5,591 research outputs found
Channeling of electrons and positrons in straight and periodically bent diamond(110) crystals
In this paper we present the results of a systematic numerical analysis of
the channeling properties of electrons and positrons in oriented straight and
periodically bent diamond(110) crystals. We analyse dependence of the intensity
of the radiation emitted on the projectile energy as well as on the bending
amplitude. The analysis presented is based on the grounds of accurate numerical
simulations of the channeling process. The simulation parameters, such as the
crystal orientation, thickness and bending parameters of the crystals as well
as the energy of the projectiles, were chosen to match those used in past and
ongoing experiments. The peculiarities which appear in the radiation spectra
are attributed to the interplay of various radiation mechanisms. The analysis
performed can be used to predict and explain future experimental results.Comment: 14 pages, 8 figures, 1 tabl
An Apology of Contemporary American Horror Remakes
Book review: Mee, L. (2022). Reanimated: The Contemporary American Horror Remake. Edinburgh University Press
“Horror Movies Always Know What We Did Last Summer”: Meta-Horror, Philosophy, and “The Cabin in the Woods”
The paper reviews Suzanne Kord's 2023 book dedicated to the film “The Cabin in the Woods.” It analyzes the film's meta-nature through allusions and references. The review explores philosophical themes addressed in the movie, including the clash between faith and nihilism, the ethical implications of self-sacrifice, humanity's place in the world, the individual versus humanity, and the issue of free will. It highlights the film's extradiegetic elements, emphasizing how “The Cabin in the Woods,” as a philosophical text, elicits a philosophical response from viewers. The paper presents Suzanne Kord's horror theory, which posits that the essence of the genre lies not in fear but in guilt. It offers an assessment and brief critique of this theory
Equation of state and opacities for hydrogen atmospheres of magnetars
The equation of state and radiative opacities of partially ionized, strongly
magnetized hydrogen plasmas, presented in a previous paper [ApJ 585, 955
(2003), astro-ph/0212062] for the magnetic field strengths 8.e11 G < B < 3.e13
G, are extended to the field strengths 3.e13 G < B < 1.e15 G, relevant for
magnetars. The first- and second-order thermodynamic functions and radiative
opacities are calculated and tabulated for 5.e5 < T < 4.e7 K in a wide range of
densities. We show that bound-free transitions give an important contribution
to the opacities in the considered range of B in the outer neutron-star
atmosphere layers. Unlike the case of weaker fields, bound-bound transitions
are unimportant.Comment: 7 pages, 6 figures, LaTeX using emulateapj.cls (included). Accepted
by Ap
Identification of the Factors of Sustainable Development of Regional Agricultural Systems Using Regression Model
The study is aimed at providing a theoretical basis for the relevance of sustainable development of regional agricultural systems and the development of practical recommendations for the implementation of the algorithm evaluation of the factors affecting the condition of agricultural production at the regional level. The study uses a systematic approach, supplemented with multifunctionality paradigm of agricultural production, which has enabled to develop an algorithm that includes a series of steps aimed at creating a regression model that reflects the significance of selected factors and their impact on the development of regional agricultural system. The developed method is tested in a study of rural areas of the Penza region, situated in the Central European part of Russia. The proposed indicators of sustainable development of regional agricultural systems are able to objectify the process of further evaluation of the spatial inhomogeneity of the factors determining sustainability of the agricultural production. The research findings provide additional opportunities in the agricultural development of the region.
Keywords: sustainable development factors, agricultural system, rural areas, regional development, regression model
JEL Classifications: 013, R1
Intact Cytoskeleton Is Required for Small G Protein Dependent Activation of the Epithelial Na+ Channel
BACKGROUND: The Epithelial Na(+) Channel (ENaC) plays a central role in control of epithelial surface hydration and vascular volume. Similar to other ion channels, ENaC activity is regulated, in part, by cortical cytoskeleton. Besides, the cytoskeleton is an established target for small G proteins signaling. Here we studied whether ENaC activity is modulated by changes in the state of the cytoskeleton and whether cytoskeletal elements are involved in small G protein mediated increase of ENaC activity. METHODS AND FINDINGS: First, the functional importance of the cytoskeleton was established with whole-cell patch clamp experiments recording ENaC reconstituted in CHO cells. Pretreatment with Cytochalasin D (CytD; 10 microg/ml; 1-2 h) or colchicine (500 microM; 1-3 h) to disassembly F-actin and destroy microtubules, respectively, significantly decreased amiloride sensitive current. However, acute application of CytD induced rapid increase in macroscopic current. Single channel measurements under cell-attached conditions revealed similar observations. CytD rapidly increased ENaC activity in freshly isolated rat collecting duct, polarized epithelial mouse mpkCCD(c14) cells and HEK293 cells transiently transfected with ENaC subunits. In contrast, colchicine did not have an acute effect on ENaC activity. Small G proteins RhoA, Rac1 and Rab11a markedly increase ENaC activity. 1-2 h treatment with colchicine or CytD abolished effects of these GTPases. Interestingly, when cells were coexpressed with ENaC and RhoA, short-term treatment with CytD decreased ENaC activity. CONCLUSIONS: We conclude that cytoskeleton is involved in regulation of ENaC and is necessary for small G protein mediated increase of ENaC activity
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