1 research outputs found
Neurotrophic keratitis in a patient with dihydroxypyrimidine dehydrogenase deficiency
We describe a case of neurotrophic keratitis in association
with dihydroxypyrimidine dehydrogenase (DHPD) deficiency.
Ocular manifestations in patients with DHPD are rare and
neurotrophic keratitis has never been reported before. A six-year-
old boy who was a known case of DHPD deficiency and born
of a consanguineous marriage presented to our clinic with non-
healing corneal ulcers in both eyes. Reduced corneal sensations
were detected and the patient was started on lubricating eye
drops. The patient continues to be on lubricant eye drops and
there has been no recurrence of the disease