Linking Quantitative Motor Assessments to the Underlying Brian Injury: A Preliminary Report

Using custom software and an inexpensive novel motion capture controller, we adapted and automated traditional subjective motor assessments in an integrated system to develop a quantitative motor assessment (QMA) that is low-cost, and highly sensitive. Twelve participants who have suffered a traumatic brain injury performed the QMA and had MRI scans of their brain. We compared the individual QMA results from the TBI group to normative standards (developed in an earlier work). We also compared the QMA results to measures of damage found in MRI results. Preliminary analysis of a subset of data are reported here

Reducing Sexual Risk among Racial/ethnic-minority Ninth Grade Students: Using Intervention Mapping to Modify an Evidenced-based Curriculum

Background: Racial/ethnic-minority 9th graders are at increased risk for teen pregnancy, HIV, and STIs compared to their White peers. Yet, few effective sexual health education programs exist for this population. Purpose: To apply IM Adapt—a systematic theory- and evidence-based approach to program adaptation—to modify an effective middle school sexual health education curriculum, It’s Your Game…Keep It Real! (IYG), for racial/ethnic-minority 9th graders. Methods: Following the six steps of IM Adapt, we conducted a needs assessment to describe the health problems and risk behaviors of the new population; reviewed existing evidence-based programs; assessed the fit of IYG for the new population regarding behavioral outcomes, determinants, change methods, delivery, and implementation; modified materials and activities; planned for implementation and evaluation. Results: Needs assessment findings indicated that IYG targeted relevant health and risk behaviors for racial/ethnic-minority 9th graders but required additional focus on contraceptive use, dating violence prevention, active consent, and access to healthcare services. Behavioral outcomes and matrices of change objectives for IYG were modified accordingly. Theoretical methods and practical applications were identified to address these behavioral outcomes, and new activities developed. Youth provided input on activity modifications. School personnel guided modifications to IYG’s scope and sequence, and delivery. The adapted program, Your Game, Your Life, comprised fifteen 30-minute lessons targeting determinants of sexual behavior and healthy dating relationships. Pilot-test data from 9th graders in two urban high schools indicate promising results. Conclusion: IM Adapt provides a systematic theory- and evidence-based approach for adapting existing evidence-based sexual health education curricula for a new population whilst retaining essential elements that made the original program effective. Youth and school personnel input ensured that the adapted program was age-appropriate, culturally sensitive, and responsive to the needs of the new population. IM Adapt contributes to the limited literature on systematic approaches to program adaptation

Low State, Phase-Resolved IR Spectroscopy of VV Puppis

We present phase-resolved low resolution $JHK$ and higher resolution $K$-band spectroscopy of the polar VV Pup. All observations were obtained when VV Pup was in a low accretion state having a K magnitude near 15. The low resolution observations reveal cyclotron emission in the $J$ band during some phases, consistent with an origin near the active 30.5 MG pole on the white dwarf. The secondary in VV Pup appears to be a normal M7V star and we find that the $H$ and $K$ band fluxes are entirely due to this star at all orbital phases during the low accretion state. We use our higher resolution Keck spectroscopy to produce the first $K$-band radial velocity curve for VV Pup. Our orbital solution yields $K_2$=414$\pm27$ km sec$^{-1}$ and leads to mass estimates of M$_1$=0.73$\pm$0.05 M$_{\odot}$ and M$_2$=0.10$\pm$0.02 M$_{\odot}$. We find that the mass accretion rates during the normal low states of the polars VV Pup, EF Eri, and EQ Cet are near 10$^{-13}$ M$_{\odot}$ yr$^{-1}$. The fact that \.M is not zero in low state polars indicates active secondary stars in these binary systems, including the sub-stellar donor star present in EF Eri.Comment: Accepted in Astronomical Journal 5 figure

Habitat Characteristics of Northern Bobwhite Quail-Hunting Party Encounters: A Landscape Perspective

Landcover data and bobwhite hunting records were used to assess both hunter habitat preferences and the frequency of northern bobwhite encounters by hunting parties in relation to habitat composition during the 1994-1995 and 1995-1996 hunting seasons at the Joseph W. Jones Ecological Research Center in southern Georgia. Patterns of habitat use by hunters, and the frequency of bobwhite encounters varied within and between years, depending on habitat quality, food availability, and other factors. Landscape-scale analyses of standardized bobwhite covey densities (based on coveys pointed in the field) and habitat composition and configuration for the 1994-1995 hunting season revealed that bobwhite densities were: (1) positively associated with the overall percentage agriculture and food plot habitat (reaching a maximum at 30-35% agriculture); and (2) positively associated with edge complexity, and positively associated with agricultural mean patch size [reaching a maximum at 2-3 hectares (5-6 acres)]. Consequently, larger food plots may be more important for increasing bobwhite encounter rates than numerous very small food plots [ \u3c 0.1 hectares (0.25 acres)]. Results of this, and related ongoing studies, have important implications for both landscape design and multiple use resource management. activities in the context of northern bobwhite habitat management in southern upland pine forest ecosystems

