focuses upon the non-conceptuality of final awakening (bodhi) and the quiescence of mind. Modern discourses of mindfulness are examined in relation to detraditionalization, the global spread of capitalism and widespread adoption of new information technologies. It is argued that analysis of the exponential growth in popularity of ‘mindfulness’ techniques must be linked to an exploration of the modern history of attention, more specifically, the possibility that the use of fast-paced, digital, multimedia technologies is facilitating a demand for fragmented or dispersed attention. It is argued that the fault line between divergent contemporary accounts of mindfulness can be seen most clearly over the issue of the role of ethical judgements and mental ratiocination within mindfulness practice. The two most extreme versions on this spectrum see mindfulness on the one hand as a secular mental technology for calming the mind and reducing stress and discomfort, and on the other as a deeply ethical and experiential realization of the geopolitics of human experience. These, it is suggested, constitute an emerging discursive split in accounts of mindfulness reflective of divergent responses to the social, economic, political and technological changes occurring in relation to the global spread of neoliberal forms of capitalism

Statistical properties of the linear tidal shear

Large-scale structures originate from coherent motions induced by inhomogeneities in the primeval gravitational potential. Here, we investigate the two-point statistics of the second derivative of the potential, the tidal shear, under the assumption of Gaussianity. We derive an exact closed form expression for the angular averaged, two-point distribution of the shear components which is valid for an arbitrary Lagrangian separation. This result is used to write down the two-point statistics of the shear eigenvalues in compact form. Next, we examine the large-scale asymptotics of the correlation of the shear eigenvalues, and the alignment of the principal axes. The analytic results are in good agreement with measurements obtained from random realizations of the gravitational potential. Finally, we show that a number of two-point distributions of the shear eigenvalues are well approximated by Gaussian bivariates over a wide range of separation and smoothing scales. We speculate that the Gaussian approximation also holds for multiple point distributions of the shear eigenvalues. It is hoped that these results will be relevant for studies aimed at describing the properties of the (evolved) matter distribution in terms of the statistics of the primordial shear field.Comment: 13 pages, 6 figures. Matches version published in PR