Lived Experiences of American Adults who Survive COVID-19: Implications for Physical Activity and Interpersonal Stress

Introduction: The cumulative number of COVID-19 cases has surpassed 579 million globally. Symptoms during and after COVID-19 infection vary from mild cold symptoms to severe multisystem illness. Given the wide range of symptom presentations and complications post COVID-19, the purpose of this study was to describe the lived experience of American adults surviving COVID-19. Method: This study employed an exploratory qualitative description design. Semi-structured interviews were conducted with a sample of 35 individuals, [white (94%), female (71%), mean age = 43.7 years], with proximity to a university in an urban Midwest American city. Interviews occurred between May and August 2021, three or more months after participants tested positive for COVID-19. Results: Forty percent of the 35 participants experienced prolonged COVID-19 symptoms impacting their lifestyle. Four themes characterized the impacts of the post COVID-19 condition on the lives of the participants within the context of a global pandemic: (a) disruptions in health & well-being, (b) persistent uncertainty, (c) disruptions in interpersonal relationships, (d) beneficent outcomes and adaptation. Discussion: This study of COVID-19 has identified important implications for physical activity and interpersonal stress. Prolonged COVID-19 symptoms led to disruptions in the health, well-being, and interpersonal relationships of participants. Healthcare professionals need to attend to symptoms post COVID-19, assess interpersonal functioning, and provide guidance on physical activity. Future studies are recommended to track consequences of COVID-19’s impact on long-term health and well-being

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AACP Special Taskforce White Paper on Diversifying Our Investment in Human Capital

The 2015-2017 American Association of Colleges of Pharmacy (AACP) Special Taskforce on Diversifying our Investment in Human Capital was appointed for a two-year term, due to the rigors and complexities of its charges. This report serves as a white paper for academic pharmacy on diversifying our investment in human capital. The Taskforce developed and recommended a representation statement that was adapted and adopted by the AACP House of Delegates at the 2016 AACP Annual Meeting. In addition, the Taskforce developed a diversity statement for the Association that was adopted by the AACP Board of Directors in 2017. The Taskforce also provides recommendations to AACP and to academic pharmacy in this white paper

Phase-Resolved Infrared H- and K-band Spectroscopy of EF Eridani

We present new phase-resolved H and K-band spectroscopy of the ultra-short period magnetic cataclysmic variable EF Eri in its current, prolonged ``low'' state obtained using NIRI on Gemini-North, and NIRSPEC on Keck II. These new data show that the H-band spectrum of EF Eri appears to be dominated by cyclotron emission during the entire orbital cycle. The {\it K}-band spectrum of EF Eri is likewise dominated by cyclotron emission during most of an orbital period, but near binary phase 0.0, the secondary star spectrum may be visible. We conclude that strong, and highly variable cyclotron emission is responsible for the photometric variation previously reported for EF Eri. The nature of this cyclotron emission is complex: the H-band spectra show that the dominant cyclotron harmonic at phase 0.5 peaks at 1.65 $\mu$m, but at phase 0.0, the harmonic peaks near 1.72 $\mu$m. At phase 0.5, there is another cyclotron feature present that peaks in between the H and K bands (near 1.93 $\mu$m), but at phase 0.0, no such feature is present. These data suggest that cyclotron emission from both poles is occurring.Comment: 23 pages of text, 8 figure

Regulatory mechanisms controlling biogenesis of ubiquitin and the proteasome

Analysis of several Saccharomyces cerevisiae ump mutants with defects in ubiquitin (Ub)-mediated proteolysis yielded insights into the regulation of the polyubiquitin gene UB14 and of proteasome genes. High-molecular weight Ub-protein conjugates accumulated in ump mutants with impaired proteasome function with a concomitant decrease in the amount of free Ub. In these mutants, transcriptional induction of UB14 was depending in part on the transcription factor Rpn4. Deletion of UB14 partially suppressed the growth defects of ump1 mutants, indicating that accumulation of polyubiquitylated proteins is deleterious to cell growth. Transcription of proteasome subunit genes was induced in ump mutants affecting the proteasome, as well as under conditions that mediate DNA damage or the formation of abnormal proteins. This induction required the transcriptional activator Rpn4. Elevated Rpn4 levels in proteasome-deficient mutants or as a response to abnormal proteins were due to increased metabolic stability. Up-regulation of proteasome genes in response to DNA damage, in contrast, is shown to operate via induction of RPN4 transcription. (C) 2004 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.info:eu-repo/semantics/publishedVersio